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이대우,Michael E. Adams 한국응용곤충학회 2022 한국응용곤충학회지 Vol.61 No.1
In this study, we have examined pyrethroid actions on sodium channels in the pest insect Heliothis virescens. The synthetic pyrethroid permethrin increased steady-state sodium current in H. virescens central neurons and prolonged tail currents (I Na-tail ) due to extreme slowing of sodum channel deactivation. Prolongation of I Na-tail was evident at permethrin concentrations as low as 60 nM, which modified ~1.7% of sodium channels and 10 μM permethrin modified about 30% of channels. The average time constant (τ 1 ) of tail current decay was ~335 ms for permethrin-modified channels. These modified channels activated at more negative potentials and showed slower activation kinetics, and failed to inactivate. Permethrin modification of sodium channels was dramatically potentiated by the α scorpion toxin LqhαIT, showing positive cooperativity between two binding sites. The amplitude of the tail current induced by 0.3 μM permethrin was enhanced ~8-fold by LqhαIT (200 pM). Positive cooperativity was also observed between permethrin and the insect-specific scorpion toxin AaIT as 10 nM permethrin potentiated the shift of voltage dependence caused by AaIT (~2-fold).
이대우 대한설비공학회 2000 설비저널 Vol.29 No.8
아직까지 국내에서는 정립되지 못한 건축 설비의 전과정평가(life cycle assessment)에 대하여 기술하고자 한다.
이대우,손정현,유완석 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.
Since the performance of a circuit breaker which has the spring operating mechanism mainly depends on the dynamic behavior ofa coil spring, the analysis of the dynamic behavior of a coil spring is required for a performance evaluation of a circuit breaker. Whena spring moves so fast from the releasing state, a lot of energy is used to move a self-weight of a spring. Thus, the mass effect analysisof a spring operating mechanism is required for the performance evaluation of a circuit breaker accurately. In this study, a releasetest bed is designed for evaluating the dynamic behaviors of a coil spring. Three types of spring models such as a linear spring model,a nodal spring model and a lumped parameter spring model are established for comparing the modeling error of a spring due tothe mass effect. RecurDyn is employed to carry out the computer simulation and results are compared with test results. The actualenergy transferred to the follower during high-speed motion is analyzed through the comparisons of the kinetic energy between theexperiment and the computer simulation.