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Succinylcholine으로 유발된 Fasciculation과 Myalgia에 대한 Diazepam과 d-tubocurarine 전처치의 비교효과
최세진,길기진,이정은 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.2
Succinylcholine-induced muscle pain well documented. It is common to use subparalyzing dose of a non-depolarizing muscle relaxant before succinylcholine and accepted in clinical practice forpreventing of succinylcholine-induced fasciculation and it's associated sequalae. But it is needed to give large dose of succinylchcline to offer adeguate relaxation for tracheal intubation in these pretreated cases. This present study was undertaken to compare the effect of diazepam with d-tubocurarine on succinylcholine induced side effects. Sixty cases were studied if four different groups. In 1st group : no pretreatment, 2nd group : diazepam(0.05mg./kg.), 3rd group : diazepam(0.1 mg./kg.), 4th group : d-Tc.(0.05mg./kg.). The following results were obtained : 1. Diazepam pretreatment groups had no significant changes for the prevention of muscle fasciculation following succinylcholine compare to control group, but prevention of muscle fasciculation by d-Tc. pretreatment were significant. 2. Conditions for intubation were excellent in all groups. 3. In the prevention of muscle pain, there was no significant difference between the control and diazepam pretreatment group but significant difference between the control and d-Tc. prtreatment. 4) There was no specific relationship between muscle fasciculation and muscle pain.
CSA 팽창재를 혼입한 강섬유 보강 콘크리트의 역학적 성능 및 균열 저항성능 평가
최세진,박기태,권성준 한국구조물진단유지관리공학회 2014 한국구조물진단유지관리공학회 논문집 Vol.18 No.1
콘크리트의 취성파괴를 방지하기 위해 강섬유 보강재는 효과적인 복합재료이다. 그러나 시멘트 사용량이 많아지면 건조수축이 증가하고이로 인해, 강섬유 보강재의 연성증가 효과가 제한될 수 있다. 팽창재를 사용한 콘크리트 내부의 강섬유 보강재는 화학적 프리스트레싱 효과가 발생하여 강섬유 보강효과를 증가시킬 수 있다. 본 연구에서는 CSA 팽창재와 강섬유 보강재를 혼입하여 콘크리트의 역학적인 특성을분석하였다. 체적비 1~2%의 강섬유 보강재와 시멘트 중량의 10%의 CSA 팽창재를 혼입하였으며, 다양한 역학적 특성과 휨거동을 분석하였다. 강섬유 보강재를 혼입한 CSA 콘크리트는 인장강도와 초기균열강도의 증가를 나타냈으며, 균열후의 파괴에너지 증가와 같은 연성거동을 뚜렷하게 나타내었다. 적절한 팽창재 사용과 최적의 강섬유 보강재의 혼입률이 도출된다면 이들의 상호작용은 콘크리트의 취성을 더욱 효과적으로 제어할 수 있다. In order to prevent brittle failure of concrete, steel fiber reinforcement is effective composite material. However ductility of steel fiber reinforced concrete may be limited due to shrinkage caused by large content of cement binder. Chemical prestressing for steelfiber reinforcement in cement matrix can be induced through expansive admixture and this can increase reinforcing effect of steel fiber. In this study, mechanical performances in concrete with CSA (Calcium sulfoaluminate) expansive admixture and steel fiberreinforcement are evaluated. For this work, steel fiber reinforcement of 1 and 2% of volume ratio and CSA expansive admixture of 10% weight ratio of cement are added in concrete. Mechanical and fracture properties are evaluated in concrete with steel fiber reinforcement and CSA expansive admixture. CSA concrete with steel fiber reinforcement shows increase in tensile strength, initialcracking load, and ductility performance like enlarged fracture energy after cracking. With appropriate using expansive admixture and optimum ratio of steel fiber reinforcement, their interactive action can effectively improve brittle behavior in concrete.
탈극성근이완제 사용후 나타난 근육통과 전해질변동의 예방에 관한 연구
최세진,박성택,김영진 충남대학교 의과대학 지역사회의학연구소 1981 충남의대잡지 Vol.8 No.2
Postoperative muscle pain and transient increase in serum potassium concentration are well known to occur in man following intravenous administration of succinylcholine. A number of methods for prevention of muscle pain and serum electrolyte changes have been suggested but none of the technics has proved entirely effective. To investigate methods for the prevention of muscle pain and electrolyte changes after intravenous injection of succinylcholine, we studied four groups, a succinylcholine group and three pretreatment groups(d-Tc+succinylcholine, mioblock+succinylcholine, gallamine+succinylcholine). The results were as follows: 1) The incidence of muscle pain was 100% in the succinylcholine group and 63% in the pretreatment groups. Especially in the mioblock pretreatment group was noticed good result. 2) The muscle pain usually appeared within 24 hours after operation and disappeared within two days in pretreatment groups. 3) The degree of muscle fasciculation showed a significant decrease (from 80% to 30%) with pretreatment groups. 4) The degree of muscle relaxation during intubation in four groups were not significantly different. 5) In succinylcholine administration group, potassium concentration was slightly increased at 15 minute but significantly decreased at 45 minute. 6) In mioblock or d-Tc pretreatment group, sodium conentration was significantly decreased at 30 minute. 7) In gallamine pretreatment group, chloride concentration was significantly decreased at 45 minute.