출산위험성이 높은 연령군의 피임수용에 관한 특성

최경숙 중앙대학교 의과대학 의과학연구소 1981 中央醫大誌 Vol.6 No.1

1974년 9월부터 12월에 걸쳐 경제기획원 조사통제국과 가족계획 연구원이 세계 출산력 조사의 일환으로 실시한 한국 출산력 조사의 가족계획실태 조사결과를 이용하여 임신과 출산의 위험성이 높은 연령군인 25세부터 34세까지의 기혼부인중 가임유배부인 2,167명을 통하여 알아본 피임수용에 관한 특성은 다음과 같다. 1) 자녀의 규모는 평균 2-3명 이하의 자녀를 희망하고 있다. 젊은층의 부인들에게 있어서는 가족계획사업에 영향을 받아 차츰 억은수의 자녀를 갖기 원하고 또한 가족형태가 과거의 대가족제도에서 소가족제도로 바뀌면서 한층 더 적은수의 자녀를 원하고 있다. 교육수준이 높은 부인에게서 거주지가 도시인 부인에게서 적은수의 자녀를 원하는 경향이 더 크고 이러한 양상은 앞으로의 인구성장율에 큰 영향을 줄 것이다. 2) 피이방법에 대한 지식은 효과적인 피임방법에 들어본 적이 있는 경우가 대상부인의 99.3%에 속하며 잘 알려진 피임 방법으로는 먹는 피임약(98.1%), 자궁내장치(95%), 장관수술(89%), 콘돔(83%), 여성불임술(73%) 등의 순서이다. 3) 피임방법 사용경험은 대상부인중 56%가 최소한 한가지 이상의 효과적인 피임방법을 사용한 경험이 있으며 피임방법별로는 먹는 피임약(38%)이 가장 많이 사용되었고 다음이 콘돔(26%), 루우프(23%), 월경주기법(20%)의 순서이었다. 4) 가임유배우 부인중 현재 임신중인 부인을 제외한 임신노출상태에 있는 부인의 피임을 목적으로한 붙임 수술을 포함한 현피임실천율은 43.5%이다. 이들을 사용되고 있는 피임방법별로 보면 43.5%의 실시자중 먹는 피임약과 자궁내장치(20.4%)가 약 반을 차지하고 그 다음은 콘돔과 월경주기법이 사용되고 있다. 5) 현재 피임 실천율은 부인의 교육수준이 높을수록 남편의 직업이 관리직이나 전문적인 경우에 높게 나타나고 거주지별로는 현존자년수가 적은 경우에 도시지역에서 피임실천율이 높다. 6) 자녀를 더이상 원치않는 부인중 임신노출상태에 있음에도 불구하고 현재 효과적인 피임방법을 실시하지 않는 부인은 57%이었다. 위의 여러결과로 보아 가족계획사업이 효과적으로 이루어지기 위해서는 특별히 가족계획을 필요로 하는 집단을 대상으로 집중적을고 실시되어야겠다. 이들 집단은 임신노출상태에 있으면서 자녀를 더 이상 원치않는 부인이 대상이 되며 이들이 효과적인 피임방법을 사용할 수 있도록 사업계획을 세워야겠으며 이를 위해서는 먼저 자녀를 더이상 원치 않으면서 임신 노출상태에 있음에도 불구하고 효과적인 피임방법을 사용하지 않는 이유를 찾아야겠다. An important aim of this study is to analy the characteristics of acceptance of contraceptives, in fecund Korean women. The data used in this study were obtained from 'the 'Survey' of the korean Institute of Family Planning during the period of September to December in 1974, Of 2, 167 currently married "Fecund" women, the results were as follows: 1. Most of the Currently married "Fecund" women, wish to have two or three children. 2. Most of the "Fecund" women (99.3%) have experience of hearing one of the efficient. contraceptive methods: The speafied contraceptive methods were oral pill 98.1%. intrauterine device (IUD) 95.4%, sterilization of husband 89.3%, condom 83.1% and sterilization of wife 73%, in order. 3. One thousand two hundred and eighteen (56.2%) women have ever been used one of the efficient method: the specified methods were oral pill 38%, condom 26%, IUD 23% and rhythm method 20%, in order. 4. Of 1,843 "Exposed" women, 802 (43.5%) women are using either contraceptive method or sterilization: the specified method were oral pill 10.6%, IUD 9.8%, condom 8.1%, rhythm method 6.2%, respectively. 5. Of 1,271 "Exposed" women who wanted no more children, 723 (56.9%) women are using neither one of the efficient methods nor sterilization.

