갑상선 분화암 환자의 경과 관찰에서 수술 전 , 후 혈청 갑상선글로불린 측정의 유용성

원종철,이은주,이성진,문대혁,김상욱,류진숙,안일민,홍석준,한정희,김하영 대한내분비학회 2000 Endocrinology and metabolism Vol.15 No.4

Background: Thyroglobulin (Tg) measurement is primarily used to monitor patients with well differentiated thyroid carcinomas (WDTC) for tumor recurrence. We evaluated the correlations between fold responses of thyroglobulin levels and TNM stages (and MACIS scores) at recurrent group. Also correlations between preoperative Tg levels and Tg (on or off replacement) levels at the time of recurrence were evaluated. Postoperative Tg levels between recurrent and non-recurrent groups were analyzed for the use of assessing risk of recurrence. Methods: One hundred twenty five cases of WDTC who had total thyroidectomy and (131)I remnant thyroid ablation were finally included in this study. After optimal TSH stimulations ($gt;30 μIU/mL), (131)I whole body scan (WBS) was performed. We interpreted as a recurrence only when abnormal findings on the (131)I WBS were detected. Preoperative, immediate postoperative and follow-up Tg tlevels were regularly measured. Results: Difference of preoperative Tg levels between recurrent an non-recurrent groups was not significant (27.5±4.2 ng/mL vs. 16.0±10.9 ng/mL). Also differences of immediate postoperative Tg (on or off replacement) levels between two groups was not significant (2.4±3.8 ng/mL vs. 3.6±3.l ng/mL, 33.4±4.8 ng/ml vs. 24.5±4.8 ng/mL, respectively). Tg levels on replacement at 24 months after surgery between recurrent and non-recurrent groups were significantly different (2.2±4.8 ng/mL, 15.9±6.5 ng/mL, p$lt;0.001) and also Tg levels off replacement between recurrent and non-recurrent groups were significantly different (4.0±6.6ng/mL vs. 49.4±9.3 ng/mL, p$lt;0.001). Fold responses between recurrent and non-recurrent groups were significantly different (2.0±3.1 ng/mL, 5.0±4.1 ng/mL, p=0.009). Fold responses between recurrent and non- recurrent groups were significantly different according to TNM stages (p=0.002) but not different according to MACIS scores. Preoperative Tg levels were correlated Tg (on or off replacement) levels at the time of recurrence (p=0.02, r=0.4: p$lt;0.0espectively). Sensitivity, specificity, accuracy of Tg levels over 2 ng/mL on replacement were 95%, 73%, 84% but those of Tg levels over 7 ng/mL off replacement were 83%, 70%, 77%. Conclusion: Fold responses may predict prognosis of WDTC. Small postoperative increase in serum Tg levels may indicate a large increase of tumor mass in cases of normal or low preoperative Tg levels. Tg levels over 2 ng/mL on replacement or 7 ng/mL off replacement during follow-up may suggest the recurrence of WDTC (J Kor Soc Endocrinol 15:542-553, 2000).

보건소정보시스템 사용자 만족도 평가 및 관련요인 분석

원종철,배자성,이홍재,이재동,나백주,최희주 대한의료정보학회 2004 Healthcare Informatics Research Vol.10 No.1

The PHIS(Public Health Information System) has been developed, and installed in public health centers nationwide since 1994. Ironically, however, even though infrastructures have been modernized, there is scant published material that has investigated the determinants of success of the PHIS. Therefore, these were evaluated in relation to the concern of user satisfaction, which was composed of overall satisfaction, usability, convenience and satisfaction for the supportive system. These satisfaction factors were also compared according to general user characteristics. The questionnaire response rate was 81.5%. The overall satisfaction and total Likert's scores, 3.078±0.634 and 3.005±0.563, respectively, showed that the end-users were relatively satisfied with the PHIS. Also, the overall satisfaction correlated most strongly with the convenience attribute. However, dissatisfaction strongly correlated with the supportive system, i.e. education and training facilities. This article describes our progress, and reports on the lessons learned, which will guide future work in this field.

Diabetes Fact Sheet in Korea, 2016: An Appraisal of Current Status

원종철,이재혁,김재현,강은석,원규장,김대중,이문규 대한당뇨병학회 2018 Diabetes and Metabolism Journal Vol.42 No.5

Background: This report presents the recent prevalence and comorbidities related to diabetes in Korea by analyzing the nationally representative data. Methods: Using data from the Korea National Health and Nutrition Examination Survey for 2013 to 2014, the percentages and the total number of subjects over the age of 30 years with diabetes and prediabetes were estimated and applied to the National Population Census in 2014. Diagnosis of diabetes was based on fasting plasma glucose (≥126 mg/dL), current taking of antidiabetic medication, history of previous diabetes, or glycosylated hemoglobin (HbA1c) ≥6.5%. Impaired fasting glucose (IFG) was defined by fasting plasma glucose in the range of 100 to 125 mg/dL among those without diabetes. Results: About 4.8 million (13.7%) Korean adults (≥30 years old) had diabetes, and about 8.3 million (24.8%) Korean adults had IFG. However, 29.3% of the subjects with diabetes are not aware of their condition. Of the subjects with diabetes, 48.6% and 54.7% were obese and hypertensive, respectively, and 31.6% had hypercholesterolemia. Although most subjects with diabetes (89.1%) were under medical treatment, and mostly being treated with oral hypoglycemic agents (80.2%), 10.8% have remained untreated. With respect to overall glycemic control, 43.5% reached the target of HbA1c <7%, whereas 23.3% reached the target when the standard was set to HbA1c <6.5%, according to the Korean Diabetes Association guideline. Conclusion: Diabetes is a major public health threat in Korea, but a significant proportion of adults were not controlling their illness. We need comprehensive approaches to overcome the upcoming diabetes-related disease burden in Korea.

