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정인범 ( In Beom Jeong ),이태희 ( Tae Hee Lee ),임성민 ( Seong Min Lim ),류기현 ( Ki Hyun Ryu ),김용석 ( Yong Seok Kim ),김선문 ( Sun Moon Kim ),임의혁 ( Euyi Hyeog Im ),허규찬 ( Kyu Chan Huh ),최용우 ( Young Woo Choi ),강영우 ( Y 대한소화기학회 2011 대한소화기학회지 Vol.58 No.6
Background/Aims: The endoscopic findings and clinical relevance of portal hypertensive colopathy are not well described in Korea. We aimed to do a retrospective study of mucosal changes in the colon of patients with liver cirrhosis and to find their association with clinical characteristics. Methods: We reviewed the clinical data and endoscopic findings of 48 patients with liver cirrhosis and 48 patients, matched for age and sex, with irritable bowel disease (IBS) who underwent colonoscopy over a 5 year span. Results: Patients with liver cirrhosis were more likely to have colitis-like lesions and vascular abnormalities than IBS patients. Low platelet count (p=0.005) and severe esophageal varices (p=0.011) were associated with portal hypertensive colopathy, whereas the etiologies and severity of cirrhosis were not associated with these findings. Conclusions: Portal hypertensive colopathy can be defined with colitis-like lesions or vascular lesions. These lesions are more frequently present in patients with more severe esophageal varices and thrombocytopenia. (Korean J Gastroenterol 2011;58:332-337)