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RISS 인기검색어
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- 저자 : 오강열(Kang Yeal Oh) (검색결과 2 건)
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오강열(Kang Yeal Oh),강성귀(Sung Kyew Kang) 대한내과학회 1987 대한내과학회지 Vol.32 No.4
N/A This study was undertaken to investigate whether cell-mediated immunity are affected by renal diseases. Thirty six patients with lipoid nephrosis and chronic proliferative glomerulonephritis, and 16 controlled subjects were studied by summation of delayed-cutaneous hypersensitivity response to 8 test antigens such as Tetamas, Diphtheria, Group C-streptococcus, Tuberculin, Glycerim, Candida albicans, Tricophyton mentaprophytes and protes mirabilis. The total average diameter of all positive reaction in controlled subjects was 15.34±2.03 mm. Of the 16 subjects, negatvie reaction was observed in 3 (18.8%). In patients with lipoid nephrosis, during relapsing phase the total average diameter of all positive reactions was 5.38±2.48 mm. being significantly lower than that of normal subjects. Negative reaction was observed in 9 of 10 patients (90%). The total average diameter of all positive reactions in patients with lipoid nephrosis in the remission phase was 13.09±1.64 mm showing no significant difference in total average diameters between control and remission phase group. Negative reaction was observed in 1 of 9 patients (11.1%). In chronic proliferative glomerulonephritis patients with the nephrotic syndrome, the total average diameter was 10.25±2.20 mm, showing no significant difference with control group, Negative reaction was observed in 3 of 10 patients (30%). The total average diameters of all positive reactions in patients with chronic proliferative glomrulonephritis without nephrotic syndrome was 12. 93±3.48 mm, showing non significant difference in total average diameters between control and patients group. Negative reaction was observed in 2 of 7 patients (28.56%) This study suggests lipoid nephrosis impairs cell mediated immunity, and the impairement of delayed hypersensitivity reaction seems to be related to clinical stages of nephrosis.
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폐결핵환자에서 혈청 Angiotensin-Converting-Enzyme(ACE) 활성도의 변동에 관한 연구
최은영,이양근,유관희,안관용,오강열,박성희 대한내과학회 1986 대한내과학회지 Vol.30 No.1
Angiotensin converting enzyme which is thought to be originated from the epitheloid cells with area of series phagocytosis reported to be inreasced in sarcoidosis, Gaucher`s disease, chronic renal failure, diabetes mellitus and leprosy, The serum ACE activity was assayed spectrophotometrically in 28 pulmonary tuberculosis patients and 13 bronchial asthma patients to investigate ACE activity can be used as an index of tuberculosis activity. The results were as follows: 1) The serum ACE level was higher in patients with active pulmonary tuberculosis (3.4348±3.2079) than in normal control group(1.4026±2.0034) (P0.05). 2) On cheat roentgenographic findings, the serum ACE level was higher in patients of active minimal pulmonary tubereulosis than those of the moderate advanced pulmonary tuberculosis. 3) Forced vital capacity showed significantly strong negative correlation with the serum ACE level(r=-0.4133) while no significant correlation was found between serum ACE level and other pulmonary diseases. It can beuggested that activity of serum ACE is useful parameter to indicate activity E. progress of pulmonary tuberculosis.
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