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진호준,김효상,윤형진,나기영,김연수,채동완,김성권,송영림,박민선 대한의학회 2009 Journal of Korean medical science Vol.24 No.-
Reactive oxygen species have been known to be an important factor in the pathogenesis of hypertension. Bilirubin, one of the metabolites of heme degraded by heme oxygenase, is a potent anti-oxidant. We verified the effect of serum bilirubin level on the incidence of hypertension in normotensive subjects. We grouped 1,208 normotensive subjects by the criterion of the highest quintile value of serum bilirubin, 1.1 ㎎/dL. The incidence of hypertension was higher in group 1 with bilirubin less than 1.1 ㎎/ dL than in group 2 with bilirubin 1.1 ㎎/dL or more (186/908 vs. 43/300, p=0.018). The relative risk for hypertension was 0.71 (95% confidence interval, 0.51-0.99), p=0.048 in group 2 compared to group 1 by Cox’s proportional hazard model. Among the groups stratified by gender, smoking, and liver function status, the group 2 showed a lower risk of hypertension in females and in non-smokers. In conclusion, a mild increase within the physiological range of serum bilirubin concentration was negatively correlated with the incidence of hypertension. The effect of bilirubin on the development of hypertension was more evident in females and in non-smokers.
IoT 사이버공격 사례분석을 통한 공격 유형 및 대응방안 연구
진호준,노창현,서정택 한국차세대컴퓨팅학회 2022 한국차세대컴퓨팅학회 학술대회 Vol.2022 No.05
IoT는 개별적인 목적에서 적용하기 위해 사용되었으나, 최근에는 의학, 농업뿐만 아니라 다방면에서 사용되고 있다. 2016년 Mirai 봇넷의 발현으로 인해 DNS 서버가 멈추는 사례가 있었다. 이러한 공격을 막기 위해 Mirai 봇넷과 같은 악성코드의 분석이 필요하다. 본 연구는 IoT 대상 악성코드 사례를 바탕으로 공격 대상과 특징 그리고 변종 악성코드들을 분석하고, 악성코드들이 나타날 수 있는 행위를 분석한다. 이를 통해 악성코드와 취약점을 매핑해 앞으로 나타날 수 있는 악성코드들의 특징에 대응하는 정형화 기법을 연구하고자 한다.
진호준,나기영,Soo Jin Kim,Kook-Hwan Oh,김연수,임춘수,김성권,채동완 대한의학회 2005 Journal of Korean medical science Vol.20 No.6
The roles of interleukin-10 (IL-10) have been emphasized in several models of glo-merulonephritis (GN). Three biallelic polymorphisms within the IL-10 promoter region, at positions -1,082, -819, and -592 from the transcription initiation site, were shown to affect the level of IL-10 production. To investigate the effect of IL-10 promoter polymorphisms on the predisposition to development of GN in Korea, IL-10 promoter polymorphisms were assayed by polymerase chain reaction followed by restriction fragment length polymorphism in 108 patients with IgA nephropathy (IgAN), 49 focal segmental glomerulosclerosis (FSGS), and 100 healthy controls. In comparison with the control, the frequency of -1,082*G alleles were lower in IgAN and the frequen-cies of -592*C and -819*C were lower in FSGS, respectively. As for the haplotype, GCC haplotype was less frequent among IgAN than the control and ATA haplotype was more frequent among FSGS than the control (p<0.05). The frequency of inter-mediate producer genotypes (GCC/ACC and GCC/ATA) were lower among IgAN or FSGS than the control. Our findings suggested that IL-10 promoter polymorphism predisposed to the development of IgAN and FSGS in Korean patients.
SNOMED CT 기반으로 한 주 증상 표준화와 표준화 세트의 전자의무기록 적용
진호준,김성권 대한의료정보학회 2003 Healthcare Informatics Research Vol.9 No.3
영어제목: Chief Complaint based on SNOMED저 자: 진 호 준 Ho Jun Chin,MD , 김 성 권 Suhnggwon Kim, MD, PhD