http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
이명석,조정연,김승협 대한초음파의학회 2010 ULTRASONOGRAPHY Vol.29 No.2
Purpose: To retrospectively evaluate the diagnostic value of ultrasonographic differentiation of small angiomyolipomas (AMLs) from renal cell carcinomas (RCCs) by measuring relative echogenicity (RE) on PACS. Materials and Methods: Thirty-six cases of < 3 cm, pathologically-proven RCCs and 42 cases of size-matched AMLs were enrolled. We measured the grayscale representing echogenicity of the mass, the renal cortex, and the sinus fat on PACS using a ROI cursor. The RE of the tumor was calculated by setting the grayscale of the renal cortex and sinus fat as 0% and 100%, respectively. We compared REs of AMLs and RCCs, including subgroups of each tumor. ROC analyses between RCCs and AMLs or non-fatty AMLs were performed for obtaining diagnostic performance (Az value) of RE measurement and for extracting sensitivities of RE with fixed specificities of 90%and 95%. Results: The RE of AMLs was higher than RCCs (p < 0.05). The RE of non-fatty AMLs was significantly lower than fatty AMLs, and higher than any subgroups of RCCs (p < 0.05). RE measurement provided good diagnostic performance (Az ≥0.840, p < 0.05) with competitive sensitivity/specificity for differentiating AMLs from RCCs regardless of AML subgroups. Conclusions: RE measurement on PACS can be helpful in the differential diagnosis of small AMLs and RCCs with the intrinsic merits of ultrasonography.
Cross-flow filtration에 의한 Bifidobacterium longum의 고농도 배양
이명석,박연희,Lee, Myong-Suk,Park, Yun-Hee 한국응용생명화학회 1997 Applied Biological Chemistry (Appl Biol Chem) Vol.43 No.1
Bifidobacterium longum을 고농도 배양하기 위하여 최적 생육 조건을 조사하고 cross-flow filtration으로 생육 저해 대사산물인 lactic acid와 acetic acid를 제거하면서 균체 순환 배양을 사용하였다. 회분 배양에서는 탄소원으로 glucose를 50 g/l 농도로 사용하고 초기 pH 6.5인 경우 생육이 가장 높았다. B. longum을 cross-flow filtration으로 12시간 배양한 결과, 희석속도 $0.31h^{-1}$에서 최대 균체농도에 도달하여 16.4g/l의 건조균체량을 얻었으며 이로써 회분 배양시 보다 약 4배 높은 균체를 생산하였다. The conditions for production of high cell density of Bifidobacterium longum were investigated and the cross-flow filtration system was used to remove the inhibitory metabolites, lactic acid and acetic acid. The maximum cell growth was observed with glucose as carbon source at the concentration of 50 g/l at $37^{\circ}C$ with the initial pH 6.5. When B. longum was cultured in a cross-flow filtration system, the maximum cell growth was observed at a dilution rate(D) of $0.31\;h^{-1}$ and the dry cell weight was 16.4 g/l($3.5{\times}10^{10}\;cell/ml$), which was about four times higher than that obtained in the batch culture with pH control.