두 종류의 스펙트럼영역 빛간섭단층촬영기를 사용한 정상 한국인의 맥락막 두께 측정의 재현성

이광현,이성철,이승규.Kwang Hyun Lee. MD. Sung Chul Lee. MD. Christopher Seungkyu Lee. MD 대한안과학회 2013 대한안과학회지 Vol.54 No.9

Purpose: To investigate the reproducibility of choroidal thickness measurements in healthy Koreans using two spectral domain optical coherence tomography (SD-OCT) instruments: Zeiss Cirrus HD-OCT (Carl Zeiss Meditec Inc., Dublin, CA, USA) and Heidelberg Spectralis (Heidelberg Engineering, Heidelberg, Germany). Methods: Images were obtained in 60 eyes of 30 healthy undilated volunteers without ocular pathology in a clinical setting. The choroid was imaged in all subjects using Cirrus HD 1-line raster and Spectralis enhanced depth imaging (EDI). The choroid was measured subfoveally, 1500 μm temporal, and 1500 μm nasal to the fovea. All measurements were performed by two independent observers. One-way analysis of variance (ANOVA), Pearson correlation, and Bland–Altman analysis were used to compare measurements. Results: The study group consisted of 15 males and 15 females. The mean age was 50.73 ± 15.09 years (range, 24-75 years). There was no significant difference in the mean choroidal thickness (p > 0.05) between systems for any location. The choroidal thickness measurements using two instruments (Cirrus vs. Spectralis) were also strongly correlated (p < 0.001). Conclusions: In the present study of healthy Korean adults, good reproducibility was observed between choroidal thickness measurements of images obtained from Cirrus and Spectralis.

손톱밑에 발생한 사구종의 치료

이광현,양문승,Lee, Kwang-Hyun,Yang, Mun-Seung 대한근골격종양학회 1995 대한골관절종양학회지 Vol.1 No.2

사구종 환자 8례중 단순 절제만으로 전례에서 동통 소실과 함께 종괴 제거 후 세심한 조상 봉합을 함으로써 손톱의 변형을 최소화 할 수 있었고, 수술시 손톱을 완전히 제거하지 않고 다시 제 위치에 고정함으로써 수술후 창상치료가 간편하였으며, 환자가 조기에 손가락을 사용하는데 불편함을 최소화 할 수 있었다. Glomus tumor is uncommon tumor with an incidence of about 1% in soft tissue tumors and the single most common location is the subungual region of the finger. Many reports have emphasized that glomus tumors were difficult to diagnose and that the result of surgical removal was good, but nail deformity has received little attention. Most of authors removed the entire nail or partially splitted the nail to exposure the nail bed and tumor. Nobody reported whether nail deformity after operation was present or not. But, an abnormal nail is both a cosmetic and a functional problem in that catches on objects. In this study, our attention was postoperative nail deformity as well as the results of surgical removal. Seven patients(eight cases) who were diagnosed as a subungal glomus tumor in the hand were treated by surgical excision without removal of the nail and followed over twenty two months. And then we report on our experience with 8 cases of subungual glomus tumor which were successfully treated by complete excision without nail deformity.

Application in Ultrafiltration and Reverse Osmosis Module Set with Acrylic Wastewater Pretreated by Coagulation-Filtration-Neutralization Process

이광현,강병철,이종백,Lee, Kwang-Hyun,Kang, Byung-Chul,Lee, Jong-Baek The Membrane Society of Korea 2008 멤브레인 Vol.18 No.1

After membrane fouling factors in acrylic wastewater were minimized by pretreatment process accompanied with coagulation-filtration-neutralization, it was utilized in UF/RO process. After composing of ultrafiltration and reverse osmosis module set according to types and kinds of membrane, the separation characteristics were examined with the variation temperature and pressure using pretreated acrylic wastewater by membrane module sets. It was found that permeate flux of UF module in module set 4 was about two${\sim}$three times larger than that of UF module in module set 1. Final quantity of permeate from the module set 2 and module set 3 combined with tubular module was shown very good result. It was shown that the removal efficiency of TDS, T-N and COD was very low and was not dependent on the variation of temperature and pressure in all UF modules. The removal efficiency of TDS, T-N and COD was very excellent in RO module. Final water quality of acrylic wastewater was satisfied with effluent allowances limit and membrane module sets were ascertained to reuse wastewater. 아크릴 폐수를 응집-여과-중화의 전처리 공정에 적용하여 막오염 인자를 최소화 한 후 UF/RO 공정에 적용하였다. 막의 형태 및 종류에 따라 한외여과 및 역삼투 모듈을 조합을 이루어 전처리 수를 온도 및 압력변화에 따라 적용하여 분리 특성을 고찰하였다. 투과 플럭스는 모듈 set 1의 UF모듈보다 모듈 set 4의 UF모듈의 투과량이 약 $2{\sim}3$배 더 많이 배출됨을 확인하였다. 최종적인 투과량은 관형모듈과 조합을 이룬 모듈 set 2와 모듈 set 3이 좋은 결과를 나타내었다. 모든 UF 모듈에서 TDS, T-N 및 COD의 제거 효율은 온도 및 압력변화에 영향을 받지 않고 제거 효율 또한 낮음을 알 수 있었다. RO모듈에서 TDS, T-N 및 COD가 우수한 제거 효율을 보였다. 아크릴 폐수의 최종적인 수질결과는 공장폐수의 배출 허용기준을 만족하였고, 막모듈 조합은 폐수의 재활용 가능성을 확인할 수 있었다.

