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저소득가정 어머니의 양육스트레스가 우울에 미치는 영향 -자기효능감의 매개효과를 중심으로-
이주연 ( Ju Yeun Lee ),전종설 ( Jong Serl Chun ),전혜숙 ( Hye Sook Jeon ),정하은 ( Ha Eun Chung ) 한국사회복지연구회 2015 사회복지연구 Vol.46 No.2
본 연구의 목적은 저소득가정 어머니의 양육스트레스와 우울의 관계에서 자기효능감의 매개효과를 검증하는 것이었다. 본 연구는 육아정책연구소의 한국아동패널 3차년도(2010년)자료 중 23개월에서 29개월의 아동을 둔 저소득가정 어머니 174명이었다. Baron과Kenny(1986)의 매개분석 방법과 Sobel Test를 실시하여 검증한 결과, 저소득가정 어머니가 지각한 양육스트레스는 우울에 정적인 영향을 주었으며, 자기효능감은 양육스트레스와 우울과의 관계를 부분적으로 매개하는 것으로 나타났다. 이러한 연구결과는 저소득 가정 어머니를 위한 우울예방 및 개입 방안이 양육스트레스 감소와 자기효능감 증진에 초점을 두어 개발하고 실행되어야 함을 제시한다. The purpose of this study was to identify the mediating effects of self-efficacy on the relationship between parenting stress and depression among mothers in low-income families. The study sample of 174 mothers with 23-29 month-old children was taken from the 3th Korean Child Panel (2010) by Korea Institute of Child Care and Education. Using Baron & Kenny(1986)``s mediating analysis and Sobel test, the study found that parenting stress has positive relationship with depression among mothers in low-income families, while self-efficacy plays a partially mediating role between the two variables. The study results suggest that the prevention and intervention programs for depression among mothers in low-come families must pay attention to decreasing parenting stress and improving self-efficacy.
알레르기 ; 자발적 약물유해반응 데이터베이스를 이용한 항암제 유해사례 현황 분석
이주연 ( Ju Yeun Lee ),정재우 ( Jae Woo Jung ),강혜련 ( Hye Ryun Kang ),이세훈 ( Se Hoon Lee ),김향숙 ( Hyang Sook Kim ),조상헌 ( Sang Heon Cho ) 대한내과학회 2013 대한내과학회지 Vol.85 No.4
본 연구는 국내 자발적 보고된 항암제 유해사례에 대한 서술적 분석이었으며 가장 유해사례 보고가 많은 계열의 항암제는 pyrimidine 유사체였으며 항암제와 관련되어 가장 흔히 보고된 부작용 양상은 위장관계 부작용과 피부, 부속기계 부작용이었다. 또한 본 연구에서 확인된 미반영 유해사례에 대해서는 그 인과 관계를 평가하기 위해서 향후 지속적인 모니터링과 연구가 필요할 것으로 사료된다. Background/Aims: To describe the toxicity profile of anti-neoplastic agents from real clinical settings, we analyzed spontaneously reported adverse events (AEs) using data from the adverse drug reaction (ADR) reporting system of the Korean Food and Drug Administration (KFDA). Methods: Data were extracted from the nationwide spontaneous ADR reporting system of KFDA from July 2009 to December 2010. We extracted and analyzed data related to chemotherapy and identified unlabeled ADR that were not described in the package insert of the products. Results: In total, 5,867 cases of antineoplastic agent-related AE reports were identified after excluding cases for duplication and cases assessed as ‘unlikely’ and ‘unclassifiable’, based on expert opinion. Of the patients with AEs, 52.4% were males and the median age was 56 years. In total, 460 AEs (7.8%) from 267 patients were reported as ‘serious’ AEs. The most common causative anti-cancer drug class was pyrimidine analogs (31.5%), followed by platinum compounds (19.9%), protein kinase inhibitors (10.8%), and taxanes (8.8%). The most common clinical manifestation of AEs was gastrointestinal toxicities (25.5%), followed by skin disorders (25.3%), and generalized reactions (14.3%). In total, 168 cases (2.9%) of unlabeled AEs were identified. Among these, 10 were reported as serious AEs. Conclusions: The most common causative class of antineoplastic agents was that of pyrimidine analogs. Gastrointestinal and dermatological toxicities were the most common clinical chemotherapy-related adverse events. Further investigation and monitoring to evaluate causality associated with unlabeled AEs identified in this analysis are needed. (Korean J Med 2013;85:385-395)
청소년의 인터넷 중독이 학업적응에 미치는 영향 -정서조절의 매개효과를 중심으로-
이주연 ( Ju Yeun Lee ),전종설 ( Jong Serl Chun ) 한국청소년복지학회 2015 청소년복지연구 Vol.17 No.1
본 연구의 목적은 청소년의 인터넷 중독과 학업적응의 관계에서 정서조절의 매개효과를 검증하는 것이었다. 한국정보문화진흥원의 2013년 인터넷 중독 진단척도 타당도 고도화 조사 자료를 2차 분석하였는데, 수도권 소재 중학교, pc방, 병원에서 표집한 총 408명의 중학생을 대상으로 하였다. 사용된 척도는 인터넷 중독, 정서조절, 학업적응 등이었고 청소년의 성별, 연령, 학업성적, 경제수준 등이 통제변수로 사용되었다. 상관분석, 회귀분석, Baron과 Kenny(1986)의 매개분석과 Sobel Test를 실시한 결과, 청소년이 지각한 인터넷 중독은 학업적응에 부정적인 영향을 주었다. 또한 정서조절은 인터넷 중독과 학업적응과의 관계를 부분적으로 매개하는 것으로 나타났다. 이러한 연구결과는 인터넷 중독과 학업적응 사이의 관계에서 정서조절이 매개효과가 있다는 것을 검증하였다는데 의의가 있다. 