향정신성약물(向精神性藥物)이 뇌(腦) amine 함량(含量) 변동(變動)에 미치는 영향(影響)(제 1 보고)(第 1 報告)

이세규,김혜성,Lee, Se-Kyu,Kim, Hei-Sung 대한약리학회 1970 대한약리학잡지 Vol.6 No.1

The present study is concerned with the demonstration of the relationship between the behavior and the brain concentration of noradrenaline resulted from pretreatment of amphetamine in isolated or aggregated rats. The experimental subjects were rats weighing from 120g to 200g housed 1, 2, and 6 in a cage. Analeptic activity of amphetamine was measured by determining the sleeping time induced by pentobarbital sod. The noradrenaline content in brain was determined with Aminco-Bowmann's spectro-photofluorometer by Lee's modification of Shore and Olin method. Results: 1) The analeptic activity of amphetamine on the sleeping time induced by pentobarbital sod. was more increased in the grouped rats than in isolated animal. 2) In being isolated and grouped rats, the sleeping time induced pentobarital sod, was markedly prolonged by pretreatment of amphetamine. 3) Means of housing rats, e.g., isolation or aggregation did not seem to affect the brain noradrenaline depleting action. 4) Repeated daily parenteral administration of amphetamine sulfate for a period 1 to 3 weeks resulted in decrement of brain noradrenaline concentration in being isolated and grouped rats. 5) The prolongation of sleeping time of the isolated or aggregated rats, when pretreated with amphetamine, compared with that of stock rats, seems to be attributable rather to the means of housing than the variation of the noradrenaline caused by amphetamine.

"중국민족의학사(中國民族醫學史)에 관(關)한 연구(硏究)"

이세규,신순식,Lee, Se-Gyu,Sin, Sun-Sik 대한한방내과학회 1994 大韓韓方內科學會誌 Vol.15 No.1

표면결함이 있는 복합적층 시편의 강도

이세규,홍창선 ( Sei Kyu Lee,Chang Sun Hong ) 한국복합재료학회 1989 Composites research Vol.2 No.2

오가피(五加皮) Ethanol Extract의 실험적(實驗的) 신성고혈압(腎性高血壓)에 미치는 영향(影響)

이세규,고석태,임동윤,Lee, Sae-Kyu,Ko, Suk-Tai,Lim, Dong-Yoon 한국약제학회 1978 Journal of Pharmaceutical Investigation Vol.8 No.3

This study was carried out for the purpose of observing the effect of Korean Acanthopanax Radicis Cortex on renal hypertension and to clarify the mechanism of this effect, making use of its ethanol extract. Adult male or female rats, weighing 180-250g, were divided into 3 groups; the first for normotensive control, the second for hypertensive control and the third for hypertensive Acantopanax-treatment. Rats in the normotensive and hypertensive control group were administered 0.9% saline subcutaneously only, whereas those in the Acanthopanax-treated hypertensive group were administered 50mg/kg Acanthopanax ethanol extract subcutanously once a day. Changes of original blood pressure, and responses of blood pressure to various 4gents(norepinephrine, angiotensin, acetylcholine, serotonin and histamine) were recorded for each group on the initial, 18th, 32nd and 46th days of the experiment. The results obtained in this experiment are as follows: 1) The initial blood pressure was $102.6{\pm}7.6mmHg$ on the average. The blood pressures of the normotensive control group were not observed to alter significantly at any period in the course of the experiment. 2) The mean blood pressures in the hypertensive control group were recorded at $120.3{\pm}10.4mmHg$ on the 18th day, at $134.5{\pm}9.2$ on the 32nd day and at $138.8{\pm}8.3$ on the 46th day, thus revealing significant elevation in comparison with the corresponding normotensive control group blood pressures. On the other hand, the mean blood pressures in Acanthopanax-treated hypertensive group on the 18th, 32nd and 46th days were $118.3{\pm}9.7,\;129.9{\pm}8.3\;and\;120.2{\pm}8.3mmHg$ respectively. The blood pressures of the hypertensive-Acanthopanax group recorded. on the 46th day revealed a significant difference as compared with those of the corresponding hypertensive control group. 3) On the 46th day of this experiment, the responses of blood pressure to acetylcholine in the hypertensive-Acanthopanax group were suppressed significantly as compared with those of the hypertensive control group, and in the latter group, angiotensin was decreased markedly as compared with the corresponding normotensive control group. In contrast, pressor action of norepinephrine and depressor action of serotonin and histamine did not differ significantly among the three groups. These results suggest that Acanthopanax ethanol extract suppresses the induction of renal hypertension by means of a cholinergic action such as that caused by acetylcholine.

