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      • 기획의도로 보는 몇 개의 3·1운동 전시

        정명아 대한민국역사박물관 2019 현대사와 박물관 Vol.2 No.-

        본 글에서는 3·1운동과 임시정부 탄생 100주년을 기념하여 열린 많은 전시 중 주목할 만한 4개의 전시를 그 기획의도를 중심으로 살펴보았다. 대한민국역사박물관에서는 진정한 의미의 한국현대사의 시작이라고 할 수 있는 3·1운동과 임시정부수립에 대하여 서로 다른 3개의 주제를 동시에 선보였다. 서울역사박물관에서는 서울과 평양 두 도시에서 일어난 3·1운동을 도시사적 관점에서 장소성에 천착하여 전시하였다. 독립기념관은 3·1운동 주제관인 “겨레의 함성관”을 전면 개편하면서 선열들의 독립정신을 ‘국민’들에게 강렬하게 보여주었다. 한편 문화재청에서는 서대문형무소역사관 옥사를 전시실 삼아 항일 등록문화재들을 전시하였다. 각각의 전시들은 같은 3·1운동을 주제로 하지만 주최기관의 정체성에서 기인하는 특징을 흥미롭게 보여주고 있었다.

      • 세정방법에 따른 국소마취제 이온도입의 효율과 편안감 비교

        정명아,송인영,이재형,Jeong, Myung-A,Song, In-Yong,Lee, Jae-Hyoung 대한물리치료학회 2006 대한물리치료학회지 Vol.18 No.4

        Purpose: The purpose of this study was to determined that the efficacy and comfort of iontophoretic transdermal delivery of lidocaine by comparison of local anesthetic duration, sensory threshold, pain threshold and pain tolerance levels according to four different cleansing regimes. Methods: Forty healthy volunteers were randomly assigned to four groups; oil cleansing group, lotion cleansing group, solution cleansing group and alcohol cleansing group. All subjects were received lidocaine iontophoresis on the forearm using direct current with 4 mA for 10 minutes. All subjects were measured the duration of local anesthesia after lidocaine iontophoresis, also evaluated the sensory threshold, pain threshold and pain tolerance level during iontophoresis. For comparisons of the efficacy and the sensory characteristics of iontophoresis within the groups, an one-way ANOVA was used. Results: The duration of local anesthesia were found significant difference between groups (p<0.001). The anesthetic duration in solution and alcohol cleansing groups were significantly longer than oil and lotion cleansing group by post hoc (p<0.05). Statistically significant difference were noted in respect to all sensory characteristics such as sensory threshold, pain threshold and pain tolerance between groups (p<0.001). The sensory threshold in solution and alcohol cleansing group were significantly lower than oil and lotion cleansing group by post hoc using Duncan multiple range test (p<0.05). The pain threshold and pain tolerance in solution and alcohol cleansing group were significantly higher than oil and lotion cleansing group by post hoc (p<0.05). Conclusion: These results demonstrated that cleansing regimes have affected the efficacy and discomfort of iontophoretic transdermal delivery of lidocaine. These findings indicate that cleansing agents without oil ingredient contributed to more comfort, and more successful achievement of the iontophoretic transdermal delivery.

      • KCI등재

        Hypocholesterolemic effects of Curcuma longa L. with Nelumbo nucifera leaf in an in vitro model and a high cholesterol diet-induced hypercholesterolemic mouse model

        정명아,이선영,한슬희,홍지애,나주련,이준열,김영재,김선오 한국통합생물학회 2015 Animal cells and systems Vol.19 No.2

        Hypercholesterolemia is one of the well-established risk factors for cardiovascular mortality and morbidity in coronary heart disease. The present study was designed to investigate the effects of different types of extracts (aqueous, 20%-, and 80% ethanol) of Nelumbo nucifera leaf (NL) and Curcuma Longa L. (CL) on hypercholesterolemia in in vitro and in vivo models. Our results in in vitro experiments showed that treatment with various extracts of both NL and CL dose-dependently inhibited lipid accumulation and total cholesterol content. The 20% ethanol extract of NL (NL20E) and the aqueous extract of CL (CLW) showed the highest activity. The in vivo experimental group was fed a high cholesterol diet (HCD) with oral administration of NL20E, CLW, or a mixture of NL20E with CLW(NC; mixed equal ratio) for 8 weeks. The oral administration of NL20E, CLW, and NC (100 or 300 mg/kg/day) resulted in the suppression of the levels of serum total cholesterol (TC), low-density lipoprotein (LDL)-cholesterol, liver lipid level, glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), atherogenic index (AI), cardiac risk factor (CRF), cholesteryl ester transfer protein (CETP), HMG-CoA reductase, and thiobarbituric acid-reactive substances (TBARS). Similarly, the NL20E, CLW, and NC extracts elevated high-density lipoprotein (HDL) cholesterol levels and lecithin cholesterol acyltransferase (LCAT) activity. Furthermore, NC showed a remarkable hypocholesterolemic effect by decreasing the levels of hepatic TC, AI, LDL cholesterol, HMG-CoA reductase, and CRE and by increasing the levels of HDL cholesterol. Thus, the results of this study indicate that the NC has combined hypocholesterolemic effects that block lipid accumulation, thus preventing hypercholesterolemia.

