폐색전증과 동반된 동맥류 파열에 의한 뇌지주막하출혈

이형중,김동원,고용,김광명,오석전 한양대학교 의과대학 2003 한양의대 학술지 Vol.23 No.1

전이성 뇌종양의 1년간 추적 관찰연구-불량한 예후와의 연관성

이형중,김충현,김재민,백광흠,오석전,Yi, Hyeong Joong,Kim, Choong Hyun,Kim, Jae Min,Bak, Koang Hum,Oh, Suck Jun 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.9

Objective : Prognostic factors of metastatic brain tumors have been widely reported and their operative indications also have been extended gradually even to the poor grade patients. Authors intended to analyze the causative factors for the clinical outcome of metastatic brain tumors, especially with relevant to the poor prognosis by one year follow-up evaluation. Patients and Methods : The authors retrospectively studied the clinical characteristics of 46 cases(35 patients) with metastatic brain tumors among 466 cases(437 patients) which were operated on due to the brain tumor, during the period between January 1994 to June 1999. Statistical analysis was performed by using SPSS 8.0$^{(R)}$. A p-value of less than 0.05 was considered clinically significant. Result : Among the variable clinical factors in patients with metastatic brain tumors, Karnofsky Performance Scale (KPS) score of less than 70(16 patients), uncontrolled primary tumor(8 patients), and surgical resection without further adjuvant therapy(9 patients) showed statistically significant poor prognosis ; p value of 0.002, 0.032, and 0.001, respectively. Other tested variables, such as old age(greater than 65 years ; 10 patients), gender(male ; 20 patients), type of primary cancer(primary undefined ; 6 patients, lung cancer ; 15 patients), location(infratentorial ; 9 patients, sellar ; 5 patients), number of lesion(multiple ; 12 patients), and number of operation(multiple craniotomy ; 7 patients) were not related to the poor prognosis. Conclusions : The most common primary site of distant metastasis was lung. The poorer prognosis was highly correlated with various factors including low KPS score(<70), no postoperative adjuvant therapy, and uncontrolled primary tumors.

개두술 후 합병된 뇌실염에 대한 뇌실내 Vancomycin 주입 치료

이형중,김영수,고용,오성훈,김광명,오석전 대한신경외과학회 2003 Journal of Korean neurosurgical society Vol.33 No.3

Objective:To evaluate the efficiencies, shortcomings and complications of intraventricular(IVT) vancomycin instillation for controlling the postcraniotomy ventriculitis, the authors retrospectively studied clinical, radiological and microbiological profiles of such patients. Methods:We reviewed medical records and radiological findings of eleven patients with postcraniotomy ventriculitis managed between 1995 and 1999. External ventricular drainage(EVD) was performed for the purpose of retrieving cerebrospinal fluid(CSF) and instilling vancomycin. Results:The mean duration for maintaining EVD elapsed 17.8 days and IVT instillation elapsed 11.9 days. The causative pathogens were revealed in eight patients;methicillin-resistant Staphylococcus aureus(MRSA) in five, coagulase-negative Staphylococcus epidermidis(CNSE) in three. Vancomycin was instilled to patients with MRSA and CNSE. Empirical vancomycin was instilled to three patients with negative bacterial culture. Seizure was seen in one patient. Except one deceased patient, all showed clinical and laboratory improvement. Therapeutic drug monitoring(TDM) did not show any confidential relationship in three patients' status. Conclusion:Intraventricular instillation of vancomycin is an effective and safe method in treatment of the postcraniotomy ventriculitis. Complication is negligible and outcome is favorable in general. However, more refined TDM is required to attain steady CSF antibiotic concentration and prudent antibiotic selection is prerequisite to prevent formidable bacterial drug resistance. Key words:Intraventricular instillation;Postcraniotomy ventriculitis;Vancomycin;External ventricular drainage.

