췌장염에서 발생한 결절성 지방괴사

박성욱 ( Sung Wook Park ),이학중 ( Han Young Wang ),왕정길 ( Hak Joong Lee ),왕한영 ( Jeong Kil Wang ) 대한피부과학회 1998 대한피부과학회지 Vol.36 No.2

Nodular fat necrosis is a rare and often overlooked sign of pancreatic disease. It is manifested as painful subcutaneous erythematous nodules, often found on the legs. We report a case of nodular fat necrosis associated with pancreatitis. The patient was a 14-year-old girl who presented with erythema nodosum-like tender subcutaneous nodules on both her lower extremities. The serum amylase and lipase levels were markedly elevated. The change of serum calcium and eosinophils were not so remarkable. Histopathological findings showed diffuse subcutaneous fat necrosis and ghost-like cells with thick shadowy walls and no nuclei. The lesions involuted gradually without any specific treatment and the underlying pancreatitis was followed up in the department of medicine. (Korean J Dermatol 1998;36(2): 346-349)

Acquired Tufted Angioma

왕정길 ( Jeong Kil Wang ),이학중 ( Hak Joong Lee ),왕한영 ( Han Young Wang ),윤혜경 ( Hye Kyoung Yoon ),박필성 ( Pill Sung Park ) 대한피부과학회 1998 대한피부과학회지 Vol.36 No.1

Acquired tufted angioma is a benign, slowly progressive angioma with a typical histological pattern that was first described by Wilson-Jones in 1976. We report a case of acquired tufted angioma in a 19 year old female who had erythematous papules and plaques on the right thigh. Histopathological findings showed multiple capillary lobules in a cannonball arrangement scattered throughout dermis, which was diagnostic of acquired tufted angioma. (Korean J Dermatol 1998;36(1): 164-167)

본태성 고혈압 및 동맥경화성 질환에서의 Prostacyclin 과 Thromboxane A₂ 혈장농도에 대한 고찰

지영구(Young Koo Jee),한형수(Hyung Soo Han),정문성(Moon Sung Jung),이봉휘(Bong Hwi Lee),김관우(Kwan Woo Kim),문언수(Un Soo Moon),한창순(Chang Soon Han),이홍순(Hong Soon Lee),이학중(Hak Joong Lee) 대한내과학회 1990 대한내과학회지 Vol.39 No.4

N/A The concentrations of the metabolites of prostacyclin and thromboxane A₂ (6-keto-PGF1α and 11-dehydro-TxB2) were measured in essential hypertension and artherosclerotic disease, and the concentrations of metabolites were compared after administration of 100 mg/日, 300 mg/日 and 900 mg/ 日of aspirin. The findings were as follows: 1) The concentrations of 6-keto-PGF1α and 11-dehydro-TxB₂ were significantly higher in the essential hypertension group and artherosclerotic disease group than in the control group (p<0.001). 2) The concentrations of 6-keto-PGF1α and 11-dehydro-TxB₂ were higher in the high cholesterol group (p<0.01, p<0.05, respectively). 3) With aspirin administration, the concenatrations of 6-keto-PGF1α and 11-dehydro-TxB₂ were significantly reduced (about 70% was reduced seven days after administration of aspirin). 4) There were no significant differences in reducing the concentrations of 6-keto-PGF1α and 11-dehydro-TxB₂ between three groups of different dosages of aspirin, 100 mg/日, 300 mg/日, and 900 mg/日 of aspirin. These findings suggest that thromboxane A₂ may contribute to the development or progression of hypertension and artherosclerotic disease. 100 mg/ 日 of aspirin may be used as effective as 300 mg/日 or 900 mg/日 of aspirin in preventing thrombotic events.

상기도 및 뇨로감염에서의 Ciprofloxacin의 효과 및 안전성 고찰

이상민,민경완,이홍순,문성수,이학중 최신의학사 1991 最新醫學 Vol.34 No.12

전경골 점액수종 2예

이학중,이상석,박성욱,왕한영 인제대학교 1997 仁濟醫學 Vol.18 No.4

전경골 점액수종은 경골 전면에 산성 점다당질이 과다 축적되는 대사 질환으로 압박시 함몰이 없는 적색 혹은 갈색의 부종성 판으로 나타나며, 대부분 그레이브스 병을 가진 환자에서 발생한다. 저자들은 임상 및 병리조직학적으로 전형적인 전경골 점액수종 2예를 경험하고 문헌 고찰과 함께 보고하는 바이다. We report two cases of pretibial myxedema associated with hyperthyroidism. Histopathologic findings of both cases shows considerable amount of mucin in upper and mid-dermis. Alcian blue staninig in pH 2.5 demonstrates extensive mucin deposition in dermis. The skin lesions of two cases has been improved by topical corticosteroid wish occlusive dressing technique.

