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      • 위 유암종의 임상병리학적 특징에 대한 후향적 연구

        장정문,공성호,윤홍만,안혜성,이혁준,윤원재,김상균,양한광,이건욱,Jang, Jeong-Moon,Kong, Seong-Ho,Yoon, Hong-Man,Ahn, Hye-Seong,Lee, Hyuk-Joon,Yoon, Won-Jae,Kim, Sang-Kyoon,Yang, Han-Kwang,Lee, Kuhn-Uk 대한위암학회 2009 대한위암학회지 Vol.9 No.4

        목적: 위 유암종의 임상병리학적 특성과 치료방법 및 예후 등을 분석하였다. 대상 및 방법: 1996년부터 2006년까지 본원에서 치료받았던 18명을 대상으로, 의무기록을 이용한 후향적 연구를 통해 Rindi 분류에 의해 구분하여, 기존의 보고와 임상병리학적 특성 및 치료, 생존율을 비교 분석하였다. 결과: Type I은 8명, type III가 10명이었으며 type II는 없었다. 평균발생 연령은 type I이 47.75세, type III는 57.90세였고, type I은 남자 4명, 여자 4명으로 성비가 1:1이었으나 type III는 남자 7명, 여자 3 명으로 남자에서 많았다. Type I에서도 단발성인 경우가 4예가 있었으며, 1예를 제외하고는 점막 또는 점막하층에 국한되어 있고, 림프절 전이나 원격전이는 없었다. Type III는 병변의 침습성에 관계없이 모두 국소림프절 전이 또는 원격 전이가 있었다. 진단 시 원격전이가 없었던 13명 중 5예에서 내시경적 절제술, 8예에선 수술이 시행되었으며 5년 생존율은 92.3%였다. 원격 전이가 있었던 5예는 평균 생존 기간이 22개월로 이 중 고식적 수술을 시행 받은 3예의 중위 생존 기간은 24개월이었다(95%, ${\pm}6.52$). 결론: 기존의 Rindi 분류법과 비교하여 보았을 때, 본 연구 결과 빈도에 있어서 type III가 type I보다 흔하였다. 또한 type I 유암종에 있어서 평균연령이 낮고, 단발성 종양이 절반 정도를 차지하며, 악성빈혈이 동반되지 않았던 점 등에서 서구와는 다른 특징이 관찰되었다. Purpose: We wanted to analyze the clinicopathologic characteristics of patients with gastric carcinoid tumor, which is a rare gastric tumor (less than 2% of all gastric tumors). Materials and Methods: We reviewed all the carcinoid patients who were treated from 1996 to 2006. The clinicopathologic characteristics, the treatment modalities and the survival rates were retrospectively analysed. Results: There were 8 type I patients and 10 type III patients, but there were no type II patients. The mean age of onset for type I was 47.75 years and that for type III was 57.90 years. More type III patients were female, but the gender ratio of type I patients was equal at a ratio of 1:1. There were 4 cases of solitary tumor, which were all T1 except for one case, and there was neither distant metastasis nor lymph node involvement for the type T1 cases. In the 13 patients who had no metastasis, 5 underwent endoscopic mucosal resection and 8 underwent surgery, and their combined 5 year survival rate was 92.3%. For the 5 cases who had metastastses, their mean survival was 22 months and especially, 3 of them underwent palliative surgery and their median survival were 24 months (95%, ${\pm}6.52$). Conclusion: Higher incidence of type III gastric carcinoid tumor and less multiplicity in type I gastric tumor were identified in our study compared with previous reports. For the type III cases, there were some noteable differences compared with the Western country's survival rate for the patients who underwent palliative surgery, so physicians must pay close attention to the definite clinicopathologic characteristics of gastric carcinoid patients.

