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      • KCI등재

        증례 : 감염 ; Hypervirulent Klebsiella pneumoniae에 의한 괴사근막염과 요근 농양

        진수신 ( Su Sin Jin ),김윤정 ( Youn Jeong Kim ),김상일 ( Sang Il Kim ),허주연 ( Joo Yeun Hu ),김유승 ( Yu Seung Kim ),조성연 ( Sung Yeon Cho ),강문원 ( Moon Won Kang ) 대한내과학회 2013 대한내과학회지 Vol.85 No.5

        Hypervirulent K. pneumoniae (hvKP)는 아시아에서 침습성 감염을 일으키는 주요 원인균으로 주로 원발성 간농양과 전이성 감염을 일으킨다. 괴사근막염은 드물게 발생하는 hvKP의 감염증상으로, 빠르고 심한 질환의 경과를 보이므로 적절한 항생제와 빠른 수술적 치료가 환자의 예후에 중요하다. 저자들은 당뇨 환자에서 상처를 통해서 침입한 hypermucoviscous phenotype을 가진 hvKP에 의해 발생한 괴사근막염과 요근 농양을 국내에서 처음으로 경험하였기에 문헌고찰과 함께 보고하는 바이다. A 62-year-old diabetic female was admitted to the hospital with fever and pain in both legs. Computed tomography scans of the abdomen revealed necrotizing fasciitis of the right thigh extending into the abdominal wall, and abscesses on the right psoas muscle. Magnetic resonance imaging showed increased T2 signal intensity along the peroneus muscle and fascia of the lower left leg. The patient received antibiotics and underwent debridement of the infected and necrotic tissue. Intra-abdominal abscesses were drained. Blood and pus cultures showed growth of Klebsiella pneumoniae, as had been suspected due to string test results showing hypermucoviscosity. Free-skin grafts were performed to repair tissue loss and the patient was subsequently discharged 82 days after admission. This represents the first reported case of necrotizing fasciitis and psoas muscle abscess caused by a hypervirulent strain of K. pneumoniae in Korea. (Korean J Med 2013;85:540-544)

      • KCI등재후보

        면역 능력이 있는 성인에서의 장폐색을 동반한 단일 공장 결핵 1예

        배현진 ( Hyun Jin Bae ),박종호 ( Jong Ho Park ),진수신 ( Su Sin Jin ),정지윤 ( Jiyun Jung ),남윤정 ( Yun Jung Nam ),김다원 ( Da Won Kim ) 대한내과학회 2018 대한내과학회지 Vol.93 No.6

        Intestinal tuberculosis is an infection of the gastrointestinal tract by the Mycobacterium tuberculosis complex. To the best of our knowledge, solitary intestinal tuberculosis accompanied by intestinal obstruction, particularly in the middle of the small intestine, is extremely rare. We report a case of solitary jejunal tuberculosis in a 49-year-old man with no underlying disease. He was admitted a few days after the onset of diffuse abdominal discomfort. Upon evaluation, we initially considered a malignancy of the distal jejunum with ileus due to the presence of a mass. Therefore, he underwent laparoscopic resection of the small bowel. Unexpectedly, the histologic specimen showed a chronic caseating granulomatous lesion with acid-fast bacilli. Ultimately, he was diagnosed with solitary jejunal tuberculosis. He was successfully treated with anti-tuberculosis drugs without any complications. (Korean J Med 2018;93:556-559)

      • KCI등재

        부신으로 전이된 위장관기질종양 1예

        강현정 ( Hyeon Jeong Kang ),조혜진 ( Hye Jin Cho ),김경현 ( Kyung Hyun Kim ),정미경 ( Mi Kyong Joung ),재욱 ( Jae Uk Shin ),진수신 ( Su Sin Jin ) 대한내과학회 2017 대한내과학회지 Vol.92 No.5

        위장관기질종양에서 다른 장기로의 전이가 없는 부신 단독으로의 전이는 매우 드물지만 발생이 가능하므로 부신에 종양이 있는 경우에 위장관기질종양 치료 병력이 있다면 반드시 이의 전이 가능성에 대해서 고려하여야 한다. 그리고 고위험 위장관기질종양 환자는 병변에 대한 완전 절제술 후에도 재발이 발생할 가능성이 높아서, 재발률을 낮추고 환자의 예후를 향상시키기 위해서 imatinib 보조 치료를 장기간 시행하는 것이 중요하다. 또한 imatinib 치료를 시작한 이후에 잔존 병소에 대해서는 6-12개월 사이에 수술을 시행하여서 imatinib이차 내성에 의한 병변의 재발을 방지해야 하겠다. 저자들은 위에서 발생한 위장관기질종양을 수술적 절제를 시행하고 imatinib을 이용한 보조화학요법을 유지하였음에도 불구하고, 왼쪽 부신에 원격 재발을 일으킨 사례를 국내에서 처음으로 경험하였기에 문헌고찰과 함께 보고하는 바이다. A 56-year-old male with a gastrointestinal stromal tumor (GIST) underwent surgical resection of the tumor. Nine months after surgery, imatinib therapy was initiated because of the discovery of metastatic tumors in the left adrenal gland and in a lymph node of the peritoneum. Seventeen months later, the patient achieved complete remission (CR) and imatinib therapy was continued. However, 48 months after initiation of imatinib therapy, computed tomography scans revealed a left adrenal gland metastasis and the patient underwent left adrenalectomy. Immunohistochemical staining indicated that the spindle-shaped cells of the resected tumor were positive for C-kit, thus confirming metastasis of the GIST. This is the first report from Korea of an adrenal gland metastasis from a GIST. Worldwide, only two such cases have been reported. Here, we describe the first case of a distant recurrence of a GIST in the left adrenal gland after CR had been achieved with the aid of surgical resection and imatinib therapy. (Korean J Med 2017;92:471-475)

      • KCI등재

        복통을 동반한 간포충증 1예

        김완철 ( Wan Chul Kim ),재욱 ( Jae Uk Shin ),진수신 ( Su Sin Jin ) 대한소화기학회 2021 대한소화기학회지 Vol.77 No.1

        Hydatid cysts are caused by an infestation with larval tapeworms of the genus Echinococcus. The disease is endemic in developing countries but has rarely been reported from immigrant workers in Korea. This paper reports a case of hepatic hydatid cyst in a 27-year-old female. She was referred with abdominal pain that had persisted for the past 2 months. The patient was a foreign worker from Mongolia. The physical examination was unremarkable, and blood tests showed peripheral blood eosinophilia and elevated liver enzymes. Abdominal ultrasonography showed a well-circumscribed cystic mass with septation in the liver. A surgical resection was performed for complete removal. After uncomplicated postoperative recovery, the patient was discharged with albendazole 400 mg twice daily. The hydatid cyst is an important disease that should be considered in the differential diagnosis of cystic lesions in the liver, particularly in those who have lived in endemic areas. A correct early diagnosis based on the typical image findings is important for early treatment before the rupture of the cyst, which is associated with low morbidity and mortality. A current surgical resection combined albendazole are effective treatments for hepatic hydatid cysts, associated with low recurrence rates. (Korean J Gastroenterol 2021;77:35-38)

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