Regional Bone Loss as a Risk Factor for Distal Radius Fracture in Women under 60 Years Old

정화재,이진명,신헌규,박재형,박세진,고태수,박종현,김유진 대한골다공증학회 2014 Osteoporosis and Sarcopenia Vol.12 No.3

Objectives: Some studies have suggested that lumbar spine and hip bone mineral density (BMD) are not associated with distal radius fractures (DRF), and a few studies have investigated regional BMDs at the fracture site, not just the lumbar or hip. We correlated distal radius BMD with DRF in postmenopausal women <60 years old. Methods: A total of 121 women ≥50 years old with DRF were enrolled in the fracture group, and 72 women without fractures were included as a control group. We measured distal radius BMD in the distal radius contralateral to the fractured bone in the fracture group and that of the lumbar body 5 days after the trauma. BMDs at the distal radius of each group were compared in three age groups (50~59, 60~69, and ≥70 years). Age- and site-specific BMDs were analyzed in each group. Results: No significant differences in the rate of osteoporosis at the distal radius or lumbar spine were observed in patients ≥60 years old. However, BMD and T-score values of the distal radius in female patients were lower than those in controls <60 years old. BMD and T-score values of the distal radius were lower than those of the lumbar spine in the fracture group <60 years old. BMD of the distal radius also carried a higher relative risk. Conclusions: Low BMD of the distal radius was an indicator of regional BMD and could be a sensitive risk factor for DRF in women <60 years.

관절강 내에서 모든 수술 과정을 시행하는 관절경적 전방십자인대 재건술

정화재,Jeong, Hwa-Jae 대한관절경학회 1997 대한관절경학회지 Vol.1 No.1

The all inside anterior cruciate ligament reconstruction technique places an anterior ligament substitutes within two bony sockets rather than hone tunnel. This approach is accomplished through arthroscopic three portal which avoids the surgical exposure and morbidity associated with creating traditional bone tunnel. This technique has several distinct advantages when compared with the traditional ACL reconstruction through the bone tunnels. It offers the surgeon a less morbid method for ACL reconstruction that positions an ACL substitute at the anatomic attachment sites of the original ACL with two bone sockets, obviating the need for traditional bone tunnels. Graft fixation at or near the anatomic attachment points of the original ACL minimizes creep with early range of motion and reduces the abrasive 'wind-shield wipe' motion of the graft which occur with bone plugs positioned inside bone tunnels. The sagittal posterior angle to the tibial socket increases fixation strength to pullout with anterior translation force for the tibia on the femur. This technique is not graft specific and can accomodate any graft in which graft length can be customized to the intraarticular native ACL length.

건강한 한국인의 액와신경의 신경전도에 관한 연구

정화재,오정희 한림대학교의료원 1984 人間科學 Vol.8 No.12

소아 대퇴골 간부 골절에 대한 고찰

정화재,김도영,신주호,정선균 한림대학교의료원 1994 人間科學 Vol.18 No.6

운동이 Prednisolone 투여 골결근에 미치는 영향에 관한 조직화학적 및 미세구조적 연구

鄭和在,吳貞姬 고려대학교 의과대학 1991 고려대 의대 잡지 Vol.28 No.1

Glycogen depletion of type Ⅰ and type Ⅱ muscle fiber was studied during exercise with prednisolone treated rat skeletal muscle. Glycogen content in individual fibers were calculated as optical density of Periodic acid-Schiff(PAS) stain and structural changes were observed under electron microscope. The experimental rats were divided into 6 groups : In the control group, nothing but injection of distilled water was applied. First group was exercised only without prednisolone treatment. Second, third and fourth groups respectively had 5, 10, 15 days of prednisolone treatment with exercise and the fifth group had 30 days of recovery after the completion of 15 days prednisolone treatment with exercise. Glycogen depletion was observed in almost all type Ⅰ fibers during the short term exercise, and in about 90% of Type Ⅱ fibers with prolonged exercise. Glycogen restoration was observed more in type Ⅱ fibers after 30 days rest than in Type Ⅰ fibers. In the ultrasructural observations for rats with 5 days exercise without prednisolone treatment the noticeable findings were the disappearance of A and I bands in the myofibrils of both soleus and gastrocnemius. However, these bands appeared to be gradually increased with the exercise of the muscles and prednisolone injection for 5, 10, 15 days (group 2, 3, 4). In one of the groups exercised for S days(group 1), the glycogen particles were observed much more in the type Ⅱ fibers than type Ⅰ fibers. The glycogen particles of the former, however, decreased successively reaching to the group 4 or 5. And those of the latter were markedly decreased in all groups(group 1-5). In both type Ⅰ and type Ⅱ fibers, most of mitochondria showed electron lucent area (hydrophilic degeneration) with the 30 days rest after the completion of 15 days treatment of prednisolone with exercise. The sarcoplasmic reticulum showing marked dilatation of its cistern was not found in the type The sarcoplasmic reticulum showing marked dilatation of its cistern was not found in the typeⅡ fibers but it was found in many areas of myofibril of the type Ⅰ fibers. From these results, it may suggest that exercise induce the glycogen depletion in prednisolone treated skeletal muscle as well as in normal skeletal muscle in both type Ⅰ and type Ⅱ fibers and it may give some organellar changes in the muscle fibers as mentioned above.