Threaded Fusion Cage(TFC)를 이용한 척추 전전위증 수술환자에서의 임상 및 방사선학적 소견의 분석

이형중,김남규,이승로,김영수,고용,오성훈,오석전,김광명 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.7

The indications for surgical treatment of spondylolisthesis are as follows : pain unrelieved by conservative treatment persistent neurologic signs. progression of the slip or slip greater than 50 per cent. postural deformity or walking difficulty due to tight hamstring muscles. The goal of operation for spondylolisthesis is to relieve radiculopathy and low back pain. and to prevent further progression of the slip through decompression of neural elements and fusion for pseudoarthrosis. The authors performed the posterior lumbar interbody fusion using Threaded Fusion Cage(TFC) on 23 patients with spondylolisthesis. All patients have been followed for 3 to 12 months. We then studied the clinical and radiological outcomes of these patients and verified the relationship between clinical outcomes and radiological findings. Summaries of the results are as followings. 1) Successful bone fusion was achieved in 20 out of 23 cases(87%). 2) Neurological signs were improved in 20 out of 23 cases(87%). 3) The majority of cases which demonstrated radiologic bone fusion also showed clinical improvement. Posterior lumbar interbody fusion using TFC was useful in the treatment of mild degree spondylolisthesis.

조선 大典類에 나타난 기록관리제도의 성립과 변화 양상

이형중 서울대학교 규장각한국학연구원 2021 한국문화 Vol.- No.95

Joseon was a country that pursued the rule of law. Early on, Joseon solidified its administrative system based on the establishment of the law 『經國大典』. The records and archives management system was also constituted and operated in accordance with this law. 『經國大典』 was considered as permanent law by the rulers, however, in reality it needed change because of responding to political, economic, and social variation. To overcome this legal problem, Joseon continued to supplement and compile the law like 『續大典』, 『大典通編』 and 『大典會通』. As the laws were supplemented and compiled, the records and archives management system was also reorganized ans supplemented. Joseon’s records and archives management rules which including form of official document were maintained until the late period. However the legal obligations and penalites which related records and archives were continuously enacted and supplemented in the latter. This means that records and archives were actively used in a wider public area, and then legal control of records ans archives was required in this situation in Joseon. .

경추부에 발생한 골막성 연골종의 증례 보고 : Case Report

이형중,김영수,이형석,이승로,함창곡,고용,오성훈,오석전,김남규,김광명 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.5

The authors experienced a case of cervical periosteal chondroma presenting with symptom of spinal cord compression in 26-year-old woman. The diagnosis was based on the characteristic features of computed tomographic scan and magnetic resonance imaging scan. Total surgical removal in two-staged operation was followed by full neurological recovery. column was observed and rarely reported in this literature.

대기 부하량에 제한이 있는 M/G/1 시스템의 근사법

이형중,김정기,허선 대한산업공학회 2003 대한산업공학회 춘계학술대회논문집 Vol.2003 No.5

조선 가각고의 인력구성과 존재시기에 관한 재고찰

이형중 한국기록관리학회 2020 한국기록관리학회지 Vol.20 No.3

This paper aims to elaborate on the reality of Gagakgo (架閣庫) by looking into its staff and abolition, given how Gagakgo was originally where diverse archives in Joseon were preserved. This study on Gagakgo, therefore, could be used as a basic reference to grasp the reality of the Joseon’s Records Centers and Archives. This institution was changed as a labor organization following changes in the political environment. As a result, the status and operational aspects of the institution also changed. Gagakgo was abolished once during King Sejo (世祖)’s reign and then restored during the period between King Hyojong (孝宗)’s and YoungJo (英祖)’s reign. This restored institution also performed the same role as before. This paper serves as reference to better understand the system of Gagakgo and the archival preservation system in Joseon. 가각고는 국왕의 명령인 수교(受敎)를 비롯한 국가 중요문서와 노비문서⋅행사기록 등 다양한 국가기록을 보존하는 일종의 기록보존을 위한 공간이었다. 때문에 가각고에 대한 연구는 조선의 전반적인 기록보존 공간 운영의 실상을 파악할 수 있는 기초적인 자료로 활용될 수 있으리라 여겨진다. 이를 위해 본 논문에서는 가각고의 인력구성과 혁파시점을 중심으로 가각고의 실상을 보다 상세히 규명해 보고자 하였다. 먼저 가각고는 운영을 위해 별도의 실무인력을 두었으나, 조선 초기 정치적 환경 변화에 따라 가각고의 소속과 인력 구성 또한 변경되었다. 그리고 이에 따라 가각고의 위상 및 그 운영의 양상 또한 변동되었다. 이후 세조대 들어 가각고는 혁파되었다고 알려졌으나, 조선 후기 효종~영조 연간 가각고라는 이름의 기관이 운영되었음이 확인된다. 이 가각고 또한 조선초기 가각고와 마찬가지로 실무 인력을 배치하고 기록을 보존하는 공간으로서의 역할을 수행하였다. 이는 가각고의 존재에 대한 재논의가 필요함을 보여주는 사료라고 할 수 있다. 이상의 연구를 통해 가각고 운영과 조선 기록보존의 실상에 보다 근접할 수 있을 것으로 기대한다.