소세포 폐암에서 동반되 피부근염 1예 : 근위 조갑추벽의 모세혈관 변화 Changes in Naifold Capillary Morphology

이상석,이학중,왕한영,박성욱,주영돈 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.10

첫 성교시 나이가 성인 질환에 연관도니 위험 성 행동에 미치는 영향

이학중,왕한영,박성욱 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.7

Background: Early age at first sexual intercourse in women is associated with an increased number of sex partners, a greater risk for sexually transmitted diseases(STD), and an increased risk for cervical neoplasia. Objective: The purpose of this study was to find risky sexual behavior for STD and to examine the correlation between the behavior and age of first sexual intercourse. Therefore we investigate whether early initiation of sexual intercourse is a risk factor for risky sexual behavior and STD. Methods: Responses to a self-administered questionniare and interview from 1132 recruit men in a Korean army recruit training center were analysed. Results: The rate of previously affected STD by first coitus were 40.6% in men who were sexually active before 15 years, 25.8% between 16 and 18 years, and 14.2% after 19 years. The men who had more sex partners tend to have higher rate of STD. The rate of STD is higher in men who experienced hallucinogens. In men who had sexual intercourse with risky sexual partners the rate of STD was higher. The experience rate of extravaginal sex had no effect on the rate of STD. Men who became sexually active before 15 years were more likely to report having 5 or more sexual partners, having coitus with risky partners, using hallucinogens, and having more prevalence of STD than other first coital age group. Conclusion: Risky sexual behavior is sexual intercourse with risky sexual partner, use of hallucinogens, more sexual partner, and early age of first sexual intercourse. In this study, our data provide evidence that early age of first intercoutse is a useful marker for risky sexual behavior and STD.

모낭성 점액증 1예

이학중,왕한영,박성욱,이상석 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.12

We report a case of follicular mucinosis in a 12-year-old girl. She had an erythematous indurated plaque with an ill-defined border on the chin. A biopsy specimen showed reticular degeneration, cystic space formation, and abundant mucin deposition in pilosebaceous follicles. She had been treated with topical corticosteroid for 3 months. The skin lesion was completely resolved.

사마귀양 혈관종 1 예

왕정길,이학중,왕한영 인제대학교 1997 仁濟醫學 Vol.18 No.4

사마귀양 혈관종은 선천성 혈관종으로 조직학적으로 혈관 각화종과 유사하나 하부 진피와 피하 지방층까지 혈관 증식이 관찰되는 것이 특징이다. 저자들은 20세 남자에서 발생한 사마귀양 혈관종 1예를 경험하고 문헌 고찰과 함께 보고하는 바이다. Verrucous hemangioma is a vascular malformation wish typical features, clinically and histologically, of a hemangioma wish a verrucous component. Most cases appear on the lower extremities, and are present birth or appear during infancy. We report a case of verrucous hemangioma developed in a 20 year old male who had dark reddish plaques on the right thigh. Histopathological findings showed hyperkeratosis, papillomatosis, and acanthosis in epidermis and proliferation and dilatation of capillaries in the papillary dermis in addition to the capillary hemangioma in the deep dermis and subcutis.

방사선치료 및 냉동치료에 호전을 보인 고전적 Kaposi 육종 1예

박성욱,이상석,이학중,왕한영 인제대학교 1998 仁濟醫學 Vol.19 No.2

Kaposi 육종은 비교적 드문 혈관 종양으로 후천성 면역 결핍증의 만연으로 인해 최근 문제시 되고 있는 질환이다. 이러한 관심으로 인해 병인에 대한 연구가 새로이 활발해진 양상을 보이고 있는데 특히 사람 헤르페스 바이러스 8형(Human Herpesvirus 8)이 주목을 받고 있다. 이에 저자들은 다발성 고전적 Kaposi 육종 1예를 관찰하고 병인론적 연구와 함께 치료적인 측면에서 환자에게 유익한 기법을 논하고자 문헌 고찰과 함께 보고하는 바이다. Kaposi's sarcoma was relatively rare vascular tumor prior to the prevalence of acquired immunodeficiency syndrome. It is divided into 4 subtypes clinically, and classic Kaposi's sarcoma shows some characteristics such as its old-male-preference and lesions predominately appearing in lower extremities. We report a case of classic Kaposi's sarcoma in a 60-year-old male patient who presented wish multiple erythematous or violaceous patches and plaques on extremities. On histopathologic examination, the lesion showed various amounts of spindle cells, vascular slips and enlarged irregular lymphatic-like spaces. He was treated with 2800cGy of initial irradiation and 560cGy of boost irradiation for lower leg lesions. For the ocher small scattered lesions, we tried cryotherapy using liquid nitrogen and cotton-tipped applicator. During radiation therapy, the lesions on the lower extremities regressed slowly and associated edema was improved. Concerning the other scattered lesions, follow up examination after 1 month of cryotherapy showed nearly complete regression. The patient presented no evidence of recurrence during a year of follow up examination.