장자 「제물론」(齊物論)의 화합(和合) 사상 연구

원종철 가톨릭대학교 인간학연구소 2001 인간연구 Vol.- No.2

인간과 그룹과 인격형성

원종철 가톨릭대학교(성심교정) 인간학연구소 2001 인간연구 Vol.- No.2

그룹 다이내믹 : 협동학습의 교육원리에 관한 심리학적 연구

원종철 한국교육학회 2001 敎育學硏究 Vol.39 No.2

본 논문은 협동학습의 교육원리를 심리학적 입장에서 분석한 문헌 연구이다. 본 논문은 그룹 다이내믹에 대한 사회심리학 연구 결과들을 토대로 학습에서의 소그룹의 효과성과 협동학습이 심리학적 원리를 설명함으로써 협동학습의 이론적 기반을 다지려는 것이다. 첫째로 Kurt Lewin(1890-1947)에 의해서 시작된 그룹 다니내믹 연구의 역사를 추적하여 협동학습의 근원적이고도 이론적 바탕이 되는 그룹 다니내믹의 학문적 배경을 살펴보고, 둘째로 그런 학문적 역사 속에서 탄생한 협동학습을 그룹 다니내믹의 시각에서 분석하여 협동학습의 성과와 그것의 근본 교육원리가 무엇인지를 밝히려는 것이다. 이를 통해 본 논문은 소그룹을 통한 협동학습이 교육방법적으로 효과가 있을 뿐만 아니라 전인교육과 인성교육에 도움이 되는 이유가 근거를 밝히려는 것이다.

감성과 이성

원종철 가톨릭대학교 인간학연구소 2000 인간연구 Vol.- No.1

1M.L.F. 공정을 사용하여 매립지 침출수에서 질산화와 탈질산화에 미치는 재순환 비율과 수압의 비율의 영향

원종철,이정우,이환규,남궁완,윤조희 한국폐기물자원순환학회 2002 APLAS Vol.2002 No.2

파일럿 스케일의 MLE 공정을 이용하여, 수도권매립지로부터 발생하는 약 1,500~2,000mg/L의 높은 농도의 NH4+-N을 포함한 침출수의 생물학적 질산화와 탈질산화의 재순환 비율과 수압 비율의 변화의 영향을 조사한다. 본 실험의 결과, 약 600%의 재순환 비율과 BOD/NH4+-N의 비가 약 3.0인 조건에서, 약 탈질산화 탱크에서는 2.3일, 질산화는 5.7일이 NH4+-N의 99%와 T-N 80%의 제거효율을 얻기 위한 적당한 HRT이다. 또한, 탈질산화와 질산화의 적절한 미생물농도를 유지하면서, 최대 질소 제거 효율을 얻기 위한 적절한 재순환 비율은 외부 순환에 200%이고 내부순환이 400%이다. T-N과 NH4+-N에서 제거할 수 있는 최대 질소량은 각각 0.55kgT-N/kgVSS/day와 0.07kgT- N/kgVSS/day이 다. T-N을 제거하기 위해 소비되는 알칼리량(△ 알칼리성/△T-N)은 약 5.0이다. We examined the effects of change in hydraulic loading rate and recycle ratio at the time of biological denitrification and nitrification of leachate containing NH4+-N with high concentration about 1,500~2,000 mg/L which is generated from SUDOKWON landfill site using pilot-scaled MLE(modified ludzack ettinger) process. As a result of this examination, we found out that about 2.3 days in denitrification tank and 5.7 days in nitrification are the proper HRT for obtaining the removal efficiency of about 80 % for T-N and 99% for NH4+-N at the conditions of recycle ratio of about 600 % and BOD/NH4+-N ratio of about 3.0. In addition, proper recycle ratio for obtaining the maximum nitrogen removal efficiency while keeping proper microbe concentration in nitrification and denitrification tank was 200 % for external recycle and about 400% for internal recycle. The maximum nitrogen quantities to be removed for each load of T-N and NH4+-N are 0.055 kgT-N/ kgVSS/day and 0.07 kgNH4+-N/kgVSS/day, respectively. Alkalinity quantity (△ alkalinity/△ T-N) to be consumed for removal of T-N was found to be about 5.0.

교육학적 입장에서의 효 사상

원종철 신학과사상학회 2000 가톨릭 신학과 사상 Vol.- No.34

조직과 본당 신부의 리더십

원종철 신학과사상학회 1997 가톨릭 신학과 사상 Vol.- No.21