백서 허혈 모형에서 D,L-6,8-Thioctic Acid가 뇌경색의 용적에 미치는 영향

이형중,이상구,이우택,김광명,김영수,고용 대한신경외과학회 2002 Journal of Korean neurosurgical society Vol.32 No.4

Objective:The authors demonstrate neuroprotective effects of antioxidant in reperfusion injury using ischemic rat model and evaluate the clinical eligibility of this agent to ischemic cerebrovascular diseases. Methods:Rat model was made according to Longa method. Thirty-six Sprague-Dawley rats were used and were equally divided into three groups;A) treated subcutaneously with D,L-6,8-Thioctic acid 30 minutes before occlusion, B) within one hour after occlusion, and C) with vehicle only. Neurologic examination was performed immediately and 24 hours after reperfusion. Twenty-four hours after reperfusion, brains were extracted and stained with 2% 2,3,5-Triphenyltetrazolim chloride in 2mm-thickness section. Then, fixed sections were digitalized and used for infarct area calculation. Results:There was no significant statistical difference in recorded hemodynamic and physiologic parameters between three groups. The neurologic status taken immediately following reperfusion were A) 2.67±0.492, B) 2.75±0.452, and C) 2.83±0.389, and were improved to A) 1.67±0.898, B) 1.92±0.900, and C) 2.08±0.793 just before sacrificing. However, there was no statistically significant difference between three groups. Mean volume of cerebral infarction was A) 9.5±1.67%, B) 10.4±1.58%, and C) 11.3±1.12% with no significant difference. Any specific correlation between the neurologic status and the mean infarction volume was not observed. Conclusion:Any single agent does not seem to reduce the infarction volume holistically, therefore, the incoming therapeutic target should be the development of versatile neuroprotective agents or the selection of preexisting synergistic compounds without compromising patients' safety. Key words:Antioxidant;Reperfusion;Rat model;D,L-6,8-Thioctic acid;Cerebral infarction;Neuroprotective agents.

朝鮮 謄錄記錄의 類型과 그 管理體系에 관한 硏究

이형중 서울대학교 규장각한국학연구원 2018 한국문화 Vol.0 No.83

This study focused on the types and the managing system of Deung-rok(謄錄). The word of ‘Deung-rok’ primarily has meant ‘copy’ or ‘retranscription’. In Joseon Dynasty, however, the word ‘Deung-rok’ had different meanings which include ‘document files’ and ‘records & archives management system’. The definition of Deung-rok needs to be clarified in the field of Korean history to avoid confusion. The Deung-rok documents were studied by separating them into five major types - ‘daily business logs’, ‘quasi law books’, ‘register or account books’, ‘administrative transactional document files’ and ‘reports & manuals’. Each type has different characteristics in structure, compiling and utilities. In addition, this study investigated the whole process of Deung-rok system, including the creation, preservation and management of Deung-rok. The Deung-rok documents were created by officials who evaluated original records and extracted and copied selected records. The Deung-rok documents were dispersed and preserved at each place based on their utilization and importance.