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유창희,오철영,김세중,김선일,김영식,박종연,두승환,송윤섭,양원재,정현철,조인래,조성용,전상현,홍성준,조진선,성도환 대한비뇨의학회 2012 Investigative and Clinical Urology Vol.53 No.6
Purpose: To identify potential predictive factors of incidental prostate cancer (IPca) in patients considering tissue-ablation treatment for benign prostatic hyperplasia (BPH). Materials and Methods: From the 11 centers, 1,613 men who underwent transurethral resection of the prostate (TURP) or open prostatectomy were included. Before surgery, prostate biopsy was performed in all patients with prostate-specific antigen (PSA) ≥4.0 ng/ml or with abnormal digital rectal examination (DRE) findings. The patients with prostate cancer preoperatively or with PSA >20 ng/ml were excluded. As predictive factors of IPca, age, body mass index, PSA, DRE, and transrectal ultrasonography (TRUS) findings, including total prostate volume (TPV), transition zone volume (TZV), and the presence of hypoechoic lesions, were reviewed. PSA density (PSAD) and PSAD in the transition zone (PSAD-TZV) were calculated. Results: IPca was diagnosed in 78 patients (4.8%). DRE findings, PSA, and TZV were independent predictive factors in the multivariate analysis. In the receiver operating characteristic curve analysis of PSA, PSAD, and PSAD-TZV, the area under the curve (AUC) was the largest for PSAD-TZV (AUC, 0.685). Conclusions: IPca was detected in 4.8% of the population studied. In addition to DRE findings, the combination of TZV and PSA can be useful predictive factors of IPca in patients considering tissue-ablation treatment as well as TURP.
냉각 및 저장온도를 달리한 가정배달급식용 불고기의 저장 기간 중 이화학적, 미생물적 품질 변화
유창희,이경은 (사)한국조리학회 2019 한국조리학회지 Vol.25 No.10
The purpose of the study was to compare changes of quality characteristics of Bulgogi prepared for home-delivered meal service during storage by cooling method and storage temperature. Bulgogi was prepared and it was blast chilled or cooled at room temperature, and each sample was storage at 4℃ and −10℃ for physiochemical and microbiological quality testing. On completion of preparation, the Hunter color L-value was lower in Bulgogi cooled at room temperature than that blast chilled and it increased significantly as the storage period increased. The pH showed a significant increase as the storage period progressed. The TBARS value, which indicates lipid oxidation, increased over the storage period and was higher at storage of 4℃ than at storage of −10℃. Texture analysis showed that cohesiveness and hardness increased significantly over the storage period. Chewiness of blast chilled Bulgogi was significantly lower than that cooled at room temperature (p<0.001). During storage, standard plate count and coliforms count ranged 0.5~2.9 logCFU/g, which fall within safe ranges(≤5 logCFU/g). Psychrophilic bacteria were detected in samples stored at 4℃ on day 5. In this study, we developed a recipe for home delivery of Bulgogi, whose meat is rich in nutritional value and has potential hazards in handling. The aim of this study is to provide the basic data for establishing a system for the production and storage of safe home delivery bulgogi by measuring changes in physicochemical and microbial quality during the period.
유창희,오철영,조진선,송채린,서성일,안한종,황태곤,천준,이강현,권태균,정태영,정문기,이상은,이현무,이은식,최영득,정병하,김형진,김원재,변석수,최한용 대한의학회 2011 Journal of Korean medical science Vol.26 No.4
We investigated the clinical significance of large difference (≥ 2 points) between biopsy-derived (bGS) and post-prostatectomy Gleason scores (pGS). At 14 medical centers in Korea, 1,582 men who underwent radical prostatectomy for prostate cancer were included. According to the difference between bGS and pGS, the patients were divided into three groups: A (decreased in pGS ≥ 2, n = 30), B (changed in pGS ≤ 1, n = 1,361; control group), and C (increased in pGS ≥ 2, n = 55). We evaluated various clinicopathological factors of prostate cancer and hazards for biochemical failure. Group A showed significantly higher mean maximal percentage of cancer in the positive cores (max%) and pathological T stage than control. In group C, the number of biopsy core was significantly smaller, however, tumor volume and max%were significantly higher and more positive biopsy cores were presented than control. Worse pathological stage and more margin-positive were observed in group A and C than in control. Hazard ratio for biochemical failure was also higher in group A and C (P = 0.001). However, the groups were not independent factors in multivariate analysis. In conclusion, large difference between bGS and pGS shows poor prognosis even in the decreased group. However it is not an independent prognostic factor for biochemical failure.
Design and Evaluation of Performance Tester for Yaw Brakes in Wind Turbines
유창희,박진환,박상신 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.5 No.1
In this study, a new type of test equipment is proposed to verify the performance of yaw brakes. A Nacelle, one of the wind turbine unit, rotates every 15 minutes to adjust its position to perpendicular to the blowing wind, which is known for yawing motion. The nacelle contains a main shaft, a gear box, and a generator, so that the size and weight are huge. A yaw brake system is the main device to stop the rotating nacelle during the yawing motion. A big disc of which the diameter is about 2 meters and several brakes are installed at the bottom part of the nacelle. Due to the difficulty of the size, the performance test for the yaw brake is very difficult. New tester is designed using a partial disk to simulate the disk brakes in the nacelle, as well as the application of braking force by a hydraulic actuator located at double the radius of the disk in order to reduce the hydraulic power. The stresses and strains are calculated through CAE analysis, and the values are compared with those from strain gage tests. After verifying the performance of the tester and testing two kinds of brake pads, it is found that alumina and chromite increase the friction coefficients but produce vibration and sound noise.