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옥순애,정재걸,공경엽,최기영,유은실,이인철,Oak, Soon-Ae,Chung, Jae-Gul,Gong, Gyung-Yub,Choe, Ghee-Young,Yu, Eun-Sil,Lee, In-Chul 대한세포병리학회 1994 대한세포병리학회지 Vol.5 No.2
There has been a marked increase in the utility of aspiration cytology for pathologic diagnosis. It may be applied to any kinds of organs and substitutes surgical biopsy. Be cause of the high risk of complication and difficulties In localization, aspiration cytology in the central nervous system (CNS) has been used with less frequency compared to other sites. However, with the advent of sophisticated imaging instruments, aspiration cytology of lesions in the CNS is being used increasingly. We present cytologic features of brain tumors as well as corresponding histologic findings. Eight types of tumors were aspirated intraoperatively and stained with the Papanicolaou method; 1 anaplastic astrocytoma, 1 glioblastoma multiforme, 1 ependymoma, 1 malignant ependymoma, 1 central neurocytoma, 1 primitive neuroectodermal tumor, 1 benign neurogenic tumor and 1 germinoma. Cytologic features of the CNS neoplasms were quite similar to those of histology except one spindle cell tumor. Reviewing various CNS neoplasms, it appears that cytology may be a useful diagnostic method.
조현이,하승연,정재걸,오영하,정동해,김나래,이종민,이의돈,Cho, Hyun-Yee,Ha, Seung-Yeon,Chung, Jae-Gul,Oh, Young-Ha,Chung, Dong-Hae,Kim, Na-Rae,Lee, Jong-Min,Lee, Eui-Don 대한세포병리학회 2003 대한세포병리학회지 Vol.14 No.2
Signet ring cell carcinoma is a rare type of mucinous adenocarcinoma of the uterine cervix. To the best of our knowledge, there is no report on cytologlc findings of primary signet ring cell carcinoma of the uterine cervix in the literature. Recently, we experienced two cases of signet ring cell carcinoma of the uterine cervix. The finding of characteristic signet ring cells on cervicovaginal smear led to the diagnosis of signet ring cell carcinoma. However, primary signet ring cell carcinoma could not be cytologically distinguished from more common metastatic tumor. Therefore, diagnosis rests upon the recognition of signet ring cells and the absence of signet ring cell carcinoma elsewhere.
이상열,허승호,정재걸,장연규,길승배,Lee, Sang-Youl,Heo, Seung-Ho,Chung, Jae-Gul,Jang, Yeon-Gyu,Gill, Seung-Bae 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.2
A 69-year-old woman presented with right abducent nerve paresis caused by an ectopic pituitary adenoma invading the posterior wall of the sphenoid sinus. The tumor was removed via transsphenoidal approach. The histological diagnosis was invasive pituitary adenoma with bony destruction. The symptom was improved without complication. The authors present a rare case of ectopic pituitary adenoma with a literature review.
미세단백뇨를 동반한 인슐린비의존형 당뇨병 환자에서 신장 병리 소견의 다양성
정윤이(Yun Ey Chung),이기업(Ki Up Lee),박중열(Joong Yeol Park),홍성관(Sung Kwan Hong),강재영(Jae Young Kang),이종수(Jong Soo Lee),오영하(Young Ha Oh),정재걸(Jae Gul Chung),유은실(Eun Sil Yu),박정식(Jung Sik Park) 대한내과학회 1998 대한내과학회지 Vol.55 No.5
N/A Objective: It was suggested that the cause of microalbuminuria is heterogeneous in NIDDM. However, only a few studies are available that investigated the renal pathology in NIDDM patients with microalbuminuria. This study was undertaken to evaluate renal pathology in Korean NIDDM patients with microalbuminuria. Methods: Fifty NIDDM patients with microalbuminuria and without retinopathy were undertaken renal biopsy. Renal pathologic findings were classified as follows' group A, near normal finding; group B, typical diabetic nephropathology; group C, atypical patterns of renal injury (mild glomerular change with disproportionally severe tubulointerstitial lesion, arteriolar hyalinosis or global glomerular sclerosis); group D, non-diabetic renal lesion. Results: Seventeen patients were classified into group A, 19 into group B and 8 into group C. Six patients had non-diabetic renal lesions and they were all confirmed to be IgA nephropathy, Fasting blood sugar and GFR were significantly higher in group B than in group A and group C respectively, and systolic blood pressure was higher in group C than in group A. Conclusion: Renal pathology in microalbuminuric NIDDM patients without retinopathy was heterogeneous. This may explain heterogeneous clinical meaning of microalbuminuria in NIDDM.
