Organoid Engineering for Regenerative Medicine

조승우 한국공업화학회 2022 한국공업화학회 연구논문 초록집 Vol.2022 No.-

부피유지성을 가지는 지방조직의 재생

조승우,김상수,이종원,조현미,최차용,김병수 한국고분자학회 2004 한국고분자학회 학술대회 연구논문 초록집 Vol.2004 No.04

[행복일기 6] 신입 장교의 아찔한 실수

조승우 샘터사 2023 월간 샘터 Vol.643 No.-

Three-Directional Reconstruction of a Massive Perineal Defect after Wide Local Excision of Extramammary Paget’s Disease

조승우,장학,권성택 대한성형외과학회 2016 Archives of Plastic Surgery Vol.43 No.5

Extramammary Paget’s disease (EMPD) is a rare, slow-growing intraepithelial malignancy that mainly involves the genital region, including the vulva, penis, scrotum, perianal, and periurethral areas. Although several treatment options exist, wide local excision with a safe margin is considered the treatment of choice. After resection of the lesion, it is often challenging to reconstruct the defect because defects in the perineal region require adequate volume for protection and are susceptible to infections, which is a particularly significant risk for large defects. We report a case of perivulvar EMPD that was reconstructed with three-directional local flaps after wide excision of the tumor. We covered the defect sequentially using the following 3 flaps: a gracilis myocutaneous flap from the left thigh, a bipedicled V-Y advancement flap from the lower abdomen, and an internal pudendal artery perforator-based island flap from the right buttock. To the best of our knowledge, this report is the first to describe a three-directional approach to extensive perivulvar reconstruction.

초고속 동영상으로부터 인체 동작에 대한 3D 모델 생성

조승우,최승욱,김민석,김계영 한국정보과학회 2022 정보과학회 컴퓨팅의 실제 논문지 Vol.28 No.8

Research on the generation and prediction of 3D models for human motion from videos is a field of active research. In previous researches, a kinematic model is generated by estimating joint coordinates from a normal-speed video, or a 3D motion model of the human body is generated through 3D reconstruction. However, when fast motions such as sports are captured with a normal-speed camera, blurring occurs frequently. As a result, noise is generated during the 3D model generation process, resulting in unnatural results. In this paper, we try to solve this problem by using ultrahigh-speed video. The proposed method combines 3D reconstruction and 3D human pose estimation to generate a 3D model of the dynamic motion of the human body from a single-view ultrahigh-speed video. For the experiment, an ultra-high-speed video was captured at 960fps utilizing PIFu and MotioNet. As a result of the performance evaluation through the experiment, the P2S and Chamber were similar to the existing methods, but the Normal was significantly improved to 0.084cm. 동영상으로부터 인체의 3D 동작 모델 생성 및 예측에 관한 연구가 활발히 이루어지고 있다. 기존에는 평속영상으로부터 관절 좌표를 추정하여 운동학적 모델을 생성하거나, 3D 재구성을 통해 인체의 3D 동작 모델을 생성한다. 하지만 스포츠와 같이 빠른 동작을 평속 카메라로 촬영하였을 때는 흐림 현상이 빈번히 발생한다. 이로 인해 3D 모델 생성 과정에서 잡음이 생성되어 부자연스러운 결과물이 생성된다. 본 논문에서는 초고속영상을 사용하여 이러한 문제를 해결하고자 한다. 제안하는 방법은 3D 재구성과 3D 사람 자세 추정을 결합하여 단일 시점 초고속 동영상으로부터 인체의 역동적인 동작에 대한 3D 모델을 생성한다. 실험을 위하여 초고속 동영상은 960fps로 획득했으며, PIFu와 MotioNet을 활용하였다. 실험을 통한 성능 평가 결과 P2S와 Chamber는 기존의 방법과 유사했지만, Normal은 0.084cm로 현저히 개선되었다.