가족성 정신분열병 환자에서 임상 특성의 가족내 연관성

최경숙,이유상,장용이,조은영,전현옥,김창현,김상욱,홍경수 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5

Objectives : This study aims at examining familial associations of symptoms and clinical characteristics in affected sibling or relative pairs of schizophrenia as an effort to identify genetically homogeneous phenotypes. Methods : Forty-seven relative pairs with DSM-IV diagnosis of schizophrenia from thirty-five Korean families multiply affected with schizophrenia were ascertained. Direct interviews were done using the Korean version of Diagnostic Interview for Genetic Studies (DIGS). The Krawieka Rating Scale and the Schedule for the Deficit Syndrome were also applied for further evaluation of psychopathologies. Intra-familial concordances and correlations of clinical characteristics and symptoms were tested using χ² -test and Spearman's correlation. Results : Significantly high concordance rate within relative pairs was found for the diagnosis of paranoid vs. non-paranoidsubtype (χ²=7.623, P=0.006, df=1). Deficit vs. non-deficit syndrome also showed significant concordance (χ² =3.850, p=0.0497, df=1). Among single symptom items in DIGS, only 'auditory hallucination' showed significant concordance rate ( χ² =5.503, P=0.019, df=1). Factor analysis for symptoms items in the Rrawiecka Rating Scale indicated three symptom dimensions ; negative, psychotic and affective, Psychotic (P =0.442, P=0.003) and affective dimension scores (p =0.427, P=0.004) showed significant intra-familial correlations. Age at onset of recognized psychotic symptoms showed significant correlation only within the male sibling pairs. Conclusion : Familial factors, Possibly genetic factor contribute to the phenotypic characteristics of paranoid vs. non-para-noid subtype, deficit vs. non-deficit syndrome, auditory hallucination, and affective syndrome, It supports their use in the delineation of homogeneous subgroups for future genetic studies.

