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      • KCI등재

        벤처기업 경영자 특성이 경영성과에 미치는 영향에 관한 연구;대덕연구개발특구를 중심으로

        윤보현,박준병,Yoon, Bo-Hyun,Park, Joon-Byoung 한국벤처창업학회 2007 벤처창업연구 Vol.2 No.3

        Current researches have been proceed on CEO's Characteristics of venture business because the CEO has considered as one of the important factors for the success of venture business. But prior research on the performance of venture business has produced inconsistently in terms of CEO's characteristics. The purpose of this study is to develop a comprehensive model for the relation between the performance and a type of CEO's characteristics by a growth process of venture business, which is the main subject of analysis in venture business. Also, this study analyzes various CEO's characteristics and the effects for performance of venture business which are in the Daedeok valley. To achieve the purpose of this research, an empirical study by using research model and hypotheses including the general characteristics of venture business and CEO's demographic characteristics has been presented as a research method for relation analysis. The principal findings of the research and its significance are summarized as follows: First, it was found that there is a significant different in the performance of CEO's behavioral characteristics by the scale, type and growing step of organization for venture business. Second, it was found that there is not a significant between an academic career, management experience, foundation experience for business and related working experience of venture CEO and the performance, but there os a partially significant difference in CEO's behavioral characteristics. Third, it was found that there is a partially significant difference between CEO's behavioral characteristics of venture business and the performance by the general characteristics of organization for venture business and demographic characteristics. In conclusion, in spite of the insufficient research for venture business in Daedeok, the implications of theses findings and contributions made by this research is to confirm the characteristics factor of CEO for venture business and general characteristics of organization for venture business by multidisciplinary side. In addition, the findings provide the basis for the analyzing of managerial strong point and weak point referred to supporting system for venture business. Finally, the findings of this study suggest that the results should be a useful data for groping a solution for upbringing plans in terms of a long-term point of view.

      • KCI등재

        정상성인에서 ALDH-I의 변이가 알콜의 정신운동성 수행과 주관적 평가에 미치는 영향

        윤보현,윤진상,Yoon, Bo Hyun,Yoon, Jin Sang 대한생물정신의학회 1996 생물정신의학 Vol.3 No.2

        The purpose of this study was to evaluate the effects of alcohol on the psychomotor performance and subjective assessment in healthy Korean adults with acetaldehyde dehydrogenase I(ALDH-I) isozyme variance. A total of 20 male subjects, half with active ALDH-I and the other half with inactive ALDH-I, were selected through both a self-reporting questionnaire examining alcohol sensitivity and the Higuchi's ethanol patch test detecting ALDH-I deficiency. In a doule-blind, placebo-controlled cross-over design, each subject consumed four doses of alcohol(0.25, 0.5, 0.75, 1.0g/kg) and placebo on five separate occasions at weekly intervals, Treatment order was fully balanced using a $5{\times}5$ Latin square, Psychomotor performance tests[coritical flicker fusion threshold(CFF) and choice reaction time(CRT)] and self-estimate questionnaires were conducted at baseline and at time points of 20, 40, 60, 90, 120, 150, 180 minutes after consuming the test drug for 20 minutes, Blood alcohol concentrations(BACs) using breath analyzer were measured at baseline and at time points of 10, 20, 30, 40, 50, 60, 75, 90, 105, 120, 150, 180 minutes after drinking, The BACs and the mean changes in the psychomotor performances and subjective assessments from pre-alcohol baseline, were compared between the two groups. The findings were summarized as follows : 1) BACs were tended to be higher in the inactive group than the active in all of the four alcohol doses. However significant group differences were only after the 0.5g/kg dose of alcohol. 2) The inactive group showed significant impairment in CFFT at most time points alter 0.75 and 1.0g/kg doses of alcohol. 3) In CRT, total reaction time(TRT) significantly prolonged in the inactive group than the active group at 20 minutes after 0.25 and 1.0g/kg doses of alcohol and at 40, 60, 90 minutes alter 0.75g/kg dose of alcohol. In the inactive group, recognition time component significantly increased at 20, 60, 90 minutes after 1.0g/kg dose of alcohol, while movement time component significantly increased at 40, 60 minutes after 0.75g/kg dose of alcohol. 4) Subjective evaluation of the effect of alcohol revealed that physical and mental conditions as well as a self-estimate of the effects of alcohol on performance were significantly worse in the inactive group than the active at some time points alter all of the lour alcohol doses, wihch were more pronounced after 0.75 and 1.0g/kg doses of alcohol. 5) Most of the group differences mentioned above, still remained statistically significant after BAC was entered as a covariate, These findings demonstrated that the alcohol sensitivity is higher in individuals with inactive ALDH-I than those with active ALDH-I both on the subjective assessments and the objective psychomotor performances. Furthermore, these results suggest thai the alcohol sensitivity may be determined by acetaldehyde concentration rather than BAC per se. In future studies, after more accurate genotyping for ALDH-I, the relationships between BAC, acetaldehyde concentration and alcohol sensitivities should be clearly defined. ALDH-I 활성군과 비활성군에서 음주후 정신운동성 수행 및 주관적 평가에 미치는 영향을 비교하였다. 사교적 음주에 상응하는 4종류의 알콜(0.25, 0.5, 0.75, 1.0g/kg)을 투여한 결과 비활성군이 활성군에 비해 보다 부정적인 평가를 하였다. 이는 특히 고용량의 알콜(0.75 및 1.0g/kg)을 투여시 분명하였다. 이러한 결과는 비활성군이 활성군에 비해 알콜에 대한 민감성이 주관적인 판단과 객관적인 수행에서 모두 더 높다는 사실을 반영한다.