      • KCI등재후보

        우측 수신증을 동반한 골반내 방선균증 1예

        정명아,서유승,양진수,박준섭,윤진훈,이중건,이준승,이영규,김동희,조성범,주종은 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.2

        Pelvic actinomycosis is a chronic granulomatous suppurative disease caused by an anaerobic grampositive organism Actinomyces israelii. It is com-monly associated with an intrauterine device(IUD) and can mimick pelvic or intra-abdominal malignant neoplasm. Ureteral obstruction leading to hydronephrosis is a rare complication of tubo-ovarian abscess. We experienced a case of hydronephrosis as a complication of pelvic actinomycotic abscess. The patient was a 46-year-old women presenting with fever and right flank pain. Leukocytosis and pyuria were present and a hydronephrosis was diagnosed by intravenous pyelography. Ultrasonography and a computerised tomography revealed a mass in right adnexum compressing the right ureter. Removal of retroperitoneal abscess and salphingo-oophorectomy were done and the diagnosis of actinomycosis was made by pathologic finding of resected mass. Postoperatively, the patient was treated with second-generation cephalosporin successfully. (Korean J Nephrol 2002;21(2):337-340)

      • KCI등재

        마황 에탄올추출물의 Tyrosinase 활성 억제 및 Melanin 생성 억제 효과

        정명아,오수정 한국피부과학연구원 2014 대한피부미용학회지 Vol.12 No.4

        This study observed the effects of Ephedra sinica (E. sinica ) ethanol extract in SK-MEL-2 cells ontyrosinase activity and melanin generation to identify its whitening activity and searched for changes inthe protein expression of tyrosinase, TRP-1 and TRP-2 which are involved in melanin synthesis. Also,α-MSH, a melanin-stimulating enzyme was applied to skin to induce hyperpigmentation and to identifythe skin whitening effect. The following results were obtained. As a result of measuring its tyrosinaseinhibitory activity in vitro , it showed good inhibitory rates depending on concentration. When its effect ontyrosinase activity and melanin generation in SK-MEL-2 cell was analysed, tyrosinase activity decreased ata concentration of 50 ㎍/mL and with arbutin at 82.2%, and tyrosinase activity decreased 70.4% in E. sinicaethanol extract. As a result of measuring melanin generation, arbutin was inhibited 83.6% in 50 ㎍/mL ,and 64% of E. sinica ethanol extract inhibited melanin. In investigating the effect of tyrosinase, TRP-1 andTRP-2 on protein expression in hyperpigmentation by α-MSH using western blot, E. sinica ethanol extractmade the expression of tyrosinase and TRP2 decrease more significantly than arbutin. Therefore, E. sinicaethanol extract showed good effects in inhibiting tyrosinase activity and melanin generation in SK-MEL-2cells, and inhibited melanin synthesis through inhibition of gene expression. Also, it effectively decreasedthe generation of tyrosinase and melanin increased by α-MSH. Based on the results above, it is suggestedthat E. sinica can be developed as a natural skin care material for use in whitening.

      • KCI등재

        4계절 관상용 옥상정원을 활용한 원예활동이 유아의 창의적 사고력에 미치는 영향

        정명,제의숙,이상미,이부영 한국인간·식물·환경학회 2014 인간식물환경학회지 Vol.17 No.1

        본 연구는 4계절 관상용 옥상정원을 활용한 원예활동 프로그램이 유아의 지적발달과 사고력 지수에 미치는 영향을 알아보고자 만 5세 유아 47명중 원예활동에 참여한 실험군 26명과 원예활동에 참여하지 않은 대조군 21명을 대상으로 2013년 5월부터 9월까지 주 1회 총 15회기 실행되었다. 실험 결과 지적발달은 실험군과 대조군 모두 원예활동 프로그램 후에 통계적으로 유의하게 향상되었으나(p=0.023, p=0.016) 실험군의 지적발달이 대조군보다 통계적으로 유의하게 높았다. 지적발달은 유아의 자연발달적 성장과정에서 자연스럽게 이루어지기 때문에 실험군과 대조군 모두 변화를 가져왔으나 원예활동을 수행한 실험군이 더욱 높은 값을 가진 것으로 보아 원예활동이 지적발달에 영향을 주었을 것으로 판단된다. 창의적 사고력 지수는 치료군과 대조군 모두 결과 값은 향상되었지만 통계적으로 유의한 변화는 보이지 않았다. 이는 15주의 연구기간이 사고력의 유의미한 변화를 갖기에는 짧았을 것으로 판단된다. 이러한 결과를 통하여 4계절 관상용 옥상정원을 활용한 원예활동이 유아의 지적발달에 영향을 주는 것으로 판단할 수 있으며, 4계절 관상용 옥상정원을 활용한 다양한 원예활동 프로그램이 개발되어지기를 기대한다. The purpose of this study was to investigate the effect of a horticultural activity program focused on four-season ornamental rooftop garden on both mental development and intelligence quotient of preschoolers. Forty seven preschoolers were participated in this experiment. Experimental group of 26 members were subjected to do the horticultural activity program and 21 members of the control group were not applied with the program. This study was performed once a week for 15 times from May 2013 to September 2013. As a result, mental development of both experimental and control groups were significantly improved (P=0.023, P=0.016) after the horticultural activity program, however improvement of the experimental group was higher than that of the control group. Accordingly, though mental development of both groups was improved as preschoolers grow, horticultural activity program was turned out to be effective in mental development of preschoolers. The intelligence quotient was also improved in both groups, but it was not statistically significant. Accordingly, we speculated that 15 weeks of research duration was not enough to give significant differences in thinking ability. In this study, we concluded that applying horticultural activity program using four-season ornamental rooftop garden to preschoolers was turned out to be effective for improving the mental development of them. Further more various horticultural programs using four-season ornamental rooftop gardens should be developed.

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