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      • KCI등재후보

        복부 및 골반 방선균증 1 예

        박철신(Cheol Shin Park),윤오주(Oh Joo Yune),이헌영(Heon Young Lee),김영건(Young Kun Kim),노흥규(Heung Kyu Ro),이복희(Bok Hee Lee) 대한내과학회 1989 대한내과학회지 Vol.36 No.2

        Actinomycosis is a chronic, progressive, Suppurative, granulomatous disease. Definite diagnosis will generally be based upon histologic identification of actinomycotic granules or culture of the Actinomyces, or both. The diagnosis of abdomino-pelvic actinomycosis is often difficult to make. Since abdominal actinomycosis is indeed an uncommonly encountered clinical entity today, many clinicians fail to consider actinomycosis as a possibility. Actinomyces is anaerobic. It is not usually isolated from routine cultures and anaerobic cultures are difficult to obtain. It may be impossible to clinically distinguish abdominal actinomycosis from other diseases because of the variable forms of presentation which may be recognized in patients, including fever, anorexia, nausea and vomiting. Especially in Korea, the clinical presentation of actinomycosis often resembles intestinal tuberculosis, which should not usually be treated surgically. We experienced a case of Abdomino-pelvic Actinomycosis in which it was difficult to make a early diagnosis.

      • KCI등재후보

        성인 급성골수성 백혈병의 DAV ( Doxorubicin Ara - C and Vp - 16 ) 복합화학요법

        박철신(Cheol Shin Park),김종완(Jong Wan Kim),송민호(Min Ho Song),조덕연(Deog Yeon Jo),윤오주(Oh Joo Yune),한성필(Sung Pil Han),김삼용(Sam Yong Kim) 대한내과학회 1989 대한내과학회지 Vol.36 No.3

        N/A To evaluate the therapeutic effect and usefulness of DAV combination chemotherapy, 12 patients with adult acute myelogenous leukemia were treated with a DAV (Doxorubicin 45 ㎎/㎡ 4, days 3-5, Ara-C 100 ㎎/㎡ 4, days 1-8 and VP-16 100 ㎎/㎡ 4, days 6-8) regimen for remission induction. The results were as follows: 1) The rate of complete remission was 10/13 (76.9%) including one case of re-induction chemotherapy. 2) The median remission duration and the median survival duration in-completely remitted patients were 8 months (1-16 months) and 10 months (2-25 months), respectively. 3) Two among the 9 remitted patients were relapsed (22%). 4) The 2-year survival rates of all patients, the completely remitted patients and the in-completely remitted patients were 33%, 50% and 0%, respectively. 5) The drug toxicities of grade 3 or more (grade 2 or more in anorexia, nausea and alopecia) according to ECOG (Eastern Cooperative Oncology Group) toxicity criteria were as follows: leukopenia-11/12 (92%), anorexia and nausea-8/12 (67%), alopecia-8/12 (67%), mucositis and stomatitis-7/12 (58%) and hemorrhage-5/12 (42%). Thus, we conclude that DAV combination chemotherapy is one of the useful and encouraging therapeutic regimens in remission induction of adult acute myelogenous leukemia.

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