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      • KCI등재후보

        신결핵의 임상적 고찰

        백혜진(Hye Jin Baeg),김계영(Kae Young Kim),채동완(Dong Ywan Chae),이영천(Young Chun Lee),최문기(Moon Gi Choi),장연복(Yeon Bog Jang),오하영(Ha Young Oh),박정식(Jung Sik Park) 대한내과학회 1991 대한내과학회지 Vol.40 No.3

        Tuberculosis is one of the major infectious disease in Korea, despite its prevalence has been falling. In renal Tuberculosis, there are considerable complications at the time of diagnosis, because of the long duration from exposure to onset of symptoms, which are usually non- specific. In spite of antituberculous chemotherapy, complications may progress and cause obstructive uropathy. In order to evaluate the clinical characteristics of the renal tuberculosis, we reviewed 70 cases of renal tuber- culosis who were admitted to the Hallym University haspital between January 1984 and December 1988, and follwing results were obtained. 1) Renal tuberculosis was predominent in 4th and 5th decades, average age was 39.8 years and males predominated in 1.8:l. 2) The most common presenting symptom was gross hematuria (45.7%), the flank pain, dysuria, nocturia, frequency and fever as a constitutional symptoms in that order. 3) Abnormal findings of urinanalysis were observed in 82.9% of cases and azotemia was found in 25.7%. Asymptomatic urinary abnormality was noted in 25.7%. 4) The positive findings of urine AFB staining in 27.1%,, positive urine AFB culture 5.7%, and 34.3% of cases showed characteristic histopathologic findings. Abnormal urographic findings were seen in 98.5%, and the left kidney was affected predominently (41.5%). 5) Previous extrarenal tuberculosis was noted in 42. 3% and its average duration was 9.3 years. Active extrarenal tuberculosis was associated in 14.3% of cases. 6) The most common complication was hydronephrosis and hydroureter (44.3%), then stone, and secondary infection in that order. 7) Among 6 azotemic patients who were followed more than 3 months after treatment, serum creatinine clearence level was decreased in 5 patients.

      • KCI등재후보

        당뇨병성 케톤산증의 임상적 고찰

        함상수 ( Ham Sang Su ),김욱 ( Kim Ug ),박신성 ( Park Sin Seong ),서영일 ( Seo Yeong Il ),임성희 ( Im Seong Hui ),김병태 ( Kim Byeong Tae ),최문기 ( Choe Mun Gi ),장연복 ( Jang Yeon Bog ),유형준 ( Yu Hyeong Jun ),박성우 ( Park Seo 대한내과학회 1993 대한내과학회지 Vol.44 No.5

        Backgrounds: To characterize tha IDDM in Korea, we analyzed the epidemiological and clinical features of DKA in 72 patients. Methods: Seventy-two cases thoses who met following diagnostic criteria were included in the analysis. 1) Clinical manifestation of typical DKA, 2)Blood glucise level>250 mg/dl, 3) Presence of ketonuria or keonemia, 4) Blood pH<7.34 Results: 1) The occurrence of DKA was higher in the young and infemale. 2) DKA occurred most frequently in colder season with apparent two peaks in March and December. 3) In 23.6%, DKA was the first clinical presentation of diabetes and in the remainders, diabetes wer known to be present for average of 5.4 years. 4) The most common precipitating factors of DKA was infection and omission of therapy was the next. No discernible precipitating factor was found in 26.4% of DKA cases. 5) Polyuria, polydipsia, dyspnea, nausea, vomiting and abdominal pain were frequent accompanying symptoms, and physical finding included Kussmaul breathing, tachycardia and hypotension. The mental stutus of patients were alert in 55.6% of DKA cases. 6) There was no significant difference in the body temperature, PB smear, and % of neutrophis between DKA cases with infection and those without infection. 7) On admission potassium was high in 43%, but low in 23% 6 hours after therapy. In only two-thirds of cases, fasting C-peptide level on admission was decreased in the range of classical IDDM. 8) Hypoglycemia was the most freqeunt complication during the treatment of DKA following by hypokalemia, hypernatremia, hyperkalemia, thromboembolism and ARDS. 9) Mortality of DKA was 13.9% and poor prognostic factors include old age, azotemia, associated bacterial pneumonia. Conclusions: The epidemiological and clinical feautures of DKA in Korea were similar to those in western countries, in respect to female preponderance, age, seasonal distribution, % of debut cases, precipitating fators, initial laboratory findings, complications, mortality and prognostic factors. This observation suggests that although the incidence rate of IDDM is low in Korea, there are cases that take clinical courses very similar to those of western countries.

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