자동차 주행 환경에서의 음성 전달 명료도와 음성 인식 성능 비교

이광현,최대림,김영일,김봉완,이용주,Lee Kwang-Hyun,Choi Dae-Lim,Kim Young-Il,Kim Bong-Wan,Lee Yong-Ju 대한음성학회 2004 말소리 Vol.50 No.-

The normal transmission characteristics of sound are hardly obtained due to the various noises and structural factors in a running car environment. It is due to the channel distortion of the original source sound recorded by microphones, and it seriously degrades the performance of the speech recognition in real driving environments. In this paper we analyze the degree of intelligibility under the various sound distortion environments by channels according to driving speed with respect to speech transmission index(STI) and compare the STI with rates of speech recognition. We examine the correlation between measures of intelligibility depending on sound pick-up patterns and performance in speech recognition. Thereby we consider the optimal location of a microphone in single channel environment. In experimentation we find that high correlation is obtained between STI and rates of speech recognition.

서버 부하 감소를 위한 P2P 기반 데이터 서비스 시스템의 설계 및 구현

이광현,전형수,유철중,장옥배,Lee, Kwang-Hyon,Jeon, Hyung-Su,Yoo, Cheol-Jung,Chang, Ok-Bae 한국정보처리학회 2002 정보처리학회논문지 C : 정보통신,정보보안 Vol.9 No.5

최근 흠 네트워킹에 대한 관심이 증가하면서 멀티미디어 클립서비스에 관한 연구가 진행되고 있다. 가정내 네트워크의 대역폭이 가지는 한계로 인해 클라이언트-서버 방식을 통한 대용량 멀티미디어 자료들을 장시간 동안 받아야하고 서버에 트래픽이 증가하는 문제점들이 나타나고 있다. 본 논문에서는 서버를 거치지 않고 가정과 가정을 직접 연결하여 자료를 교환할 수 있는 Peer-to-Peer(P2P) 기술이 적용된 자료공유 네트워크 시스템을 설계하였고 서버의 트래픽을 줄이도록 하였으며 Java 언어로 플랫폼 독립적인 시스템을 구현하였다. Recently, as interest in Home networking is increased, research about multimedia clip service is gone. Because of the limit to bandwidth of home network, the problem of server traffic is increased by transferring many multimedia data through Client-Sewer Way for long. The data share network system applied is designed and implemented to solve this problem. P2P is connected directly between clients and exchanges data without going through a sewer. We implemented platform-independent System using Java and applied P2P skill to reduce server traffic.

DLBCL 환자의 대사경로 정보를 이용한 생존예측

이광현,이선호,Lee, Kwang-Hyun,Lee, Sun-Ho 한국통계학회 2010 응용통계연구 Vol.23 No.4

마이크로어레이 실험 결과로부터 생존예측지표를 개발하는 일은 관찰 유전자수가 환자의 수보다 훨씬 많고 또 반응변수가 중도절단이 포함된 생존시간이기 때문에 어려운 작업이다. 또한 개별유전자 분석의 문제점이 대두되면서 동일한 대사기능을 수행하는 유전자들의 집합을 대상으로 분석하는 방법이 대두되고 있다. DLBCL 환자들의 마이크로어레이 유전자 발현 자료와 생존시간, 유전자들의 대사경로 정보를 바탕으로 생물학적 해석이 쉬운 생존예측지표를 찾고 그 정확성을 검정하는 pilot study를 실시하였다. 또한 유전자 걸러내기가 지표의 효율성에 미치는 영향력도 비교하여 보았다. Predicting survival from microarray data is not easy due to the problem of high dimensionality of data and the existence of censored observations. Also the limitation of individual gene analysis causes the shift of focus to the level of gene sets with functionally related genes. For developing a survival prediction model based on pathway information, the methods for selecting a supergene using principal component analysis and testing its significance for each pathway are discussed. Besides, the performance of gene filtering is compared.

