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장미애,오소희,노혜미,천선영,오혜영,박경희,백유진,송홍지 대한가정의학회 2015 Korean Journal of Family Medicine Vol.36 No.6
Background: This study examined the differences in factors associated with albuminuria according to gender and comorbidities of hypertension (HTN) and diabetes mellitus (DM). Methods: We included 3,859 participants aged 20 to 79 years (55% female) from the 5th Korea National Health and Nutrition Examination Survey. Participants were excluded if they took antihypertensive or anti-diabetic medication, had chronic renal failure, had malignant tumor, were pregnant or menstruating during the health examination, or had missing urine albumin data. Albuminuria was defined by the participant’s urine albumin-creatinine ratio (uACR). Relationships between dependent and independent variables were analyzed using the Pearson’s correlation test and simple linear regression. Due to possible muticollinearity, multiple linear regression analysis was used to determine whether the association between the dependent and independent variables of interest remained significant after adjustment for other potentially confounding independent variables. Results: The variables significantly correlated with uACR were different between the genders and between subjects with HTN or DM as a comorbidity. In the multiple linear regression models, hemoglobin A1c (P=0.01) was positively associated with uACR in men without HTN and DM. In men with HTN or DM, systolic blood pressure and fasting glucose (P<0.01) were positively associated with uACR. In women with HTN or DM, waist circumference (P=0.011) and gamma-glutamyl transpeptidase (P<0.001) were positively correlated with uACR (P<0.05) and glucose level (P=0.019) was negatively correlated with uACR. Conclusion: The study suggested factors correlated with albuminuria were different for men and women according to comorbidities such as HTN and DM.
대학생의 편의점 식품 및 HMR 이용실태와 품질개선 요구도 조사
안진수,김승대,천소희,이나영 대전대학교 기초과학연구소 2017 自然科學 Vol.28 No.-
The purpose of this study was to investigate college students’ the use of foods and HMR products and the needs for quality improvement of HMR products at convenience stores. A total of 199 respondents in Daejeon were surveyed. As a results, 30.7% of respondents were freshmen, and 29.6% were sophomores. The number of college students who spent more than 400,000 won for one month's allowance was the most (24.1%). Food expenses, including eating out, were the highest among respondents who use 200,000 won or more and less than 300,000won (34.7%). The number of visits to convenience stores was 34.7%, who visited three to four times a week. The most important factor for convenience store selection was ‘distance from home (45.7%)’ and the most important criterion for food selection was ‘taste (52.8%)’. The most frequently purchased food items at convenience stores were carbonated drinks, followed by snacks, coffee, triangular gimbap, and cup noodles. There were significant differences in the purchase frequency of foods according to the gender of respondents, such as hamburgers(p<0.001), snacks (p<0.05), coffee (p<0.001), bottled water (p<0.001), alcohol (p<0.001), and tobacco (p<0.001). The reasons for using HMP products of the convenience store were 'I want to eat lightly (21.9%)' at the highest rate, and the selection criterion of HMR products was 'taste (57.8%)' as the most important. For the 'taste' quality, the woman's demand score of quality improvement for HMR was significantly higher than the man's demand score (p<0.01).
세포유전검사와 형광동소보합법에 의한 Yq 결실의 산전 진단
박인양 ( In Yang Park ),천소희 ( So Hee Cheon ),김명신 ( Myung Shin Kim ),손정옥 ( Jung Ok Son ),이영 ( Young Lee ),신종철 ( Jong Chul Shin ),김창이 ( Chang Yi Kim ) 대한주산의학회 2004 Perinatology Vol.15 No.4
목적 : 산전 염색체 검사상 표지염색체가 관찰되는 경우 정확한 진단을 위한 지침이 설정되어 있지 않다. 본 연구를 통해 표지염색체의 기원을 알기 위한 순차적인 진단적 접근 방법을 제안하고자 한다. 방법 : 월경주기와 임신 첫 삼분기 초음파 검사상 제태연령 19주인 태아로 모체혈청삼중표지자 검사 소견상 다운 증후군 고위험군 소견을 보여 양수 염색체 검사를 시행하였다. NOR banding을 시행하고, chromosome X α satellite probe (DXZI) & chromosome Y α satellite probe (DYZ3) (Cy-tocell, Bambury, UK)와 CEP X/Y (Xp11.1-q11.1 CEP X α satellite & Yq12 CEP Y satellite III)(Vysis, IL, USA) 두 종류의 성염색체 표지자를 이용하여 형광동소보합법을 시행하였다. 결과 : 염색체 검사 결과 46,X,+mar 소견을 보였다. NOR banding에서 표지염색체는 염색되지 않아 그 기원이 끝곁매듭염색체일 가능성이 적은 것으로 생각되었다. 형광동소보합법 결과 표지염색체에 Y 중심절 signal이 관찰되었고 Yq12 signal은 관찰되지 않아 Yq11.2 부분부터 결실이 있음을 알 수 있었다. 결론 : 색체 검사 시 표지염색체가 관찰되는 경우 NOR banding과 FISH를 이용한 순차적 검사가 보다 효과적 진단 방법으로 생각된다. Objective : The accurate evaluation of a marker chromosome has been limited during prenatal karyo-typing. We proposed a method of step-by-step approach to evaluate the origin of a marker chromosome. Methods : A patient with 19 weeks of gestation was transferred to our hospital for karyotyping due to abnormal Triple test. Karyotyping of amniotic fluid was performed. NOR (nucleolar organizer region) banding and FISH (fluorescence in situ hybridization) using two types of sex chromosome probes: chromosome X α satellite probe (DXZI) & chromosome Y α satellite probe (DYZ3)(Cytocell, Bambury, UK) and CEP X/Y (Xp11.1-q11.1 CEP X α satellite & Yq12 CEP Y satellite III)(Vysis, IL, USA) were done. Results : The routine chromosomal analysis showed 46,X,+mar. As the result of NOR banding, we supposed that the marker chromosome was less likely originated from acrocentric chromosomes. FISH analysis revealed Y centromere signal on marker chromosome, but Yq12 signal was not detected. Therefore the marker chromosome was identified as Y chromosome formed by deletion at Yq11.2. Conclusion : This study demonstrated that FISH and NOR banding technique is more effective method for a marker chromosome evaluation during prenatal karyotyping.
최운민,홍승표,김지훈,천소희,민기옥,문희봉,김창이,고영미 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.5
제왕 절개술 후 발생한 괴사성 근막염은 항생제의 발달로 드문 합병증으로 인식되고 있으며 높은 치사율을 보이는 드문 질환으로 진단즉시 적절한 항생제와 수액 제제 투여와 괴사된 근막 조직의 광범위한 절제와 클린싱만이 폐혈증성 쇼크와 심폐기능의 손상을 막을 수 있으며 저자들은 30세 초산부에서 제왕절개술 후 발생한 괴사성 근막염 1예를 경험 치료하였기에 문헌 고찰과 함께 보고하는 바이다.