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김남인 ( Kim Nam In ),조윤주 ( Jo Yun Ju ),권계형 ( Kwon Gye Hyeong ),김태헌 ( Kim Tae Heon ),주연호 ( Ju Yeon Ho ),박영숙 ( Park Yeong Sug ) 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<목적> 호산구성 위장관염은 호산구 침윤에 의한 다양한 위장관 증상을 나타내는 비교적 드문 질환으로, 임상의는 산발적으로 경험하고 있다. 아직 원인 및 병리학적 배경은 모르나, 점차 빈도가 증가하고 있어 관심이 모아지고 있다. 이에 저자들은 최근 호산구성 위장관염 3예를 경험하였기에 국내 보고 증례를 분석하여 임상 양상 및 특징을 살펴보았다. <방법> 1970-2003년까지 한국의학연구정보센타를 통해 검색된 호산구성 위장관염 국내보 26예와 2002-2
궤양성 대장염 환자의 대장점막에서 CXC chemokine 유전자의 발현
박영숙 ( Park Yeong Sug ),권계형 ( Kwon Gye Hyeong ),김태헌 ( Kim Tae Heon ),주연호 ( Ju Yeon Ho ),조윤주 ( Jo Yun Ju ) 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<목적> 궤양성 대장염의 병리기전으로 정상적인 염증반응의 감쇠가 이루어지지 못하여 염증이 지속되는 것으로 알려져 있다. TNF-α 혹은 세균에 의한 자극을 한 대장상피세포가 자극이 없는 경우에 비해 CXC chemokine인 IP-10의 mRNA 농도가 증가하고 IP-10 단백의 분비도 증가되는 것으로 보고하여 대장상피세포의 역할이 단순한 환경에 대한 방어막 외에 직접 염증반응에 관여하며 조절기능을 하는 것으로 보고하였다. 그러므로 만성적으로 염증반응이
소화성궤양 환자에서 저용량 clarithromycin 3제요법의 Helicobacter pylori 제균효과
정명아 ( Myeong A Cheong ),김태헌 ( Tae Hun Kim ),박영숙 ( Young Sook Park ),이진혁 ( Jin Hyuk Lee ),주연호 ( Yeon Ho Joo ),최일주 ( Il Ju Choi ) 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
<목적> 우리나라에서는 H. pylori의 첫 치료로 PPI, amoxacillin과 clarithromycin의 3제요법이 추천되고 있다. Clarithromycin의 용량은 500mg을 하루 2회 복용하는 것이 추천되나, 250mg을 하루 2회 복용하는 저용량 Clarithromycin 3제요법의 H. pylori 제균 효과에 대하여는 아직 논란이 있는 실정이다. Omeprazole을 사용한 3제요법에 대한 국내의 보고에서 clarithromycin
김진호,박소연,김명환,박원철,이호정,이성구,주영민,서동완,송병철,민영일,유교상,고진규,한상택,정세라,주연호 대한소화기내시경학회 2000 Clinical Endoscopy Vol.20 No.2
An anomalous pancreaticobiliary ductal union is a rare anomaly occurring in the biliary tract. This anomaly has been implicated as a cause of choledochal cysts, bile duct and gallbladder carcinoma, and recurrent pancreatitis. A case is herein reported of a 63 year-old woman who suffered from gallbladder cancer associated with a choledochal cyst and an anomalous pancreaticobiliary union.
22q11 Deletion Syndrome을 동반한 정신분열병 1예
방수영,김창윤,주연호,서을주,유한욱 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.4
It has been well known that 22q deletion syndrome (22qDS), encompasses several genetic syndromes associated with microdeletions at chromosome 22q11.2 became relatively generally identified in the 1990s through the availability of specialized chromosomal studies, and it includes such syndromes as velocardiofacial syndrome (VCFS), DiGeorge syndrome (DGS), Shprintzen syndrome, CATCH 22. The syndrome is characterized by distinctive dysmorphology, congenital heart disease, athymia, parathyroid disease, other congenital diseases, learning difficulties and various psychiatric illnesses. This syndrome is a common genetic condition often accompanied by mild cognitive impairment. Learning difficulties and anger outburst are also common in adolescence with this syndrome, In addition, a prevalence of major psychiatric disorders in adults' individuals are high, especially schizophrenia, schizoaffective disorder, bipolar disorder and other psychiatric illnesses, including simple or social phobia, depression, obsessive-compulsive disorder. We report a patient with facial dysmorphology, cleft lip and palate, ventricular septal defect, borderline IQ, poor impulse control and psychotic symptoms who was diagnosed schizophrenia and 22qDS by FISH analysis which finds 22q11.2 microdeletion.
담도암 환자에서 담도경적 조직 검사 결과에 영향을 미치는 인자
김명환,박주상,이성구,서동완,민영일,주연호 대한소화기내시경학회 2001 Clinical Endoscopy Vol.22 No.3
Background/Aims: This study analyzed the factors associated with the yield of percutaneous transhepatic cholangioscopic biopsies in patients with bile duct cancer. Methods: One hundred and sixteen patients who had received percutaneous transhepatic cholangioscopy and who had been confirmed as having bile duct cancer were enrolled in this study. Results: When the location of the tumor was divided into intrahepatic (IHD), hilar and common bile duct, the biopsy yield was significantly higher in IHD cancer (93.7%) than in cases of hilar cancer (69.6%) (p$lt;0,05). After a bile duct cancer had been classified as a nodular (n=31), papillary (n=27) or infiltrative type (n=58) upon cholangioscopic findings, the biopsy yields from nodular (96.8%) or papillary types (96,3%) were significantly higher than from infiltrative types (58.6%; p$lt;0.01). However, cholangioscopic classification of bile duct cancer was the only independent factor affecting biopsy yield by multiple logistic regression analysis (p=0,001). The sensitivity of the combination of cholangioscopic biopsy and tumor vessel in overall bile duct cancer, especially in the infiltrative type, was significantly increased when it was compared with that for cholangioscopic biopsies (p$lt;0.01) or for tumor vessels alone (p$lt;0,01). Conclusions: The cholangioscopic classification of bile duct tumors might provide important clues to predict biopsy yield.
이경아,김명환,박주상,이성구,서동완,민영일,유교상,주연호,유지숙 대한소화기내시경학회 2000 Clinical Endoscopy Vol.20 No.4
Lung cancer metastatic to the small intestine is uncommon. Despite the widespread nature of metastases that characterize this carcinoma, symptomatic intestinal metastases are extremely rare, but have been reported as a cause of intestinal obstruction, hemorrhage, malabsorption, and perforation. We have recently encountered two cases with squamous cell lung cancer who underwent endoscopic retrograde cholangiopancreatography for obstructive jaundice. Biopsies obtained from concentric ulcerative mass in the duodenum showed metastatic squamous cell carcinoma in the lymphatics. Histologically, the pulmonary and duodenal lesions were identical and this suggests a lymphatic route of dissemination. This is the report of two cases with obstructive jaundice secondary to duodenal metastasis from primary lung cancer. Metastatic squamous cell carcinoma of the lung to the duodenum should be considered in the differential diagnosis of patients harboring such a malignancy who have obstructive jaundice.