일부 산업재해 환자들에서 외상후 스트레스장애

최경숙,임채기,최재욱,강성규,염용태 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.3

연구목적 : 우리나라에서 산업 재해로 신체적 손상을 입고 입원해 있는 일부 근로자들을 대상으로 PTSD 발병여부를 조사하고, 산업 재해와 관련된 위험 인자를 파악하여 산업재해 이후 근로자들이 겪게 될 신체적 건강문제 뿐만 아니라 정신적 건장 문제 회복에 도움을 주고자 하였다. 방 법 : 2000년 7월에서 2000년 9월 사이에 산업 재해로 인해 신체적인 부상을 입고 입원 중인 인천 소재 산재병원의 남성 입원환자 47명을 대상으로 PTSD 발병여부와 관련 인자를 연구하기 위하여 구조화된 설문 조사와 CAPS를 이용한 진단적 면담을 시행하였다. 결 과 : CAPS를 이용한 면접조사 결과 최종 연구 대상자 47명중 12명(25.5%)이 PTSD로 나타났으며, 모두 증상의 지속 기간이 3개월 이상인 만성 외상후 스트레스장애로 분류되었다. PTSD군 12명과 non-PTSD군 45명을 비교한 결과 BDI, STAI-I, STAI-II, IES 점수는 PTSD 군에서 유의하게 높게 나타났다. 또한 SCR-90-R의 세부항목 중 편집 사고를 나타내는 PAR 점수가 유일하게 두 군 사이에 유의한 차이를 보이지 않았고 그 외의 항목들은 PTSD 군에서 유의하게 높았다. 산재 관련 위험 인자의 비교에서 환자가 주관적으로 보고한 의식의 상실 경험만이 PTSD군에서 유의하게 높게 나타나 이전의 다른 연구자와 일치된 소견을 보였다. 결 론 : 이상의 결과는 산재 사고 이후에 PTSD가 발생하고, 증상이 장기간 지속되어 만성화를 겪을 가능성이 있다는 것을 보여준다. 위험 인자 중에서 사고 관련 위험 인자로 의식의 상실에 대한 주관적인 보고만이 관련성이 있는 것으로 나타났으나, 그 외의 다른 인자들은 관련서이 없는 것으로 나타났다. 그러나 여러 가지 연구의 제한점이 많으므로 연구 시점을 달리하고 많은 대상자를 포함한 후속 연구를 시행해야 산업재해와 PTSD에 대한 이해를 높일 수 있을 것으로 사료된다. Objectives : This study was conducted to assess the development of posttraumatic stress disorder(PTSD) after occupational physical injuries and the risk factors in occupational accident patients for PTSD. Methods : Forty-seven occupational accident patients with physical injuries were administered BDI. STAI I and II, SCL-90-R, IES and questionnaires for risk factors and Clinician-Administered PTSD Scale(CAPS). Results : 1) 12 patients(25%) were diagnosed as PTSD. 2) The BDI, STAI I and II and IES scores are significantly high(<0.05) in PTSD group than non-PTSD group. 3) The subscales of SCL-90-R, with an exception of PAR subscale, showed higher scores(<0.05) in PTSD group. 4) The loss of consciousness(LOC) was only significant risk factor in the occupational accident related factors(<0.05). Conclusion : The results of this study show the development of PTSD among occupational accident patients. The loss of consciousness(LOC) was the only significant risk factor for PTSD in occupational accident patients.

사업장내 정서적 위기

최경숙,Choe, Gyeong-Suk 대한산업보건협회 2006 산업보건 Vol.219 No.-

어린이집 건축계획기준을 위한 기초 연구

최경숙,배시화,강미선,주서령 대한건축학회 2000 대한건축학회논문집 Vol.16 No.12

직관과 장독립 인지양식과의 관계

최경숙 성균관대학교 인문과학연구소 1988 人文科學 Vol.18 No.1

만성환자 가족의 병인성 스트레스와 대처에 관한 연구

최경숙,류은정,우혜주 중앙대학교 의과대학 의과학연구소 1994 中央醫大誌 Vol.19 No.3

The purpose of this study is to describe the family coping with chronic illness by the family member's definition of the event, the pile-up of family stressors and strains, and the severity of illness. One hundred seventy nine family members of chronic illness patient responded a questionnaire. Family coping was measured with the family crisis oriented personal evaluation scales, a twenty eight item 5-point Likert scale. The pile-up of family stressors was measured with the family inventory of life events, a twenty five item inventory stressors. Family perception of the illness was measured with the family member definition of chronic illness scale, a fourteen item measure developed for the study. Severity of chronic illness was determined using stage of chronic illness process and cure. The patient's family role was elicited on the demographic questionnaire. Multiple regression analysis, t-test, two-way ANOVA, ANOVA and Canonical correlation were used to answer the research questions. When each variable was reiationship, the definition of the event and family inventory of life event wer predictor for family coping (R=0.72, Willk's Lambda p=0.0001 and f=1.30, p=0.013). When the family member's perception of the chronic illness was used a bivariate relationship, it became a significant family coping as well(F=3.52, p=0.0001). The degree of the family coping by family perception of chronic illness was relatively high.

