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      • KCI등재

        인태반 Alkaline Phosphatase에 관한 조직학적 연구

        옹상길(SK Ong) 대한산부인과학회 1965 Obstetrics & Gynecology Science Vol.8 No.12

        To study the physiological functions of the human placenta, the histochemical determination of alkaline phosphatase in the placenta as one of the enzymological studies was done. Forty placentas of normal pregnancy from the beginning to the overterm, and nineteen placentas of abnormal pregnancy-6cases of the spontaneous abortion at relatively early stages including incomplete and missed abortion, 3 cases of the intrauterine fetal death, 5 cases of toxemia of pregnancy, 2 cases of placenta previa partialis, and 3 cases of chorionic tumors were taken at Han-Ⅱ Hospital since March till October 1965. In normal pregnancy, the activity of alkaline phosphatase in the placenta was gradually increased to its peak at the 6th month of pregnancy and maintained to the term. The brush border of the syncytial cells at the early stages had the most stron activity, especially around th lacunae. The syncytial cells after 15-16th week of pregnancy got even distribution in their inner side of cytoplasms by degree along the placental aging. The variabilities and differences of stains in each villi which were shown at the early stages, were lost after the third month of pregnancy. The overterm placentas had weaker activity than the term. The placentas of spontaneous abortion at the early stages before the second half of the mid-trimester had lost their stains in general and more from the brush border, comparing with same agine ones. The placentas of the intrauterine fetal death and the severe toxemia of pregnancy were also remarkably less stained. The chorionic tumors were strongly stained but very variable in several regions.

      • KCI등재

        한국인 모유에 관한 면역학적 연구 ( 제 2편 ) 정상모유에 함유된 Immunoglobulin의 정성분석

        이성근(SK Lee),권영조(YJ Kwon),옹상길(SK Ong) 대한산부인과학회 1966 Obstetrics & Gynecology Science Vol.9 No.11

        Quantitative measurement of the IMMUNOGLOBULINS in the milk of the Korean women was performed using IMMUNO-PLATE Human γM, γG, γA Immunoglobulin Test. Seven cases of normal women were followed up, whose sera and colostrums were measured for the immunoglobulins in the previous paper. The levels of the immunoglobulins in the mature milk were as follows; IgG 40.6 17.3mg%; IgA 53.9 19.3mg%; IgM 20.0 9.0mg%. The content in the milk was much lowered as compared with that of the colostrum, and any fraction of the immunoglobulins in the milk did not exceed those in the maternal serum and colostrum.

      • KCI등재

        한일병원에서 방사선조사 ( Cs137원격조사,Radium강내조사 ) 에 의한 자궁경암 치료 ( 제 2보 )

        신웅호(WH Shin),강영호(YH Kang),옹상길(SK Ong) 대한산부인과학회 1966 Obstetrics & Gynecology Science Vol.9 No.11

        In the first section(basic section) of this report, the physical characteristics and biologic effects of Cs137 in comparison with Co60 and X-ray as the external irradiation therapy, and the advantages and the method of dosage calculation in use of TAO(Tasaki, Arai, Otachi) applicator, the afterloading technic of Ra, as the internal irradiation therapy were dicussed. Cs137 and Co60 are more excellent in their therapeutic effects than conventional x-ray. Cs137 has longer half-life, less penumbra, ease in protection, and costs low for its installation, but has lower energy level with less depth dose and dose rate. In calculation of Ra dosage, two methods were adopted instead of mg. hr or mC. hr which were less valuable for accurate biologic effects. Unit of R(Roentgen) in bilateral points A&points B was calculated. In the second section(clinical section), 167 cases from 181 cases who were admitted and treated for the invasive cancer of the uterine cervix since July, 1962 till June, 1966 were studied about the clinical therapeutic effects after the irradiation therapy. Four cases with radical operation only and 10 cases with chemotherapy were excluded in this study. The 167 cases were divided into group Ⅰ(119 cases) in which subgroup A treated with Cs137 therapy only and subgroup B with Ra and Cs137 therapy were include, and group Ⅱ(48 cases) in which subgroup C(46 cases) with Cs137 therapy after radical operation and subgroup D(2 cases) with radical operation after the irradiation therapy were included. The following results were obtained; 1. The local lesions of the cervix were improved in about 80 per cent of cases. And the effect was better in subgroup B than in subgroup A. 2. The size of induration from the parametrial invasion was also decreased in about 70 per cent of cases. 3. Incidence of metastasis to the pelvic lymph nodes was 14.3 per cent in 28 cases of stage Ⅰ and 38.8 per cent in 18 cases of stage Ⅱ. 4. Recurrences of the cervical cancer were detected in 23 cases, mostly within one year after radiation therapy. Most prevalent sites were the vaginal wall (16 cases) and pelvic cavity (12 cases). Eleven cases from them expired within one year and twelve cases were lost. 5. As radiation sickness, nausea, general wekness, anorexia, and heakache were most common. And they were most severe in 10th to 15th day after beginning of radiation therapy and then gradually subsided, 6. Erythema and/or dark pigmentation of the skin were common, but excoriation (5.4%), bulla(3.2%), and ulceration(3.2%) were rare 7. Other common complications during radiation therapy were disorders of the rectum (22 cases) and bladder disturbances (11 cases). 8. Survival rate: (1) In group I: Two years after completion of radiation therapy, 70 cases (46.2%) from 149 cases were lost. Three years after completion of radiation therapy, 65 cases (58.6%) from 111 cases were lost. And their survival rates were uncertain. (2) In subgroup C (with Cs137 therapy after radical operation): Two years survival rate in 44 cases, two years after completion of radiation therapy (7 case were lost), was 84.6 per cent in the first stage and 55.6 per cent in the second stage. Three years survival rate in 33 cases, three years after completion of radiation therapy (10 cases were lost), was 63.2 per cent in the first stage and 50.0 per cent in the second stage.

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