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한국인 뇌졸중 예측모형에 의한 뇌졸중 10년 발생 위험도와 경동맥 내중막 두께의 관련성
정보우,손효경,양진훈,이화평,이채용 대한신경과학회 2012 대한신경과학회지 Vol.30 No.4
Background: Both carotid intima-media thickness (IMT) and global risk score of cardiovascular disease were independent risk factors of stroke and heart disease. We assessed the correlation between the 10-year risk of Korean Stroke Risk Prediction model (KSRP) and carotid intima-media thickness. Additionally, from a perspective of carotid IMT measurement following KSRP risk stratification, we analyzed the difference of carotid IMT and plaque according to the KSRP risk strata. Methods: Subjects were 282 persons who visited one hospital for the screening of stroke. The 10-year risk was calculated automatically based on the equation of KSRP model. The maximal carotid IMT and the plaque were adopted as the study variables. The sensitivity and the positive predictive value of the KSRP risk categories were calculated. Results: The correlation coefficient between the KSRP risk and the maximal carotid IMT was 0.29 (p<0.01). The mean (±standard deviation) of KSRP risk of the group with carotid plaque was statistically significantly higher, 5.3 (±4.1), than that of the group without plaque, 3.3 (±3.1) (p≤0.01). The sensitivity of the risk stratum with more than 6% of KSRP risk for the plaque was 28.2%. The positive predictive value of the above cut-point was 48.8%. Conclusions: The 6% of KSRP risk may be considered as the beginning point of intermediate risk stratum to recommend the carotid ultrasonography. However, generalization needs further studies for various populations.
광흡수층 적용을 위한 PLD용 Cu<sub>2</sub>ZnSnSe<sub>4</sub> 타겟 제조와 증착 박막의 특성
정운화(Jung, Woon-hwa),라흐멧 아드히 위보우(Rachmat, Adhi Wibowo),김규호(Kim, Kyoo-ho) 한국신재생에너지학회 2009 한국신재생에너지학회 학술대회논문집 Vol.2009 No.06
Cu₂ZnSnSe₄(CZTSe) is one of the promising materials for the solar cell due to its abundant availability in the nature. In this study, we report the fabrication of CZTSe thin film by Pulsed Laser Deposition(PLD) method using quaternary compound target on sodalime glass substrate. The quaternary CZTSe compound target was synthesized by solid state reaction method using elemental powders of Cu, Zn, Sn and Se. Powders were milled in high purity ethanol using zirconia ball with mixed size of 1 and 3 mm at the same proportions for 72 hours milling time. The structural, chemical and mechanical properties of the synthesized CZTSe powders were investigated prior to the deposition process. The CZTSe compound powder, and 500?C of sintering temperature shows the best properties for PLD target. Results show that the as-deposited CZTSe thin films with the precursors by PLD have a composition near-stoichiometric.
박성파,정보우,서정규 慶北大學校 醫科大學 1995 慶北醫大誌 Vol.36 No.2
목적 : 뇌졸중 환자에게 경두개적 자기자극(transcranial magnetic stimulation, TCMS)으로 얻은 운동유발전위(motor evoked potential, MEP)가 뇌졸중에 의한 운동기능의 장애를 반영하고 그 기능의 회복을 예측하는데 도움을 줄 것인지 알아보고자 하였다. 대상 및 방법 : 뇌졸중 환자 27례에 TCMS를 시행하여 얻어진 MEP를 대조군 22례와 비교하고 아울러 초기 및 추적검사를 시행하여 그 성적을 서로 비교하였다. 결과 : 환자군의 중추 운동 전도시간(central motor conduction time, CMCT)은 초기와 추적검사에서 모두 병변측이 건측에 비해, 그리고 병변측이 대조군에 비해 유의하게 증가되었으며, 병변측에서는 초기검사의 CMCT가 추적검사의 CMCT 비해 유의하게 증가되었다. 피질 MEP의 무반응은 환자군의 병변측에서 초기검사의 48%, 추적검사의 26%에서 각각 관찰되었으나 대조군 및 환자군의 건측에서는 없었다. 환자군의 초기 및 추적검사 모두에서 MEP의 grade가 증가할수록 근력은 유의하게 감소되었으며 초기에 근력마비가 심하거나 피질 MEP가 무반응인 환자군에서는 추적검사에서도 근력 회복의 예후가 불량하였다. 결론 : 뇌졸중 환자에서 TCMS에 의한 MEP는 뇌졸중에 의한 운동기능의 장애를 정량적으로 평가하고, 뇌졸중 후 운동기능의 회복을 예측하는데 도움을 줄 것이라 사료된다. This study was performed to know whether motor evoked potentials(MEPs) through transcranial magnetic stimulation(TCMS) in stroke patients will reflect the motor dysfunction of stroke, and aid us to predict the functional recovery after stroke. MEPs of 27 stroke patients performing TCMS were compared with those of 22 normal controls, according to the initial and follow-up states of stroke. Central motor conduction time(CMCT) was significantly increased in the lesion side of patient group compared with the sound side of patient group or both sides of control group. At the lesion side of patient group, the CMCT was significantly increased in the initital state compared with follow-up state. No response of cortical MEPs was seen in 48% of patients at the initial lesion side, and 26% at follow-up lesion side, but not in patients at the sound side and in controls at both sides. The increase of MEP grade was significantly correlated to the decrease of muscle strength. Patients with severe motor weakness or no response of cortical MEPs in the initial state also had a poor functional recovery of muscle strength in follow-up state. In conclusion, MEPs using TCMS in stroke patients is useful for quantitative evaluation of the motor dysfunction in stroke, and aid us to predict the functional recovery after stroke.