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이준엽,김아름,정윤희,부소영 한국생물공학회 2018 Biotechnology and Bioprocess Engineering Vol.23 No.4
Long chain acyl-CoA synthetase (ACSL) is an enzyme that activates fatty acids before they are further metabolized. ACSL6 is the one of main ACSL isoforms exclusively expressed in skeletal muscle, but the consequences of the suppression of this gene in systemic glucose homeostasis has yet to be reported. Hence, we investigated the roles of ACSL6 gene in glucose tolerance and TAG distribution in physiological conditions. Eight-week-old male C57BL/6J mice were administered with control or Acsl6 siRNAs and then fed with either AIN-93 control diet or high fat diet. At seven days after the first siRNA injection, oral glucose tolerance tests and TAG quantification were performed. In vivo administration of Acsl6 siRNA decreased Acsl6 expression only in skeletal muscle under AIN-93 or a high fat diet. However Acsl6 siRNA injection to animals increased TAG accumulation in the liver without the change of Acsl6 expression. Atelocollagen mediated Acsl6 suppression enhanced whole-body glucose tolerance coinciding with decreased TAG accumulation in skeletal muscle of mice fed an AIN-93 diet. However, the improved glucose tolerance by Acsl6 reduction was ablated by high fat diet. Moreover reduced Acsl6 did not alter the phosphorylation of insulin signaling proteins in skeletal muscle. These results suggest that Acsl6 reduction in skeletal muscle enhances glucose homeostasis and dissociates the insulin responses from TAG accumulation in skeletal muscle.
만성질병 관리 프로그램 개발을 위한 탐색적 연구: 일 선원 등록자를 대상으로
이준엽,김미지,김종훈,김주현,장미란 대한질적연구학회 2023 대한질적연구학회지 Vol.8 No.1
Purpose: This study explored illness experiences and the demands for a health-related program tailored to individuals with chronic disease at one of the Korean Seon Centers. It also utilized this information as foundational data for developing a program tailored to their needs. Methods: The study utilized focus group interviews to collect data from members of one of the Korean Seon centers who have chronic disease, regarding their illness experiences and their expectations for disease management programs. The collected data was then analyzed using the qualitative content analysis method. Results: The analysis yielded five overarching themes and 14 subthemes. These themes included opposing responses to disease diagnosis, reflections on the causes of disease, efforts toward disease recovery, obstacles to disease recovery, and the need for a customized disease management program. Conclusion: The findings highlighted the challenges the participants faced in their disease recovery process. They expressed a strong desire for a comprehensive management program that incorporates in-depth information, experience sharing, and education. Such a program would empower individuals to take control of their physical and mental well-being.
음식관광객의 관여가 음식관광 참여활동과 행동의도에 미치는 영향
이준엽,권미영 관광경영학회 2009 관광경영연구 Vol.40 No.-
Integral part of the experience that it is only in recent years that it has become a subject of study in its own right. The purpose of this study is to effect of involvement of food tourists' on participation in food tourism and behavioral intention. The subject matter of this dissertation is food tourism participation in food related activities at a destination to experience its food tourists' attributes. The empirical objectives of this dissertation concerned identifying the underlying dimensions of food tourism, developing a conceptual framework that explains participation in food tourism. Survey was carried out among tourists visited in Gwangju & Jeonju region. Spsswin 12.0 statistical package were used for further analysis. The results were as follows: Firstly, Enduring involvement with food related activities is positively related to at least one dimension of food tourism. Secondly, There is a significant difference in tourists' participation in at least one dimension of tourism and their age & occupation. Thirdly, Food Tourists' on Participation had directly positive effect on satisfaction & Behavioral Intention.
이준엽 한국이론사회학회 2023 사회와 이론 Vol.45 No.-
In this study, bullying’s relevance to the classroom was identified as a parasitic relationship to the classroom. For this purpose, the school bullying interaction system was observed in relation to the classroom in factual, social, temporal dimensions through semantic analysis of narratives. At the factual dimension of meaning, I found that communication that presupposes the members of the classroom causes damage to relationships; at the social dimension of meaning, I found that survival strategies are conditioned by the structure of the peer group in relation to the classroom; and at the temporal dimension of meaning, I observed the difference between the reversibility of bullying experienced by teachers and the irreversibility of bullying experienced by students. It shows that bullying cannot be understood as a binary relationship between bully and victim, but rather as a parasitic relationship that presupposes the members of the classroom. Recognizing parasitic relation with bullying interactions in classroom opens up new ways of looking at bullying and allows us to reflect on existing efforts to address it and explore other possibilities. 본 연구는 괴롭힘이 가지는 교실과의 관련성을 교실에의 기생관계로 파악하였다. 그를 위해 학교 괴롭힘 상호작용체계를 당사자들의 서사(narrative)에 대한 의미론 분석을 통해 사실적, 사회적, 시간적, 의미 차원에서 교실과의 관계에서 관찰하였다. 사실적 의미 차원에서는 교실의 구성원들을 전제한 소통이 관계의 손상을 일으킨다는 것을, 사회적 의미 차원에서는 또래집단의 구조에 따른 생존 전략의 조건화가 교실과 관련하여 나타난다는 것을, 시간적 의미 차원에서는 교사들이 체험하는 괴롭힘의 가역성과 학생들이 체험하는 괴롭힘의 비가역성의 차이를 관찰할 수 있었다. 이들은 괴롭힘이 가해자와 피해자의 양자 관계로 파악될 수 없으며, 교실의 구성원들을 전제하는 기생 관계로 파악된다는 것을 보여준다. 괴롭힘 상호작용의 교실에의 기생 관계 파악은 괴롭힘에 대한 새로운 관찰 가능성을 열고, 기존의 해결 노력들에 대한 성찰을 통해 다른 해결 가능성을 모색할 수 있게 해준다.
이준엽,조용주,김명곤,전상규 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.1
유기발광소자는 차세대 디스플레이로서 다양하게 응용되고 있으며, 향후 응용분야가 지속적으로 확대될 것으로 예상되고 있다. 향후 유기발광소자의 시장이 확대되기 위해서는 유기발광소자의 고효율화가 필수적으로 요구되고 있으며, 유기발광소자의 고효율화를 위해서는 고효율 유기발광소재 및 소자 구조의 개발이 필요하다. 본 연구그룹에서는 고효율 유기발광소재 및 소자에 대한 다양한 개발을 진행해 왔으며, 발광 소재 및 소자 분야의 다양한 기술 및 특허를 보유하고 있다. 본 발표에서는 본 연구진에서 보유하고 있는 유기발광소자 및 소재 관련 다양한 기술을 소개하고자 한다.