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      • 난관복원수술에 Loupe사용의 유용성에 관한 임상적 연구

        이임순 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.2

        The purpose of the study is to define the merit of Looupe by comparing the results of tubal reanastomosis using Loupe and operating microscope. Between January 1990 to December 1993, tubal reanastomosis was performed in 118 women using Loupe in the Department of Obstetrics and Gynecology, Soonchunhyang University Hospital. 106 cases were able to follow up more than 6 months. The results were as follows: 1. The characteristics of patients at the time of reversal were as follows ; the mean age was 32.7(26-43)years, mean number of living children was 1.4(0-3) and average interval between sterilization and reversal was 64.1(18-144)months. 2. The intrauterine pregnancy rate was 77.4% in 106 cases of tubal reversal which were able to follow up more than 6 months. 3. Reasons for tubal reversal was the change in attitude(44.1%), change in marrital status(39.8%), and death of child(16.1%). 4. The average interval tubal length was 6.7cm. The length was 7.3 cm in pregnant group and 5.9 cm in nonpregnant group. 6. Refering to the sterilization types, the most common sterilization type was cautery method(53.4%). The pregnancy rate was 82.9% in Falope ring, 80.9% in Pomeroy's, and 72.7% in cautery method. 7. Refering to the tubal length, the pregnancy rate was 50.0% in 3-5cm, 78.9% in 5-7 cm, and 92.1% in 7 cm or more. 8. The pregnancy rate within the first year after reversal was 72.7%(77/82), but no case after more than two years after tubal reanstomosis. 9. The mean operation time of tubal reanstomosis using Loupe was Ihr 40min.(1-2hrs; 83%) 10. The outcome of the 84 pregnancies after reversal was as follows: 69 cases(82.1%) of term delivery, 3 cases(3.6%) of spontaneous abortion, 2 cases(2.4%) of ectopic pregnancy, 10 cases(11.9%) of pregnancy in progress. In conclusion, there was no difference of pregnancy sucess rate between optical loupe and operating microscope. Thus, loupe will be a useful tool for tubal reanstomosis in the cost, operating tubal, and operating time.

      • KCI등재
      • KCI등재후보

        섭식절제척도의 타당도 연구: 섭식절제 및 역규제적 섭식 척도들 간의 비교

        이임순 한국건강심리학회 2002 한국심리학회지 건강 Vol.7 No.1

        The present study explored the reliability and validity of the Restraint Scale, Korean version. Nondieter group consists of 228 female college students and dieter group consists of 168 female students, also. Factor analysis of the Restraint Scale for both groups produced two replicated factors: Concern for Dieting and Weight Fluctuation. This study was conducted to determine the correlations and the factors of the Restraint Scale, the Three Factor Eating Questionnaire, and the Dutch Eating Behavior Questionnaire. A factor analysis showed three factors. The first factor was formed by counter-regulation (EDI-Bulimia, TFEQ-Disinhibition, TFEQ-Hunger, DEBQ-External Eating, DEBQ-Emotional Eating). The second factor was formed by dietary restraint (TFEQ-Cognitive Restraint, DEBQ-Restrained Eating, RS-Concern for Dieting, EDI-Drive for Thinness). The third factor was formed by weight fluctuation (BMI, EDI-Body Dissatisfaction, RS-Weight Fluctuation). Although these three scales may be significantly correlated, they may assess different constructs. 본 연구에서는 섭식절제척도(RS)의 타당도를 알아보기 위하여, 체중조절을 실행하고 있지 않은 여대생 228명과 다이어트를 실행하고 있는 여대생 168명에 대하여 섭식절제척도의 요인분석과 문항분석을 실시하였다. 두 집단 모두에서 다이어트에 대한 관심과 체중변동 요인이 나타났다. 섭식절제와 역규제적 섭식척도들 간의 상호연관성을 알아보기 위하여, 체중조절을 실행하고 있지 않은 여대생 228명의 섭식절제척도(RS), 식이행동 질문지(DEBQ) 및 삼요인 섭식 질문지(TFEQ), 섭식장애검사(EDI-2)의 하위척도들, 신체질량지수 간의 상관을 알아보고, 하위척도별로 요인분석을 실시하였다. 요인분석 결과, 요인부하량이 1 이상인 세 요인이 전체 변량의 56%를 설명하는 것으로 나타났다. 요인 1은 주로 역규제적 섭식 및 정서적, 외부적 섭식으로, 요인 2는 섭식절제와 관련된 척도로, 요인 3은 체중 변동이나 신체 불만족, BMI와 같이 체형과 관련된 척도로 구성되어 있다. 섭식절제와 역규제적 섭식 및 체중변동 요인에 대해 각 척도들이 공동으로 측정하는 부분과 독특하게 측정하는 부분을 구분함으로써 각 척도의 특성을 구체화하였다.