인간행동 시뮬레이션을 통한 노인주거 피난안전성 검증에 관한 연구

조승우,김경배 대한건축학회 2019 대한건축학회논문집 Vol.35 No.9

Recently as the rapid increasing of the elderly, silver housing has grown up. Though much fire evacuation and safety law, fire accident ismost dangerous problem in our society. So this study is the purpose to analyze evacuation safety in urban silver housing of floor planningby corridor types using human behavior simulation. The methodology of this study is ‘Literature Review’ and ‘Simulation’. This study hasbeen carried out on silver housing’s definition, types, fire safety theory and relation law. To proof evacuation safety, this study measuredescaping time, longest distance, and bottleneck counting using human behavior simulation. This study use game engine simulation program toanalyze 6 corridor types experimental model. As the result of simulation, this study compare between ASET and simulation result. The resultcome down to 3 part. First, double loaded corridor type is the most dangerous on urban silver housing. Second, Safe shelter’s location andnumber cause increasing of escaping time. Lastly escaping time is influenced by behavior of agent, bottle neck strike frequency. 피난 및 화재에 관한 많은 법률이 제정되어있음에도, 노인주거의 화재 사고는 증가하고 있다. 본 연구의 목적은 도심형 노인주거의 피난안전성을 검증하기 위해 복도유형 별 건축계획을 도출하고, 시뮬레이션 분석을 통해 피난에 가장 합리적인 건축계획을 제시하는 것이다. 노인주거의 피난안전을 검증하기 위해 사용한 본 연구의 연구방법론은 문헌연구와 인간행동 시뮬레이션이다. 문헌연구를 통해 노인주거의 정의, 유형을 고찰하고, 일본 건축기준법을 참고하여 피난허용시간을 도출하였다. 또한, 시뮬레이션을 통하여 가상공간 내 유형화된 노인주거 평면계획을 실험하여 피난시간을 도출하였다. 본 연구에서는 피난안전에 가장 합리적인 복도유형을 도출하기 위하여 시뮬레이션 분석을 통해 산출된 피난시간과 문헌연구를 통해 도출된 피난허용시간을 비교 및 검증하였다. 도출된 실험 결과는 다음과 같다. 중복도 유형이 피난허용시간을 초과한 유형으로 나타났으며, 재실자 및 관리자의 행동과 병목현상, 피난처의 수와 편중은 피난시간에 영향을 미치는 것으로 분석되었다.

자가 골수 중간엽줄기세포와 생분해성 고분자 스캐폴드를이용한 조직공학적 인공혈관 제조

조승우,김동익,박희정,임상현,전오주,김수현,김영하,최차용,이민재,김종성,장인성,김병수 대한혈관외과학회 2003 Vascular Specialist International Vol.19 No.2

Biomaterials for the control of stem cell differentiation and cellular reprogramming

조승우 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.0

Stem cell therapeutics have shown great potential for the treatment of incurable diseases, but their therapeutic efficacy needs to be improved by enhancing specific lineage differentiation for efficient tissue regeneration. Direct reprogramming has been highlighted for the generation of tissue-specific cell types, but low efficiency still remains a major challenge. In this presentation, several materials and devices will be introduced to promote neuronal differentiation of stem cells and direct conversion of skin fibroblasts to neuronal lineage cells. In the first part, microfluidic devices and nanoscale patterned substrates for the reconstitution of neural stem cell microenvironments are reported to promote functional neuronal differentiation. In the second part, micro-devices generating external stimulation and brain-specific microenvironment are reported for significantly improving the efficiency of polymer nanoparticle-mediated direct neural conversion.

생활 속의 줄기세포 이야기

조승우 한국생물공학회 2011 BT NEWS Vol.18 No.1

A Systematic Proteome Study of Seed Storage Proteins from Two Soybean Genotypes

조승우,우선희,Soo-Jeong Kwon,Swapan Kumar Roy,Hong Sig Kim,이철원 한국작물학회 2014 Korean journal of crop science Vol.59 No.3

Soybean seed is a good source of plant proteinin human consumables such as baby formula and proteinconcentrate. The seeds contain an abundance of storageproteins, namely β-conglycin and glycinin that account for ~70-80% of the total seed protein content. Proteome profilinghas been proved to be an efficient way that can help usto investigate the seed storage proteins. In the present study,the seeds were removed from the pods and the cotylendonarytissues were separated from the testa for proteome analysisin order to investigate the seed storage proteins. A systematicproteome profiling was conducted through one-dimensionalgel electrophoresis followed by MALDI-TOF-TOF massspectrometry in the seeds (cotyledonary tissue) of soybeangenotypes. Two dimensional gels stained with CBB, a totalof 10 proteins were identified and analyzed using MASCOTsearch engine according to the similarity of sequences withpreviously characterized proteins along with the UniProtdatabase. A total of ten proteins such as glycinin Gy4 precursor,glycinin G3 precursor, glycinin G1 precursor, glycinin chainA2B1a precursor, glycinin chain A2B1a precursor wereidentified in our investigation. However, the glycinin subunitmay be considered to play important roles in soybean breedingand biochemical characterization. In addition, the improvedtechnique will be useful to dissect the genetic control ofglycinin expression in soybean