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정이조,이태연,오영림,이태화,이천준,김원규 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-
The aim of this retrospective study was to evaluate the efficacy and safety of laparoscopic assisted vaginal supracervical hysterectomy for treatment of uterine myoma and/or adenomyosis patients to compare perioperative results of laparoscopic assiated vaginal supracervical hysterectomy with those of laparoscopic assisted vaginal hysterectomy. We reviewed our 4-years experience with laparoscopic assiated vaginal supracervical hysterectomy performed at Gospel Hospital Kosin University, Busan, Korea between December 2008 and June 2012. A group of 38 patients of uterine myoma and/or adenomyosis who underwent laparoscopic assiated vaginal supracervical hysterectomy was compared with a group of 40 patients who underwent laparoscopic assisted vaginal hysterectomy. The similarities of patient characteristics were analyzed with t-test, X2-testor Fisher` sexacttest. Surgical characteristics and complications wereanalyzed with ANCOVA (analysis of covariance), Logistic regression analysis. Spearman correlation coefficient were used for correlation analysis. Patients characteristics undergoing laparoscopic assiated vaginal supracervical hysterectomy showed lower BMI (22.53 kg/m2 vs 24.43 kg/m2, p=0.0084) and less prior surgery history (7 vs 17, p=0.0213). Surgical chatacteristics undergoing laparoscopic assiated vaginal supracervical hysterectomy showed significantly shorter hospital stays (7.03 days vs 9.20 days, p=0.0015), less blood loss (397.40 ml vs 596.30 ml, p=0.0057) and lighter uterus weight (183.90gm vs 278.00 gm, p=0.0010). Surgical chatacteristics showed shorter hospital stays and less blood loss in laparoscopic assiated vaginal supracervical hysterectomy group than laparoscopic assisted vaginal hysterectomy group. There are no major post-operative complications in both laparoscopic assiated vaginal supracervical hysterectomy and laparoscopic assisted vaginal hysterectomy groups. Based on our results, laparoscopic assisted vaginal supracervical hysterectomy proved to be a useful method for treatment of uterine myoma and/or adenomyosis patients who wants to preserve cervix of uterus, not in the case of huge size myoma and severe adhesion.
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이태연,정이조,이천준,김흥열,김성한,김원규 대한산부인과학회 2013 Obstetrics & Gynecology Science Vol.56 No.1
Objective The aim of this retrospective study is to evaluate the efficacy of adjuvant chemotherapy following radical hysterectomy for intermediate risk stage IB cervical cancer. Methods From January 1993 to December 2007, a total of 100 patients of stage IB were enrolled in this study who had at least two of the following three intermediate risk factors (deep stromal invasion, lymphovascular space involvement, and large tumor size) after radical hysterectomy and all patients had no high risk factors and no radiotherapy. Of these patients, 22 patients had surgery only and 78 patients had cisplatin-based combination chemotherapy as adjuvant therapy postoperatively to improve survival. Kaplan-Meier survival curves and Cox’s proportional-hazards regression model and log-rank test were used for survival analysis and to estimate the impact of prognostic factors on survival. Results The mean age was 52 years (range, 28 to 76 years). The overall survival rate of all intermediate tumors are 92% (92/100). Surgery only group is 81.8% (18/22) and adjuvant chemotherapy group is 94.9% (74/78). Comparison of survival between two groups revealed significant statistical difference in both univariant and multivariant survival analysis (P<0.05). The main toxicities of adjuvant chemotherapy were bone marrow suppression (18%), nausea and vomiting (5.2%) and alopecia in etoposide-cisplatin chemotherapy group (100%) but most side effects of postoperative adjuvant chemotherapy were transient, reversible and within acceptable limits to all patients. Conclusion Cisplatin based combined adjuvant chemotherapy for intermediate risk tumors after radical hysterectomy is promising with significant improvement of overall survival and with acceptable toxicity profile.
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김은택,옥희재,이태연,정이조,오영림,김흥열,김원규,김성한,이태화 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-
Antiphospholipid syndrome (APS) is an autoimmune disorder and it refers to groups of clinical symptoms and signs caused by antiphospholipid antibodies (aPLs). Recurrent miscarriage, early delivery, oligohydramnios, prematurity, intrauterine growth restriction (IUGR), fetal distress, fetal or neonatal thrombosis, pre-eclampsia/eclampsia, HELLP syndrome, arterial or venous thrombosis and placental insufficiency are the most severe APS-related complication for pregnant women. This is report that a case of hemolytic anemia during postpartum period associated and APS with a brief review of the liter ature Key Words: Antiphospholipid syndrome, Hemolytic anemia, Pregnancy.
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