      • SCIESCOPUSKCI등재

        자궁경부암의 발암과저에서 아포토시스의 역할

        이임순,남계현,이권해,최규연,이순곤 대한부인종양 콜포스코피학회 1997 Journal of Gynecologic Oncology Vol.8 No.3

        A considerable body of evidence has been accumulated suggesting that invasive squamous cell carcinoma develops from cervical intraepithelial neoplasia(CIN). Most women with invasive cancer of the cervix are from lower socioeconomic groups, have begun heterosexual activity early in life, marry early, are multiparous, and have many sexual partners. Although the epidemiology of the cervical cancer is known well, the pathogenesis of the cervical cancer from CIN is subtle yet. Apoptosis, including the programmed cell death, is important event in normal cell turnover and maintenance of adult tissues. Apoptosis exerts a homeostatic function in relation to tissues dynamics, as the steady state of continuously renewing tissues achieved by a balance between cell replication and cell death. The specific labelling of nick ends of fragmented DNA was used to see the apoptotic cells from normal epithelium of the cervix to invasive cervical cancer. The apoptotic cells were found normally in the parabasal layer of the epithelium. As the grade of CIN increase, the apoptotic cell were found in superficial layer of the cervix and number of the apoptotic cell were increased. In the cervical cancer, the apoptotic cell were found in the cancerous tissues more than in the normal epithelium. This result suggest that the cell proliferation is more important than the inhibition of the apoptosis in the carcinogenesis of the cervical cancer.

      • KCI등재

        정상 임신부에서 혈청내 Interleukin-2와 Tumor Necrosis Factor-α 값의 변화

        이임순,이순곤,이해혁,김동희,이슬기,양회경,최경훈 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.7

        목적: 태아는 면역학적으로 반동종이식(semiallograft)이고, 일부의 반복유산이 숙주와 이식편 사 이의 반응때문이라면, 숙주와 이식편 관계에 있어서 중요한 역할을 한다고 알려져 있는 interleukin-2[IL-2]와 tumor necrosis factor-α(TNF-α)의 측정이 흥미롭다고 할 수 있다. 본 연구에서는 임신중 일어나는 면역학적 변화에 대한 예비연구로 임신부의 혈청내의 IL-2와 TNF-α 값을 측정하였다. 연구방법: 혈청 TNF-α와 IL-2는 효소 결합 면역흡착검사[ELISA kit: R&D system, Mineapolis, MN]를 사용하여 측정하였고, 대상은 50명의 합병증 없는 임신부, 30명의 건강한 비임신부, 적어도 2번 이상의 유산경력이 있는 5명의 임신부를 대상으로 하였으며, 이 5명의 임신부는 임신 6-14주였고, 채혈당시 질출혈과 절박유산 증상으로 세번째 결국 유산 하였다. 통계적 처리는 student t test를 사용하였다. 결과: 혈청 IL-2값은 비임신부와 정상임신부에서 각각 11.0 22.5pg/mL 와 66.2 47.5pg/mL로 검출되어 임신부에서 증가하였으며, 임신 초기에 증가하여 임신 기간중 일정하였다. 혈청 TNF-α 값은 비임신부와 정상임신부에서 각각 11.6 28.1pg/mL와 11.4 21.8pg/mL로 검출되어 차이가 없었다. 숫자는 적으나 원인불명의 반복유산환자에서 혈청 IL-2값은 어떤 규칙을 찾을 수가 없어 의미가 없었으나, 혈청 TNF-α값은 29-34pg/mL로 정상임신부에 비하여 높게 나타나는 경향을 보였다. 결론: 비임신부와 정상임신부의 IL-2값에 차이가 있으며, 임신부에서 IL-2값이 증가하였다. 비임신부와 정상임신부의 TNF-α값은 차이가 없었다. 수는 적으나 원인불명의 반복유산 환자에서 정상임신부에 비하여 TNF-α값이 증가되는 경향을 보였다. Objective: Because the fetus exists immunologically as a semiallograft, pregnancy loss may be a manifestation of host versus graft rejection in some cases. So we undertook a preliminary study to determine IL-2 and TNF-α levels in serum during normal pregnancy. Methods: Samples were taken for serum TNF-α and IL-2 enzyme linked immunosolvent assays (ELISA: R&D systems, Minneapolis, MN) from 50 pregnant women without any complications, 30 healthy non pregnant women and 5 women with at least two previous abortions between 6-14 weeks. 5 women had symptoms of an threatened abortions as evidenced by a vaginal bleeding and ultimately had a third abortion. Statistical analysis was used student t test. Results: Serum IL-2 levels were determined respectively 11.0 22.5pg/mL and 66.2 47.5pg/mL in control and normal pregnant women. The peak IL-2 level was reached as early as the first month and was stable during pregnancy. Serum TNF-α levels were determined respectively 11.6 28.1pg/mL and 11.4 21.8pg/mL in control and normal pregnant women. Serum TNF-α levels in women with unexplained recurrent abortion were 29-34pg/mL. Conclusions: In normal pregnant women we found an increase in serum levels of IL-2 compared to the non-pregnant women. As regards serum levels of TNF-α, no differences could be observed between normal pregnant and non-pregnant women. In women with URA an increase in serum levels of TNF-α were found compared to the normal pregnant women.

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