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RISS 인기검색어
- 검색키워드
- 저자 : 여운철 ( Un Chul Yeo ) (검색결과 5 건)
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여운철,조광현,이유신,허대석,이승철 ( Un Cheol Yeo,Kwang Hyun Cho,Yoo Shin Lee,Dae Seog Heo,Seung Chul Lee ) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.5
A Case of Erythema Multiforme A ssociated with Malignant Lymphoma Un Cheol Yeo, M.D., Kwang Hyun Cho, M.D., Yoo Shin Lee, M.D., Dae Seog Heo*, M.D., Seoung Chul Lee**, M.D Department of Dermatology and Internal Medicine*, College of Medicine, Seoul National University, Seoul, Korea, Department of Dermatology**, College of Medicine, Inha University, Kyung Gi Do, Korea We report a case of erythema multiforme associated with malignant lymphoma. Fifty-six-year-old male patient visited our clinic complaining generalized skin lesions which were compatible with erythema multiforme clinically and histopathologically. The skin lesions were treatment-resistant, recurrent and persistent for 3 years. In consideration of old age, atypical features of erythema multiforme and no other demonstrable etiology of erythema multiforme, we studied for internal malignancy. Malignant lymphoma at the duodenum was revealed by UGI series, abdominal CT, and endoscopic biopsy. After chemotherapy, the tumor mass and active skin lesions were cleared simultaneously. Erythema multiforme may be regarded as one of the paraneoplastic syndromes.
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김병수,이승철,박경찬,권태은,유재학,유희준,조광열,고우석,안종성,임정구,여운철 대한피부과학회 1998 대한피부과학회지 Vol.36 No.6
Background : Vitiligo is an acquired depigmentary disorder of the skin and hair. The etiology is unknown, however an autoimmune hypothesis is favored. Objective : We performed this study to develop a better understanding of the clinical features of vitiligo patients. Method : We evaluated clinical manifestations of 1203 vitiligo patients(556 males and 647 females). Results and Conclusions : 1. The mean age of onset and that of the first visits made by patients were 22.9±18 and 27.9±19 years, respectively. 2. The face(37.4%) was the most common site of initial involvement. In decreasing order of frequency, the common sites of involvement were the face and neck(65.9%), thorax and abdomen(42.9%), upper extremities(42.3%). 44.5% of the cases had the vulgaris type, 26.1% the focal type, and 21.1% the segmental type. During the three months before a visit, 44% of patients experienced progression of disease. Within one year, about 75% of patients reported that the disease had progressed. 3. Precipitating or aggravating factors such as trauma(13.1%), psychological stress(9.2%), sun light (2.8%) and pregnancy(2.5%), were found in 30.9% of patients. Thyroid disease was the most common associated disease.
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김병수,이승철,은희철,유재학,정승용,이일수,여운철,김영걸,고우석,김계정,최호철,이시원 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.5
Background: It is a trend that the average life span is prolonged in proportion to the advance of socio-economy and medical science. Consequently, the number of elderly patients with skin diseases is increasing. Objective: This study was performed to see the change of patterns of skin diseases in elderly patients. Methods: One thousand four hundred and twenty elderly patients, over the age of 65, who visited the departments of dermatology and in five hospitals, from January 1, 1997 to December 31, 1997 were selected. We surveyed the frequeney of skin disease by types and the distributions by month, season and age. Results: The results were as follows; 1. The frequent skin diseases were herpes zoster and postherpetic neuralgia (12.3%), fungal infection (11.3%), pruritus (9.2%), contact dermatitis (6.8%), and seborrheic dermatitis (5.7%). 2. The most frequent was herpes zoster and postherpetic neuralgia in January, February, March, April, June, August and October, in January, July, September and December, fungal infection; in May, contact dermatitis; in November, pruritus. 3. The most frequent skin desease was herpes zoster and postherpetic nueralgia in spring, summer and winter; in autumn, fungal infection. 4. The most frequent skin disease for the 65-74 aged-group was herpes zoster and postherpetic neuralgia; for the over 85 aged group, herpes zoster and postherpetic neuralgia. Conclusion: The results showed that, in contrast to previous studies, herpes zoster and postherpetic neuralgia increased in elderly patients. These findings may be helpful for the government and medical centers to plan and establish a management system on the skin diseases of elderly patients.
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자외선 B 조사에 의한 사람 각질형성세포주 HaCaT 세포의 Interleukin - 1α 생산에 미치는 1 , 25 - Dihydroxyvitamin D3 의 영향
성환태,최지호,성경제,임연순,지두현,장경애,여운철 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.2
Background: Keratinocyte-derived interleukin-1 (IL-1) αis one of the key cytokines in initiation of cutaneous inflammation. Release of IL-1 αfrom human keratinocytes may be induced by proinflammatory stimuli including ultraviolet B (UVB) irradiation, and subsequently, keratinocyte-derived IL-1 αmay exert numerous paracrine and autocrine effects. 1,25-dihydroxyvitamin D_3(1,25(OH)_2D_3) is involved in the regulation of keratinocyte proliferation and differentiation and is also recognized to have immunoregulatory properties such as an antiinflammatory effect. Objective: The purpose of this study was to investigate the in vitro effects of 1,25-(OH)_2D_3 on the production of IL-1 αby UVB irradiation in cultured human keratinocyte cell line HaCaT cells. Results: are summerized as follows; 1. The vialility of cultured HaCaT cells measured by MTS assay at 24 hours after UVB irradiation was significantly reduced at the doses of above 100 mJ/㎠ of UVB(p$lt;0.05). 2. The secretion of IL-1 αby HaCaT cells was significantly increased at the doses of above 30 mJ/㎠ of UVB(p$lt;0.05). UVB irradiation could not influence cm the secretion of IL-1 αby HaCaT cells. 3. At the concentrations of 10-8M and 10-6M of 1,25(OH)_2D_3, the production of IL-1 α by HaCaT cells(48 hours after 100 mJ/㎠ UVB irradiation) was significantly inhibited in tth culture supernatants and cell lysates(p$lt;0.05). Conclusion: UVB irradiation increased the production of IL-1 αby HaCaT cells and this stimulatory effect on the production of IL-1 αinduced by UVB irradiation was suppressed by 1,25-(OH)_2D_3. Calcipotriol(MC-903) had similar suppressive effect on the production of IL-1 αinduced by UVB irradiation in HaCaT cells to that of 1,25(OH)_2D_3
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