따라서 본 연구결과는 청소년의 학업적응을 위해 학교 및 지역사회에서 인터넷 중독 예방 및 개입에 대한 인식을 증진시키고 청소년의 인터넷 중독으로 인한 학업 부적응 해소를 위한 정서조절 프로그램 개발의 근거자료로 활용될 수 있을 것이다. The purpose of this study was to identify the mediating effect of emotion regulation in relations between adolescent internet addiction and academic adjustment. The secondary data analysis was conducted using a validation study of a diagnostic tool for internet addiction by National Information Society Agency. Using the purposive sampling method, a total of 408 adolescents in metropolitan area were recruited from middle schools, PC rooms, and hospital. The internet addiction, emotion regulation, academic adjustment, control variables such as gender, academic records. and economic status were measured. The analysis of data used correlation analysis, regression analysis, Baron & Kenny(1986)``s mediating analysis, and Sobel test. The study results were as follows. Adolescent``s internet addiction had a negative influence on the academic adjustment. Also, the emotional regulation had a partial mediating effect between adolescents`` internet addiction and academic adjustment. Based on these findings, this study suggests that preventive education and counseling for internet addiction in school and community need to be focused. Also, interventions for improving emotional regulation need to be developed and implemented.
이수현(Suhyun Lee),아영미(Young-Mi Ah),허규남(Kyu Nam Heo),이아영(Ah Young Lee),민상일(Sang il Min),김아정(A Jeong Kim),김성환(Sung Hwan Kim),조윤희(Yun Hee Jo),조윤숙(Yoon-Sook Cho),한지민(Ji Min Han),이주연(Ju-Yeun Lee) 대한약학회 2022 약학회지 Vol.66 No.5
Despite the fact that a considerable number of preventable adverse events are managed in primary care settings, medication-related risks have been evaluated mainly through hospital admissions. While interest in high-alert medication management in the community and primary care settings is increasing internationally, Korea does not have accreditation for the same and lacks established standards for high-alert medications. Therefore, this study aimed to develop a nationallevel list of high-alert medications for community and primary care. The candidates for the high-alert medication list included medications recommended by Institute for Safe Medication Practices and those suggested by each guideline of the World Health Organization, Japan and Korea. We analyzed the adverse events related to medication errors reported by the patients' safety reporting system. Seven experts working in the community and primary care settings evaluated the adequacy and priority of the candidate medications. The final list included 20 high-alert medications, including nine essential and eleven optional medications. The national-level list of high-alert medications which we developed may be useful in formulating accreditation guidelines or treatment standards for community and primary care patients.
중등도 이상의 위험 수술을 받은 환자에서 수술 전후 항혈전제 약물 사용 평가
이현아,조윤희,조윤숙,한현주,이주연,정근화,이상건,Lee, Hyeon-Ah,Jo, Yun Hee,Cho, Yoonsook,Hahn, Hyeon Joo,Lee, Ju-Yeun,Jung, Keun-Hwa,Lee, Sang Kun 한국임상약학회 2017 한국임상약학회지 Vol.27 No.1
Objective: The perioperative management of antithrombotic therapy is often challenging and it requires a fine balance between the risk of hemorrhage and thrombosis. We aimed to evaluate the antithrombotic management for moderate to high risk patients in real world setting. Methods: Among the patients who were consulted to the neurologist for the evaluation of perioperative risk from 2010 to 2012, patients undergoing moderate to high risk surgery and taking antithrombotics within 30 days were identified. We analyzed the timing of discontinuation and reinitiation of antithrombotic drugs before or after surgery as well as the status of bridging therapy. In addition, the conformity with the guideline suggested by American College of Chest Physicians was assessed. The rate of thromboembolic event and major hemorrhage were also investigated. Results: A total of 329 patients were included. The concordance rate of warfarin stop and restart time with guideline was 23.4% and 10.3%, respectively. Continuing aspirin in patients undergoing coronary artery bypass surgery or non-cardiac surgery in patients with high risk for cardiovascular events were 59.2% and 2.6%, respectively. Bridging therapy was adopted in 92.9% and 81.2% in patients who had received anticoagulant before surgery and who were at high and low risk thromboembolism, respectively. In entire cohorts, 30-day incidence of major bleeding and thromboembolic event were 31.9% and 3.0%. Co-morbid renal disease were shown as independent predictor for major bleeding (adjusted OR 2.65. 95% CI 1.33-5.28). Conclusion: The concordance rate with guideline regarding perioperative antithrombotic use was low and bridging therapy was prevalent in patients undergoing moderate to high risk surgery.