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- 저자 : 지현영 ( Hyun Young Ji ) (검색결과 3 건)
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난소 성숙낭성기형종의 악성 변화 진단 관련 지표에 관한 연구
지현영 ( Hyun Young Ji ),김태중 ( Tae Joong Kim ),김민재 ( Min Jae Kim ),이은주 ( Eun Joo Lee ),이유영 ( Yoo Young Lee ),김철중 ( Chul Jung Kim ),최철훈 ( Chel Hun Choi ),이정원 ( Jeong Won Lee ),김병기 ( Byoung Gie Kim ),배덕수 ( 대한산부인과학회 2009 Obstetrics & Gynecology Science Vol.52 No.12
Objective: To evaluate factors for diagnosis of squamous cell carcinoma arising from ovarian mature cystic teratoma and whether squamous cell carcinoma (SCC) antigen, CA125, CA19-9 and CEA is useful for detection of the malignant transformation of mature cystic teratoma of ovary. Methods: From October 1999 to December 2008, 11 patients with malignant transformation arising from ovarian mature cystic teratoma were treated at Departments of Obstetric and Gynecology in Samsung Medical Center. Demographic characteristics, symptoms, sign, preoperative images, stage, mode of therapy and results of follow up were reviewed retrospectively. Results: The incidence of squamous cell carcinoma arising from ovarian mature cystic teratoma was 0.15% (11/7,345) in this hospital. The median age of patients was 60.8 years (range, 48~73 years). The most common preoperative diagnosis is mature cystic teratoma (n=5), followed by malignant transformation of mature cystic teratoma (n=3), colon cancer (n=2), primary epithelial ovarian cancer (n=1). SCC antigen level was elevated in five patients (45.4%) and CA125 was elevated in seven patients (63.6%). Median longitudinal diameter of ovarian tumors was 11.1 cm. All the patients were surgically staged. Conclusion: We should consider women, old aged and had large sized ovarian teratoma, were associated with development of malignant transformation of ovarian mature cystic teratomas, especially squamous cell carcinoma. CEA, CA19-9, and SCC antigen, in addition to CA125, should be used for tumor markers.
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태아 기형의 진단을 위한 태아 자기공명영상과 산전 초음파의 비교
김민재 ( Min Jae Kim ),김하정 ( Ha Jung Kim ),지현영 ( Hyun Young Ji ),서은성 ( Eun Sung Seo ),최석주 ( Suk Joo Choi ),노정래 ( Cheong Rae Roh ),오수영 ( Soo Young Oh ),김종화 ( Jong Hwa Kim ) 대한주산의학회 2008 Perinatology Vol.19 No.3
목적: 태아 기형의 진단에 있어 산전 초음파와 태아 자기공명영상 소견을 산후 진단과 비교하여 그 정확성을 비교하였다. 방법: 2005년부터 2008년 까지 산전 초음파와 자기공명영상을 모두 시행한 41예를 후향적으로 분석하였고, 이 중 출생 후 진단이 확인된 28 예에서 각 진단 방법에 의한 산전 진단 및 최종진단의 연관성에 관하여 분석하였다. 출생 후 진단은 이학적 검사 및 영상의학적 검사, 수술, 부검 등을 통하여 이루어졌다. 결과: 태아 자기공명영상 시행의 가장 흔한 적응증은 중추신경계 기형(n=12)이었으며, 그 외에도 흉강 내 기형(n=5), 복강 내 기형(n=2), 비뇨생식기계 기형(n=3), 두경부 기형(n=4), 기타(n=2)의 경우에 대해 시행되었다. 출생 전후의 진단을 비교시, 태아 자기공명영상의 정확도는 89%로, 71%인 산전 초음파에 비해 우수하였다. 태아 자기공명영상은 중추신경계 기형에 대한 4예 및 비뇨생식기계 기형에 대한 1예와 두경부 기형에 대한 l예에서 보다 정확한 진단 결과를 보였으나, 대조확장의 1예에서는 정확한 진단에 실패하였다. 2 (7.1%)예에서 두 검사에 의한 산전 진단이 모두 부정확하였다. 