Zero-Configuration을 이용한 무구속 Holter 심전도 데이터 고속 전송 시스템에 관한 연구

이광현,임준우,김영길,Lee, Kwang-Hyun,Yim, Jun-Woo,Kim, Young-Kil 한국정보통신학회 2010 한국정보통신학회논문지 Vol.14 No.2

의료기술의 발달과 인구의 고령화 및 생활양식의 변화로 건강에 관한 관심이 높아지고 있으며, 특히 의료 분야에서 헬스케어에 관한 연구가 활발하게 이루어지고 있다. 이러한 헬스케어 서비스를 제공하기 위해서는 생체 정보 수집센서에 관한 기술, 생체 신호 저장 기술, 저장된 데이터의 전송/분석이 필요하다. 본 연구에서는 이러한 헬스케어 서비스를 제공하기 위해 먼저 사용자의 행동을 보장할 수 있도록 많은 데이터를 저장할 수 있는 무구속 장치를 제안하였다. 그리고 저장된 데이터를 단 시간에 전송할 수 있는 방법에 대하여 연구하고 누구나 활용이 편리하게 자동으로 전송할 수 있는 시스템을 구현한다. Researches of Healthcare have been fulfilled lively with an advanced age and change of lifestyles. Especially, medical field has focused on researches of Healthcare due to that reasons. The Healthcare service requires the foundation technologies, such as sensor aggregating, data saving and data transmitting/analysis. In this research, we proposed the unrestricted equipment which can save a lot of aggregated patient's medical data to guarantee the patient's movement in Healthcare service. Moreover, we research the method which can transmit the aggregated data as soon as possible. Also, we implemented the system which can transmit the patient's medical data automatically for convenient use.

Yb:YAG 디스크로 레이저 표면 용융 경화된 SKD61 열간금형강의 경도와 미세조직에 미치는 레이저 출력의 영향

이광현,최성원,강정윤,Lee, Kwang-Hyeon,Choi, Seong-Won,Kang, Chung-Yun 대한용접접합학회 2015 대한용접·접합학회지 Vol.33 No.3

In this study, effect of laser power on hardness and microstructure of SKD61 Hot Die steel of which surface was melted and hardened with Yb:YAG disk laser was investigated. Beam speed was fixed at 70 mm/sec and distance between them was 0.8 mm about Laser surface melting. The only thing that was changed laser power. Laser powers were 2.0, 2.4 and 2.8 kW. No defect was found under all conditions. As the laser power increased, the penetration depth were deepened and the bead width was also widened. There was no hardness deviation of fusion zone at same laser power and it was higher than that of heat affected zone. In addition, the more laser power increased, the more hardness in fusion zone decreased. Fusion zone was macroscopically dendrite structure. However, core matric in dendrite was lath martensite of 100 nm size. There were $M_{23}C_6$ of 500 nm and the VC and $Mo_2C$ of a nano meters on boundary of dendrite.

자동차 환경에서의 노이즈 DB 및 한국어 음성 DB 구축

이광현,김봉완,이용주,Lee Kwang-Hyun,Kim Bong-Wan,Lee Yong-Ju 대한음성학회 2003 말소리 Vol.48 No.-

Researches into robust recognition in noise environments, especially in car environments, are being carried out actively in speech community. In this paper we will report on three types of corpora that SiTEC (Speech Information TEchnology & industry promotion Center) has created for research into speech recognition in car noise environments. The first is the recordings of 900 Korean native speakers, distributed according to gender, age, and region, who uttered application words in car environments. The second is the collections of mixed noise in 3 car types by model while setting up various noise patterns which can be obtained with the car engine on or off, at different driving speed, and in different road conditions with windows open or closed. The third is the recordings of simulated speech by HATS (Head and Torso Simulator) in car environments with the internal and external noise factors added. These three types of recordings were all made through synchronized 8 channel microphones that are fixed in a car. The creation and applications of these corpora will be reported on in detail.

근적외선 연속발진 레이저 조사에 의한 게르마늄 광학창 손상 연구

이광현,신완순,강응철,Lee, Kwang Hyun,Shin, Wan-Soon,Kang, Eung-Cheol 한국군사과학기술학회 2014 한국군사과학기술학회지 Vol.17 No.1

The damage in germanium (Ge) optical window irradiated by a near-infrared continuous wave (CW) laser was studied. Laser-induced heating and melting process were surveyed, and the specific laser power and the irradiance time to melt were estimated by numerical simulation. The experiments were also carried out to investigate the macro and micro structure change on Ge window. Results showed that the surface deformation was formed by melting and resolidification process, the damaged surface had a polycrystalline phase, and the transmittance as an optical performance factor in mid-infrared region was decreased. We confirmed that an abnormal polycrystalline phase and surface deformation effect such as hillock formation and roughness increase reduced the transmittance of Ge window and were the damage mechanism of CW laser induced damage on Ge window.