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감마선조사 생쥐의 폐 및 심장조직중의 Superoxide Dimutase 활성도에 대한 연구
이상협,전현우,김우제,양종대,차종희 朝鮮大學校 附設 醫學硏究所 1986 The Medical Journal of Chosun University Vol.11 No.1
The change of cytosolic superoxide dismutase (E.C.1.15.1.1. ) activities in the lung and heart of mice irradiated with a single dose of gamma irradiation 400 rads for the whole body was examined. The specific activities of superoxide dismutase in cytosol fraction of lung and heart were decreased to lowest levels on 7 day after irradiation and the activities of superoxide dismutase per gram of the organ tissues were decreased to lowest level on 21 day after irradiation. Also the total activities of superoxide dismutase per lung and heart were decreased to lowest level on 7 day after irradiation, It is concluded that the superoxide dismutase activity in cytosol of heart is more decreased than the activity in cytosol of lung after irradiation.