      • KCI등재

        현재의 국내 응급의료체계에서 중증외상환자의 이송 지연

        정경원 ( Kyoung Won Jung ),장정문 ( Jeong Moon Jang ),김지영 ( Ji Young Kim ),백숙자 ( Suk Ja Baek ),송서영 ( Seo Young Song ),강찬숙 ( Chan Suk Gang ),이국종 ( Kug Jong Lee ) 대한외상학회 2011 大韓外傷學會誌 Vol.24 No.1

        Purpose: Major trauma patients should be transferred to a definitive care facility as early as possible because prompt management will prevent death. This study was designed to discover the obstacles leading to delayed transfers under the current emergency medical system in Korea and whether there are any negative outcomes associated with conducting procedures at primary care hospitals prior to transferring patients to higher levels of care. Methods: The medical records of major trauma patients with an Injury Severity Score above 15 within the past year were reviewed. Patients were divided three groups as follows: (A) came directly to our emergency center, (B) were transferred without CT or MRI scan at the primary care hospital and (C) transferred with CT or MRI scans. The transfer time of each group were compared and analyzed statistically. Additionally, the number and type of imaging performed at the primary care hospital were analyzed. Results: All qualified patients (n=276) were enrolled in this study: 121 patients in group A; 104 in group B; 51 in group C. There was a statistically significant difference in the transfer time between the three groups (pvalue< 0.001), and 79 (28.6%) were transferred to an emergency medical center within one hour. In group C, CT or MRI scans were performed an average of 1.86 times at the primary care hospital, and the median transfer time was 4 hours 5 minutes. Conclusion: Only 28.6% of the cases in the study arrived within the golden hour at a definitive care facility. Such delays are in part the result of prolonged times at the primary care hospital for radiologic examinations, such as CT or MRI scans. Major multiple trauma patients should be transferred to a definitive care facility directly or as soon as the primary survey and the resuscitation of Advanced Trauma Life Support guideline are completed at the primary care hospital. (J Korean Soc Traumatol 2011;24:25-30)

      • SCOPUSKCI등재

        상부위장관의 Kaposi 육종 1예

        정인식,이강,김선명,박두호,김상우,양영상,장정 대한소화기학회 1999 대한소화기학회지 Vol.34 No.4

        We experienced a 29-year-old woman, who was negative for human immunodeficiency virus (HIV) antibodies and developed Kaposi's sarcoma. It infiltrated into generalized-skin, stomach, duodenum, lung and ureter. She had received kidney transplantation for lupus nephritis followed by the immunosuppression with cyclosporin and deflazacort. Reduction of the immunosuppressive therapy with chemotherapy led to a remission of Kaposi's sarcoma without development of tranplant rejection.

      • SCOPUSKCI등재

        소장폐색을 일으킨 Phytobezoar 2예

        박선희,최규용,정인식,김성수,이강,김명철,선희식,이창돈,안창혁,채현석,장정,방춘상,태현정 대한소화기내시경학회 2001 Clinical Endoscopy Vol.22 No.3

        Phytobezoars are the most common type of bezoars composed of nondigestible food material. They are usually formed in stomach and do not migrate to the other intestinal tract. Recently, we experienced two cases of small bowel phytobezoars resulting in obstruction. The first case is a 72-year-old male patient who had no previous history of surgery. He had poor dentition, and the history of eating dry persimmons 20 days before the onset of symptoms. The phytobezoar (4x3cm) obstructed the terminal ileum. Colonoscopic removal was performed successfully. The second case is a 45-year-old male patient undergone previous vagotomy and pyloroplasty for duodenal ulcer perforation. He had a huge phytobezoar (10 X 6 cm) in stornach, which was treated by endoscopic removal. After incomplete endoscopic treatment, it moved into the proximal jejunum and obstructed the lumen. It was removed by operation.

      • SCOPUSKCI등재

        생선회를 먹은후 십이지장 벽에 박힌 쇠바늘의 내시경적 제거

        한혜원,박선희,최규용,김진일,정인식,김성수,이강,김명철,선희식,이창돈,채현석,장정,방춘상,강형주 대한소화기내시경학회 2001 Clinical Endoscopy Vol.22 No.3

        Foreign bodies in the stomach and duodenum are usually accidentally swallowed by children, mentally ill patients, alcoholics, or persons with dentures. Swallowed foreign bodies are usually asymptomatic, and moved down the alimentary tract to be passed spontaneously without discomfort. There had been reported many kinds of foreign bodies, for example, metal fragments, fish bones and so on. A metal thread, which looks like a fishing hook in gastrointestinal tract as a foreign body, has never been reported in humans. A 62-year-old male patient was admitted due to abdominal discomfort for five days after eating raw fish. We performed gastroduodenoscopy and could find a thread penetrating to the anterior wall of duodenal bulb. It was removed by biopsy forcep. Herein, we report a case of a metal thread in duodenal bulb, which looked like a fishing hook.

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