주민효능감이 지역재생 및 활성화를 위한 지연산업 개발태도에 미치는 영향에 관한 연구

이세규 ( Sekyu Lee ) 성균관대학교 국정관리대학원 2013 국정관리연구 Vol.8 No.1

본 연구의 목적은 주민효능감이 침체 또는 쇠퇴를 겪고 있는 지역의 지연산업 개발태도에 미치는 영향에 관한 인과성을 검증하여 성공적인 산업화를 위한 정책적 제언을 하는데 있다. 이 같은 연구목적을 달성하기 위해, 본 연구에서는 주민효능감, 향토자원 산업화 인지도, 지연산업에 대한 선행연구를 고찰하여 연구가설을 설정하고, 이를 검증하기 위해 구조모형방정식(SEM)을 활용하였다. 본 연구의 검증결과는 다음과 같다. 우선, 주민효능감은 지연산업 개발태도에 정(+)의 인과관계에 있었다. 주민효능감과 지연산업 개발태도 간의 인과성은 향토자원 산업화 인지도를 매개변수로 할 경우, 정(+)의 인과성이 더욱 커지는 것으로 검증되었다. 이 같은 연구결과로 인해 다음과 같은 정책제언을 한다. 침체 또는 쇠퇴된 지역의 성공적인 지연산업을 위해서는 대상지를 선정하는 단계에서 본 연구에서 제시한 효능감(efficacy)의 측정지표(index)를 선정하여 평가에 반영하며, 정책의 추진과정 중에도 주민효능감을 높일 수 있는 프로그램을 개발하여 운용해야 한다. The purpose of this study is to examine the causal relationships among the perception of the collective efficacy, the local industry, and the attitude of local development and to find policy implications on successful local resources and place marketing`s strategies. To achieve this purpose, this study reviews the existing literatures about the collective efficacy, the local industry`s preception and the attitude of local development, and then formulates some study hypotheses and finally verifies them using a structural equation model. The main results of this study are as follows. 1) The collective efficacy affects the local industry perception and the local development positively. The policy implications of theses finding is as follow. In order to make successfully businesses using local resources which are included by collective efficacy. The local government should estimate residents and participatory agents` collective efficacy while they make the local resource`s business proposal. And The central government should reflect collective efficacy when they make a choice the order of priority.

뉴타운 입주자의 거주후 만족도 및 지역 충성도에 미치는 영향요인분석

이세규(Lee Se Kyu),안형순(An Hyung-Soon) 한국도시행정학회 2009 도시 행정 학보 Vol.22 No.3

The purpose of this study is to examine the causal relationships among the satisfaction of New Town Residents and the local loyalty, and to find policy implications on successful New Town strategies. To achieve this purpose, this study reviews the existing literatures about Customer Satisfaction Index(CSI) and then formulates 9 study hypotheses, and finally verifies them using a structural equation model. This study uses a field survey data about residents who moved into a ‘Eun Pyeong New Town’and the final sample size is 336. The main results of this study are as follows. 1) New Town Image affects New Town Expectation and Perceived Quality. 2) New Town Expectation also affects Perceived Quality but doesn’t have any statistically significant effects on Perceived Value and New Town Satisfaction. Perceived Quality affects Perceived Value and New Town Satisfaction. And Perceived Value affects New Town Satisfaction. 3) New Town Satisfaction has a very strong positive effect on Loyalty. The policy implications of these findings are as follows. 1)In order to maximize residents’satisfaction, local government officials and the authorities concerned should make the best efforts to enhance perceived quality of New Town. 2)To make New Town loyalty effects come true, it is very important to retain the residents showing various methods which are operating and managing about the New Town.