      • KCI등재

        호흡음주측정에서 Alco-Sensor Ⅳ와 Lion Alcolmeter SD-400P의 비교

        윤보현(Bo-Hyun Yoon),정명섭(Myung-Sub Jung),표경식(Kyung-Sik Pyo),임채식(Chae-Sig Lim),이병회(Byung-Hoi Lee),박용현(Yong-Hyun Park) 한국중독정신의학회 1999 중독정신의학 Vol.3 No.1

        Objectives:The aim of this study was to evaluate the interreliabilities and reproducibilities of two breathanalyzers which commonly used in clinical settings, research fields, and legal purposes including roadside testing. Methods:Thirty-four healthy male volunteers were examined through 30, 60, 90, 120, 150 and 180 minutes after 20 minutes’ intake of one of the two doses of alcohol (0.5 and 0.75 g/kg of body weight) on separate occasions. Two kinds of breathanalyzers [Alco- Sensor Ⅳ (Intoximeters, Inc., USA;Alco-Sensor) and Lion Alcolmeter SD-400P (Lion Laboratories plc, UK;SD-400P)] were used to measure the breath alcohol concentrations (BrAC). Duplicate breath samples at each time point were used to determine the repeatabilities of the breathanalyzers. Results:Mean values of two breathanalyzers at each time point were not statistically different. Although there were not significant, the values obtained from SD-400P were tended to slightly higher than those of Alco-Sensor. Inter-reliabilities of Alco-Sensor and SD-400P at 0.5 and 0.75 g/kg of body weight were very high[r=0.972 (p〈.001);r= 0.938 (p〈.001), respectively]. Test-retest reliabilities of Alco-Sensor and SD- 400P were also very high[r=0.976 (p〈.001); r=0.984 (p〈.001), respectively]. Conclusion:The two breathanalyzers can be used as highly reliable instruments in all kinds of fields including roadside testing. Although further studies concerning the accuracy and precision of the breath-alcohol measurements in Koreans should be done, it suggests that these instruments may be easily and safely used as evidential breath testing.