결론: 태아 자기공명영상은 초음파 검사를 보완하고, 보다 정확한 정보를 제공하며, 특히 태아의 중추신경계, 흉강, 비뇨생식기계 기형 진단 등에 유용한 것으로 나타났다. Purpose: To compare the accuracy of fetal magnetic resonance imaging (MRI) and prenatal ultra-sonography (USG) with postnatal diagnosis for the diagnosis of fetal anomalies. Methods: Retrospective analysis of 41 fetuses who underwent fetal MRI with prenatal USG from 2005 to 2008 was performed. In 28 cases of the total population, the final neonatal diagnosis was also analyzed for the consistency of pre- and postnatal diagnoses for each diagnostic tool. Postnatal diagnosis was confirmed by physical examination, radiographic studies (USG, MRI and/or computed tomography), surgery, and/or autopsy. Results: Mean gestational age at the fetal MRI performed was 26.1±4.7 weeks. The most common indication of the fetal MRI was central nervous system (CNS) anomalies (n=12), followed by thoracic anomalies (n=5), abdominal anomalies (n=2), genitourinary anomalies (n=3), head and neck anomalies (n=4), and others (n=2). When compared with postnatal diagnosis, the accuracy of prental MRI was superior to prenatal USG (89% vs. 71%). The cases with additional accurate diagnosis with using fetal MRI were 4 CNS, 1 genitourinary, and 1 craniofacial anomaly. Of notes, there was a case of enlarged cisterna magna in which prenatal MRI missed the diagnosis. In 2 cases (7.1 %), both imaging studies made an incorrect prenatal diagnoses. Conclusion: Fetal MRI could confirm the USG diagnosis in most cases and provided more accurate diagnosis in some cases of CNS and thoracic, genitourinary system abnormalities. MRI is expected to be a good adjunctive for USG to improve prenatal diagnosis of fetal anomalies.
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임산부의 체질량지수에 따라 산전 부신피질호르몬 치료가 신생아 호흡곤란증후군의 발생에 미치는 영향
조은주 ( Eun Ju Jo ),곽혜민 ( Hye Min Kwak ),지현영 ( Hyun Young Ji ),차현화 ( Hyun Hwa Cha ),최석주 ( Suk Joo Choi ),오수영 ( Soo Young Oh ),노정래 ( Cheong Rae Roh ),김종화 ( Jong Hwa Kim ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.10
Objective To investigate the effects of antenatal corticosteroid (ACS) on incidence of neonatal respiratory distress syndrome (RDS) according to maternal body mass index (BMI). Methods We retrospectively reviewed the medical records of 715 singleton pregnant women who delivered between 24+0 and 34+0 weeks of gestation, from January 1996 to December 2006. Subjects were categorized into three groups according to ACS exposure a nonuser group (n = 244), a single-course group (n = 377) and a multiple-course group (n = 94). Subjects were re-categorized into three groups according to maternal BMI at admission group 1 (BMI < 23.0 kg/m2, n = 234), group 2 (BMI 23.0-24.9 kg/m2, n = 166) and group 3 (BMI ≥ 25.0 kg/m2, n = 315). Univariate and multiple logistic regression analyses were used for the statistical analysis. Results Overall, the incidence of RDS was significantly lower in ACS-user groups than the non-user group, with lowest incidence in the multiple-course group (non-user vs. single-course vs. multiple-course 44.3% vs. 41.1% vs. 11.7%, P < 0.001). The incidence of RDS was not different among the three BMI groups. Multiple logistic regression analysis showed that single- and multiple-course of ACS was significantly associated with reduced incidence of RDS single-course, odds ratio (OR) 0.593, 95% confidence interval (CI) 0.373, 0.942; multiple-course, OR 0.085, 95% CI 0.034, 0.213. However, maternal BMI was not associated with reduced incidence of RDS with different ACS-courses ( P for interaction = 0.690). Conclusion ACS therapy, especially when multiple-course was used, was significantly associated with reduced incidence of RDS, but maternal BMI did not influence its effectiveness.
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