도시 노인복지시설의 만족도와 충성도가 사회적 관계, 신체건강에 미치는 영향연구: 광주광역시 빛고을노인건강타운을 사례로

이세규 ( Segyu Lee ) 성균관대학교 국정관리대학원 2015 국정관리연구 Vol.10 No.2

본 연구는 광주광역시 노인복지시설의 만족도와 충성도가 사회적 관계와 신체건강에 미치는 영향을 검증하고자 한다. 이를 위해, 고객만족지수(CSI)에 관한 이론과 사회적 관계가 건강에 미치는 인과성에 관한 선행연구를 고찰하여 연구모형을 설정하였다. 본 연구는 노인건강타운을 이용하고 있는 고령자 361명을 대상으로 설문조사를 실시하여 검증하였다. 분석결과는 첫째, 시설의 만족도가 이용자의 충성도에 정(+)의 영향을 미쳤다. 이때, 만족도가 사회적 관계를 매개변수로 한 연구가설에서 충성도에 강한 정(+)의 영향을 주고 있었다. 둘째, 사회적 관계는 신체건강에 정(+)의 영향을 미치고 있었다. 그러데, 사회적 관계는 노인복지시설의 충성도를 매개변수로 한 연구가설에서 신체건강에 정(+)의 영향력이 더 커지는 것으로 나타났다. 따라서 노인복지시설의 성공적인 운영을 위해서는 노인들의 만족도와 충성도를 높일 수 있는 시설관리와 서비스뿐만 아니라, 사회적 관계와 신체건강을 높일 수 있는 다양한 지원체계와 프로그램을 운영해야 한다. 또한, 생활권별로 마을단위의 적합한 고령친화형 도시계획시설인 노인복지시설의 설립과 운영에 필요한 정책과 지침을 마련해야 한다. In this study intends to verify the causality among the local elderly welfare facilities of satisfaction, loyalty, social relationships and physical health. To this end, we review of previous research on the theory of the social relationships and physical health and on the Customer Satisfaction Index(CSI). In order to test, we verified Bitgoeul Senior Health Town for 361 people aged 60 and older by conducting a survey. Major results of this research are as follows. First, satisfaction of the elderly welfare facilities were having a positive effect on customer loyalty. At this time, the influence of the satisfaction was more positive for loyalty in the research hypothesis social relationships as a parameter. Second, social relationship was having a positive effect on physical health. However, the influence of social relationships is more positive physical health in the research hypothesis loyalty of the facility as a parameter showed. Therefore, elderly welfare facilities management to increase the satisfaction and loyalty of the elderly to use the facilities for successful settlement of facilities and services, as well as a variety of support systems and programs to improve the social relationships and physical health should be operating. In addition, by providing a policy and guidelines for elderly-friendly urban planning facilities in neighborhood should be supplied.

도시의 창조성과 고용성장 간의 영향관계

이세규(Lee, Se-Kyu) 한국도시행정학회 2011 도시 행정 학보 Vol.24 No.4

There have been some studies on the economic ripple effect of the creative city, creative class, and creative index by the metropolitan city’s cross-sectional data. Nevertheless, it has rarely been studied for local small and median sized cities focusing on the direct causality of between the creative index and the jobs’ change by the time series data. This paper develops the question which creative index could be effective to be increasing continuously the job growth long time. To be tested this question, the theory of the creative city was studied. And this study reviews the existing literatures about the Latent Growth Curve Model which is an analytic model, then sets up the analysis framework, formulate hypotheses and, finally verifies them. These local cities are classified by the employment’s growth and creative index increasing group and excluded the declining city group, because these cities’ total jobs have been increased for last ten years continuously. Meaningful results are yielded by using the LGM. Firstly, it has only a statistical significance the casuality relationship between the tolerance increasing and the total job growth, and also the creative technology has affected total job’ growth. However, it has no the statistical significance the casuality relationship between the creative class and total job’s increasing.

근린무질서와 구도심 노인거주환경 만족도의 영향연구

이세규(Lee, Se-Kyu) SH도시연구원 2017 주택도시연구 Vol.7 No.1

The purpose of this study is to examine the influencing relationships among the neighborhood disorder, place attachment, social capital and residential environment satisfaction of the elderly of old CBD in Sun-cheon city, and go find policy implications on successful the aging-friendly urban regeneration’ strategies. To accomplish this purpose, such as this study re-examines the advance literatures about neighborhood disorder, place attachment, social capital, and elderly residential satisfaction. And then develops this study hypotheses, and finally examines them using the SEM. The main results are as follows. Firstly, the neighborhood disorder affects the place attachment, the social capital and the elderly residential environment satisfaction negatively. However, the elderly’s the place attachment is very strong affecting factor to the social capital and the elderly residential environment satisfaction. Finally, the elderly’s social capital has a positive effect the elderly residential environment satisfaction positively. Here is the policy implications. The old CBD’s regeneration should be looking a new approach for aged society. In order words, the place attachment and the social capital should be continuously maintained in old CBD’s community. Above all, the government should prepare the aging-friendly urban regeneration and the aging in place’s policy and program for the elderly residents and community.

유비쿼터스 도시개발에 대한 만족도와 사회적 유대관계

이세규(Lee, Se-Kyu),이재수(Lee, Jae-Su) 한국도시행정학회 2011 도시 행정 학보 Vol.24 No.3

The intends of this study is to examine the causal relationships among the satisfaction and social relationship of the u-City residents and to find policy implications on successful u-City development. To achieve the purpose, this study reviews the existing literatures about u-City, Place Attachment, Creative City, Customer Satisfaction Index and Social Capital theories. This study uses a field survey data about ‘Eun-pyeong’ residents who live this area and the sample size is 338. The main results of this study are as follows. 1) u-City Residents Satisfaction has a negative effect on Social Relationship. 2) However, Residents Satisfaction has a positive effect on Social Relationship by the u-City Loyalty and Place Attachment. The policy implications of theses findings are as follow. To make successful development of the u-City, local government should prepare to set the monitoring system for perceived u-City’s loyalty and place attachment of residents. In order words, the u-City development should be focused residents who are recognized the u-city’loyalty and the place attachment strongly.