      • KCI등재SCOPUS
      • KCI등재

        한국 주식시장에서의 대안 인덱스투자전략 연구

        윤보현 ( Bo Hyun Yoon ),최영민 ( Young Min Choi ) 한국파생상품학회(구 한국선물학회) 2014 선물연구 Vol.22 No.2

        본 연구는 주식시장의 시가총액 비중 시장 인덱스의 위험 대비 수익률 관점의 비효율을 지적하며 등장한 다양한 대안적인 인덱스 투자전략을 한국 주식시장에 적용하여 실증 분석한다. 대안 인덱스 투자전략이란 인덱스를 구성하는 종목의 비중 계산을 시가총액 비중이 아닌 재무제표를 이용하거나, 평균-분산 최적화 결과를 이용하는 등의 방법을 이용하는 것으로 한국 주식시장에서 포트폴리오를 구성하여 수익률을 측정한 결과, 시장 인덱스보다 위험 대비 수익률의 효율성이 증대함을 확인하였다. 또한 대안인덱스의 초과수익률은 Fama-French의 3요인 분석 결과 시장요인 및 기업규모요인 그리고 가치요인의 세 가지 요인으로 설명이 가능한 것으로 나타났다. 하지만, 이 사실이 대안 인덱스의 유용성을 해친다고 할 수는 없다. Fama-French의 기업규모요인이나 가치요인은 매수/매도 포지션으로 이루어져있고, 포트폴리오 재구성 시 높은 수준의 시장충격이 발생할 가능성이 높기 때문이다. 본 연구는 이러한 측면에서 대안 인덱스가 100% 매수 포지션으로만 이루어져 있고 회전율도 높지 않기 때문에 기업규모요인이나 가치요인을 실질적으로 투자가능하게 만들어주는 순기능이 존재할 수 있음을 제시하였다. There have been several studies of alternative equity index strategies which suggest better investment opportunities with higher risk adjusted return pointing out empirical evidence of inefficient risk-return trade-off implied in the market-cap weighted index. Commercial products based on these strategies, regarded as passive equity strategies, become more popular in the U.S. and European stock markets. We investigates whether these strategies are also valid in Korean stock market and our empirical results add support to their efficacy. From Fama-French 3-factor analysis, we find that the excess return of alternative equity index is attributed to market, size and value factors and it does not show a significantly positive alpha. Even without positive alpha, however, these strategies are valuable to investors in the sense that they offer opportunities to fully exploit size and value premium with long-only portfolios. The advantage of these strategies is more straightforward recalling the fact that rebalancing of Fama-French factor portfolios involves short-sale and high turnover.

      • KCI등재
      • KCI등재SCOPUS

        산과적 출혈의 처치에 있어서 경피적 혈관색전술의 이용

        윤보현(Bo Hyun Yoon),김미하(Mi Ha Kim),신희철(Hee Chul Syn),문정빈(Jeong Bin Moon),전종관(Jong Kwan Jun),오수영(Soo Young Oh),박중신(Joong Shin Park),김석현(Seok Hyun Kim),이택상(Taek Sang Lee),정진욱(Jin Wook Chung),박재형(Jae Hyung 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.7

        Objective : To investigate whether emergency selective arterial embolization may serve as a safe and effective alternative treatment in the management of intractable pregnancy-associated hemorrhage. Methods : Between February 1992 and March 1999, 20 patients at Seoul National University Hospital underwent angiographic embolization to control obstetrical hemorrhage. In all cases, hemostatic embolization was performed because of intractable hemorrhage unresponsive to conservative management. All available hospital records were reviewed and detailed to collect adequate clinical data such as specific leading complication, clinical status, estimated blood loss and blood replacement requirements, length of procedure, used emboli, complications associated with the procedure, and its results. Results : We have experienced the successful embolization in 18 of 20 patients of pregnancy-related hemorrhage from the different causes. One of these successful cases required two embolization attempts. Two of these patients needed surgical treatment because of rebleeding after the embolization. The mean length of the time for the procedure was 96.4±50.1 minutes (range; 50-260 min.). The average length of hospitalization was 10.4±7.7 days (range; 1-36 days). No major complication related to the embolization was found. Two women became pregnant after embolization. Conclusion : This study indicates that angiographic embolization is a safe and effective method for the control of pregnancy-related hemorrhagic complications unresponsive to conservative management and that it allows maintenance of reproductive ability.