증례 : 진성다혈구증에 병발된 사구체간질 증식성 사구체 신염 1예
박철희 ( Cheul Hee Park ),정낙소 ( Nak So Chung ),정우경 ( Woo Kyung Chung ),방수미 ( Soo Mee Bang ),이종호 ( Jong Ho Lee ),정재걸 ( Jae Gul Chung ),이준승 ( Joon Seung Lee ) 대한내과학회 2005 대한내과학회지 Vol.69 No.-
진성다혈구증과 동반한 사구체신염의 병발은 매우 드문 것으로 보고되어 있다. 진성다혈구증에 병발한 사구체간질 증식성 사구체신염의 보고가 있었으나 면역형광 현미경 검사가 없어서 IgA 신증을 배제하지 못하였다. 저자들은 단백뇨 및 비장비대를 주소로 내원한 환자에서 면역형광 현미경검사를 포함한 신생검으로 사구체간질 증식성 사구체신염과 세계보건기구 진단 기준에 따른 진성다혈구증으로 진단된 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. There are only a few reports of glomerulonephritis associated with polycythemia vera (PV). These cases include diffuse mesangial proliferative glomerulonephritis (mesPGN), Henoch-Schonlein purpura nephritis, focal segmental glomerulonephritis and IgA nephropathy. In 1983, Plomley et al. reported on 3 cases of mesPGN in patients with PV for the first time. However the possibility that these cases were IgA nephropathy could not be excluded since there was no data of electron microscopic or immnunofluorescent (IF) study. We report a case of idiopathic mesPGN combined with PV. A 46-year-old male was referred to our hospital because of proteinuria and splenomegaly on his routine medical examination. While undergoing investigation for the proteinuria, the patient was found to have a high hemoglobin (22.3 g/dL) and hematocrit (68.8%) levels. At that time, the urinary protein excretion was 3.0 g in 24 hour. We diagnosed the patient as a case of PV by World Health Organization criteria. The renal biopsy revealed focal mesangial proliferation with expansion of the matrix. On IF study, there was no deposition of IgA, IgG and C3 in the mesangium. (Korean J Med 69:S884-S889, 2005)
고칼슘혈증과 급성신부전으로 발현한 Renal Sarcoidosis
박정식(Jung Sik Park),이상구(Sang Koo Lee),김순배(Soon Bae Kim),박종하(Jong Ha Park),정재걸(Jae Gul Chung),이우제(Woo Je Lee) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.2
We report a case of renal sarcoidosis accompanied by hypercalcemia and renal insufficiency. A 52-year-old woman presented to hospital with nausea, pruri-tus, general weakness and weight loss. Laboratory tests revealed a serum creatinine was 3.6mg/dL, cal-cium ll.lmg/dL(ionized calcium 5.6mg/dL), hemoglobin 10.2g/dL, parathyroid hormone <3.0pg/mL, 24 hour urinary protein 1,127mg/day and 24 hour urinary calcium 489mg/day. Chest X-ray showed normal and both kidneys were within normal size with mild increased echo- genicity on renal ultrasound. Renal biopsy showed interstitial nephritis with mononuclear cell infiltration and mild interstitial fibrosis. Non-caseating granuloma with epitheloid and giant cells were seen. Following corticosteroid therapy, renal function and hypercalcemia were dramatically improved. Within 1 month, calcium level was normal and the creatinine level fell to 2.0mg/dL and subsequently remained stable while corticosteroid was progressively tapered off. She has been followed up for 11 months with normal seum calcium level and the creatinine level of 1.9mg/dL.
특발성 원섬유성 사구체신염 (Fibrillary Glomerulonephritis)
김지훈(Ji Hoon Kim),정해혁(Hae Hyuk Jung),박정식(Jung Sik Park),이상구(Sang Koo Lee),유은실(Eun Sil Yu),장상필(Sang Pil Chang),이준승(Joon Seung Lee),정재걸(Jae Gul Chung) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.3
A 17-year-old girl was admitted to our hospital due to mild generalized edema. Laboratory tests revealed a serum creatinine was 0.7mg/dL, protein/ albumin 6.7/3.5g/dL, cholesterol 190mg/dL, hemoglobin 10.0g/dL, and 24 hour urinary protein 4,40mg/day. Chest X-ray and renal ultrasound were normal. There were no clinical or serologic evidences of para-proteinemia, cryoglobulinemia, light chain disease or systemic lupus erythematosus. Renal biopsy showed membranoproliferative glomerulonephritis-like pattern with lobular accentuation, hypercellularity and diffuse GBM thickening by light microscope. Congo red stain-ing was negative. Granular IgG and C3 deposits were found along the glomerular capillary wall and mesangium by immunofluorescence microscope. Ultrastruc-turally, abundant subendothelial and mesangial fibril- lary deposits were found associated with thickening and wrinkling of GBM. These fibrils, measured about 20-30nm in diameter, were nonbranching and ran- domly arranged without either periodicity or an organized structure. These findings were compatible with those of fibrillary glomerulonephritis. Thus we report a case of idiopathic fibrillary glomerulonephritis, which is a rare cause of nephrotic syndrome.