의학교육과 교육평가

정화재 한림대학교의료원 1994 人間科學 Vol.18 No.3

급성 전방십자인대 손상 시 자기공명영상에서 나타나는 골멍과 전방십자인대 손상 정도의 관계

정화재,신헌규,고천석,김장환,Jeong, Hwa-Jae,Shin, Hun-Kyu,Ko, Chun-Suk,Kim, Jang-Hwan 대한관절경학회 2012 대한관절경학회지 Vol.16 No.1

목적: 급성 전방십자인대 손상 환자의 자기공명영상(magnetic resonance imaging, MRI)에서 나타난 골멍의 형태 및 크기와 전방십자인대의 손상 정도와의 관계를 알아보고 골멍의 발자취(footprint)를 조사해 손상기전을 알아보고자 하였다. 대상 및 방법: 급성 전방십자인대 손상 6주 이내의 급성기에 자기공명영상을 촬영하여 골멍이 나타나는 65명을 대상으로 하였다. 골멍의 형태는 Costa-Paz 분류에 따라, 골멍의 크기는 Kornaat의 방식으로 측정하였다. 자기공명영상의 전방십자인대 관상사면영상(anterior cruciate ligament [ACL] oblique coronal view)에서 손상 정도를 등급화 하였다. 결과: Costa-Paz 분류에 따른 대퇴골 외과의 골멍 형태와 전방십자인대 손상 정도의 관계를 알아본 결과, 부분 파열군(1, 2 등급)에서 제2형이 많고, 완전 파열군(3 등급)에서 제3형이 많았다(P=0.037). Kornaat 총 골멍 점수는 전방십자인대 손상 등급에 따라 차이를 보였으며(P=0.014), 손상기전은 축회전 손상(pivot shift injury)이 가장 많았고 편타 외반 손상 (clip valgus injury) 등이 뒤를 이었다. 결론: 급성 전방십자인대 손상 시 골멍의 형태와 크기는 전방십자인대의 손상 정도와 관련이 있었고, 골멍의 발자취를 통해 손상기전을 유추할 수 있어 급성 전방십자인대 손상의 진단 및 치료에 도움이 되리라 사료된다. Purpose: The aim of this retrospective study was to evaluate the relationship between appearance and size of bone bruise and severity of anterior cruciate ligament (ACL) injury with magnetic resonance imaging (MRI), furthermore, to identify the mechanism of ACL injury by analyzing the footprint of bone bruise. Materials and Methods: Sixty-five subjects who was taken an MRI within 6 weeks after acute ACL injury were studied. All MRI showed ACL injury and associated bone bruises. Bone bruises were analyzed using Costa-Paz classification based on appearance and location and also scored using Kornaat bone bruise grading system based on size and location. The severity of the ACL injury was graded using a 4-point system (ie, grade 0-3) with oblique coronal MRI. Results: There was statistically significant correlation between Costa-Paz classification of bone bruises in lateral femoral condyle and grade of ACL injury. There were more type 2 lesions in partial tear group (grade 1, 2), however, type 3 lesions of Costa-Paz classification in complete tear group (P=0.037). Significant positive correlations were observed between Kornaat total bone bruise score and grade of ACL injury (P=0.014). Most common ACL injury mechanism was pivot shift injury. Other mechanisms were clip valgus injury, phantom foot injury, and hyperextension injury. Conclusion: It is highly suggested that appearance and size of bone bruise is related to severity of ACL injury after acute ACL injury. The foot print of bone bruise provides valuable clues to identify ACL injury mechanism.

운동이Prednisolone 투여 골격근에 미치는 영향에 관한 조직화적 및 미세구조적 연구

정화재,오정희 大韓再活醫學會 1991 Annals of Rehabilitation Medicine Vol.15 No.2

테니스 엘보우(외측 상괴염)

정화재 한림대학교의료원 1991 人間科學 Vol.15 No.4

선천성 슬관절 탐구

정화재,이상수,장준동,이창주 한림대학교의료원 1996 人間科學 Vol.20 No.6