우리나라 산재보험의 정신질환 인정실태

최경숙,이현주,김세진,이창화 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.3

Objectives : The purpose of this study was to determine characteristics of work-related psychiatric injuries with Korean Workers' compensation data. Methods : We analyzed the distribution of sex, age, types of work-related psychiatric disorders, type of industry and occupation. Using the data of 3175 Korean workers' compensation cases who were compensated for work-related psychiatric injuries from 2001 to 2003. Results : Work-related psychiatric injuries have increased annually. 897 cases, 1099 cases and 1179 cases were compensated during three years (2001-2003). Men accounted for many more cases than women. The most common age group was 41 -49. The majority of work-related psychiatric injuries were 'organic, including symptomatic, mental disorders', 'neurotic, stress-related and somatoform disorders' and 'mood [affective] disorders'. For accidental psychiatric injury cases construction and manufacturing were the most common industries. Manufacturing, business activities, construction and transport were common in regard to work-related psychiatric disorders. In this study there was a high frequency of craft and related trades workers, elementary occupations and plant and machine operators and assemblers in accidental psychiatric injury cases. Work-related psychiatric disorders were frequent for elementary occupations, plant and machine operators and assemblers, craft and related trades workers, service workers, legislators, senior officials and managers. Conclusion : This investigation provided more information about the psychiatric injuries of Korean workers. These findings should help formulate intervention and prevention strategies of work-related psychiatric disorders.

현장실험을 통한 침사구의 효과 분석

최경숙,장정렬,Choi, Kyungsook,Jang, Jeongryeol 한국관개배수위원회 2014 한국관개배수논문집 Vol.21 No.1

This study investigated the effects of NPS(non point source) pollution reduction of sediment traps through field experiments. Various sizes of 4 sediment traps were applied in a upland field located in Gunwi and assessed the infiltration and storage effects as well as NPS pollution reduction effects of this technique. The characteristics of deposited soil in the sediment traps were also analyzed including distribution of particle size, soil texture, and chemical properties. The results showed that slightly different composition of soil particle size from each sediment trap with high proportion of 0.15mm and 0.25mm ranges of soil particle diameters, while the loamy sand is the main types of deposited soils in the sediment traps. Decreased NPS pollution were observed from the water quality analysis of the samples taken from the sediment traps. Further research need to be proceeded continuously to improve this technique in order to utilize on upland fields for management of agricultural NPS pollutions.

Autophagy and cancer

최경숙 생화학분자생물학회 2012 Experimental and molecular medicine Vol.44 No.2

Basal autophagy plays a critical role in maintaining cellular homeostasis and genomic integrity by degrading aged or malfunctioning organelles and damaged or misfolded proteins. However, autophagy also plays a complicated role in tumorigenesis and treatment responsiveness. It can be tumor-suppressing during the early stages of tumorigenesis (i.e., it is an anti-tumor mechanism), as reduced autophagy is found in tumor cells and may be associated with malignant transformation. In this case, induction of autophagy would seem to be beneficial for cancer prevention. In established tumors, however, autophagy can be tumor-promoting (i.e., it is a pro-tumor mechanism), and cancer cells can use enhanced autophagy to survive under metabolic and therapeutic stress. The pharmacological and/or genetic inhibition of autophagy was recently shown to sensitize cancer cells to the lethal effects of various cancer therapies, including chemotherapy,radiotherapy and targeted therapies, suggesting that suppression of the autophagic pathway may represent a valuable sensitizing strategy for cancer treatments. In contrast, excessive stimulation of autophagy may also provide a therapeutic strategy for treating resistant cancer cells having high apoptotic thresholds. In order for us to develop successful autophagy-modulating strategies against cancer, we need to better understand how the roles of autophagy differ depending on the tumor stage, cell type and/or genetic factors, and we need to determine how specific pathways of autophagy are activated or inhibited by the various anti-cancer therapies.