      • KCI등재SCOPUS

        조기양막파수 산모에서 중합효소 연쇄반응 기법을 이용한 양수내 Ureaplasma urealyticum 의 검출과 양수내 염증성 반응 및 주산기 예후와의 연관성

        윤보현(Bo Hyun Yoon),이희선(Hee Sun Lee) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.6

        Objective : The aim of this study was 1) to determine the clinical significance of isolation of Ureaplasma urealyticum (U urealyticum) by polymerase chain reaction (PCR) in amniotic fluid and 2) to identify the association of positive result of PCR for U urealyticum with maternal and intraamniotic inflammatory response in patients with preterm premature rupture of membrane (PROM). Methods : Amniocentesis was done in 131 patients with preterm PROM during the period from January, 1994 to January, 1998. Amniotic fluid was cultured for bacteria and mycoplasmas. PCR with primer for U urealyticum was performed. Patients were divided three groups according to the results of amniotic fluid culture and PCR for U urealyticum: those with a negative amniotic fluid culture and negative PCR (group 1, n=84), those with a negative amniotic fluid culture but positive PCR (group 2, n=12) and those with a positive amniotic fluid culture (group 3, n=35). Results : 1) U urealyticum was isolated in 18.3% (24/131) by conventional culture method and in 26.7% (35/131) by PCR. 2) Patients with a negative amniotic fluid culture but positive PCR for U urealyticum (group 2) had significantly higher amniotic fluid white blood cell (WBC) count and higher rate of funisitis than those with a negative amniotic fluid culture and negative PCR (group 1) (amniotic fluid WBC: median 169 [1-2,295] cells/㎣ vs median 1 [0-7,956] cells/㎣ p<.001; funisitis: 71.4%[5/7] vs 24.6%[15/61], p=0.02). 3) Patients with a negative culture but positive PCR for U urealyticum (group 2) had higher rate of congenital infectious morbidity and bronchopulmonary dysplasia in their babies than those with a negative culture and negative PCR (group 1) (congenital infectious morbidity: 36.4% [4/11] vs 11.4% [9/79]; bronchopulmonary dysplasia: 27.3% [3/11] vs 2.5%[2/79], p<0.05 for each). 4) No significant differences in perinatal outcome were observed between patients with a negative culture but positive PCR (group 2) and those with a positive amniotic fluid culture (group 3). Conclusion : Isolation of U urealyticum by PCR in amniotic fluid is associated with an intense intraamniotic inflammatory response and adverse perinatal outcomes in patients with preterm premature rupture of membranes.

      • KCI등재SCOPUS
      • KCI등재SCOPUS

        한국인 산모에서 임신중기 양수내 alpha-fetoprotein치의 정상 범위

        윤보현(Bo Hyun Yoon),김미하(Mi Ha Kim),신희철(Hee Chul Syn),문정빈(Jeong Bin Moon),전종관(Jong Kwan Jun),임준희(June Hee Lim),오수영(Soo Young Oh),이용희(Yong Hee Lee),박중신(Joong Shin Park) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.6

        Objective: Our purpose was to determine normal amniotic fluid α-fetoprotein level in midtrimester Korean pregnant women whose neonatal outcomes were normal. Methods: Amniotic fluid α-fetoprotein(AFAFP) levels were measured by specific radioimmunoassay (RIA) in midtrimester pregnant women for various indications of amniocentesis from May 1992 to July 1999 at Seoul National University Hospital. Normal ranges were obtained from 640 singleton pregnancies in which neonatal outcomes were normal.Results: Median values of AFAFP in Korean pregnant women were 13,250ng/mL, 12,900ng/mL, 11,150ng/mL, 9,430ng/mL, 8,019ng/mL, 6,800ng/mL, 5,850ng/mL, 5,750ng/mL, 5,210ng/mL, 3,420ng/mL at 15 week, 16 week, 17 week, 18 week, 19 week, 20 week, 21 week, 22 week, 23 week, 24 week, respectively.Conclusion: This determination of the median values and the normal range of AFAFP level by each gestational week in uncomplicated Korean women could be used reference values for prenatal diagnosis of various disorders like open neural tube defect.

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