활로 4징증에서 폐동맥의 상태와 수술성적과의 관계

안재호,서경필,An, Jae-Ho,Seo, Gyeong-Pil 대한흉부심장혈관외과학회 1984 Journal of Chest Surgery (J Chest Surg) Vol.17 No.4

In Tetralogy of Fallot, the most common congenital cyanotic heart disease, the mortality is decreasing continuously with adequate type and timing of operation. At S.N.U.H., 195 patients were operated from January 1982 to December 1983 and 176 patients among them were analysed in the view of pre-operative pulmonary arterial condition measured by cardiac cineangiogram. The most common associated anomaly was PFO and ASD and they did not affect the postoperative course and mortality. The overall mortality rate was 8.5% in 1982 and 6.8% in 1983 but under 2 years of age, the mortality rate was relatively high as 25% in 1982 and 16.7% in 1983, and when transannular patch widening of Right Ventricular Outflow Tract was used, the mortality rate was 12.5% in 1982 and 27.3% in 1983. Preoperative angiographic measurements of the pulmonary arterial status for prediction of the ratio between the Left Ventricular and Right Ventricular peak systolic pressure were calculated retrospectively according to the Blackstones formula, and the predicted value of PRV/LV greater than 0.6 carried apparently high complication and mortality rate as 16.6% M.R. in 1982 and 11.1 % in 1983. Among postoperative complications, c-RBBB occurred most frequently about 50% but did not influenced to mortality, Low Cardiac Output Syndrome was developed in about 40%. If we select the patient who should have the staged operation including shunt operation and choose the type of RVOT relief, we expect the improvement of postoperative clinical results.

토끼 단일 심실근 세포에서 cyclic GMP의 $Ca^{2+}$ 전류 조절기전에 관한 연구

안재호,서경필,엄융의,An, Jae-Ho,Seo, Gyeong-Pil,Eom, Yung-Ui 대한흉부심장혈관외과학회 1992 Journal of Chest Surgery (J Chest Surg) Vol.25 No.4

In order to investigate the effect of intracellular cyclic GMP on the calcium channel, whole cell patch clamp technique with internal perfusion method was used in the single ventricular myocytes of the rabbit. Cyclic GMP, cGMP analogues, cAMP, isopernaline and forskolin were perfused into cells and their effects on the calcium current were analysed by applying depolarizing step pulse of 10 mV in amplitude for 200 msec from holding potential of -40 mV. Calcium currents usually activated from -30 mV and then reached a peak at +10 mV. Amplitude of the calcium current was standardized with membrane capacitance, 50 pF. Peak amplitude at +10 mV in control was -0.15 nA/50pF. When 100 mM cAMP was applied from the pipette, peak amplitude of calcium current increased to -0.32 nA and addition of 1 mM isoprenaline further increased its amplitude. In the presence of cGMP it alone also produced an increase of the calcium current to -0.52 nA/50pF and addition of isoprenaline or forskolin increased its magnitude to -[0.55~0.95] nA/50pF. Simultaneous application of cGMP and cAMP increased the calcium current to -0.67 nA/50pF. Among the cGMP analogues, 8-Br-cGMP was the most potent stimulant for the calcium current activation. From the above results it could be concluded tlat cGMP increases the calcium current not through cAMP dependent protein kinase nor cAMP dependent phosphodiesterase pathway, but through independent phosphorylation pathway, possibly cGMP dependent protein kinase pathway.

소의 심낭을 이용한 이종이식 보철편의 개발 (I)고정액의 농도와 장력

안재호,김용진,An, Jae-Ho,Kim, Yong-Jin 대한흉부심장혈관외과학회 1989 Journal of Chest Surgery (J Chest Surg) Vol.22 No.3

Glutaraldehyde is known as an ideal preservatives for pericardial heterograft, and many laboratories used this chemicals for preparing tissue valves, pericardial patches and MVOP [monocusp ventricular outflow patch] so we tried to find out the appropriate concentration and ingredients of the Glutaraldehyde for the preparing bovine pericardium. We selected 50 calves, aged about 2 years, and procured their pericardia. These were divided 6 groups such as fresh group, treated with only antibiotics, treated with Glutaraldehyde 0,5%, 0.625 %, 0.75 %, and 0.875 %, and our experiments included microbial culture test, tensile strength measurement and microscopic examination. On microbial culture, there were no growth on 1 week and 4 weeks after preparation with all kind of Glutaraldehyde, but on 4 weeks after only antibiotics treatment [Penicillin, Streptomycin, Kanamycin, Amphotericin -B] E.coli and candida albicans were observed. On tensile strength test, 0.625 % and 0.75 % Glutaraldehyde were revealed as the best preservatives for bovine pericardium and compared to other commercial products they kept more desirable tensile strength. On light and electron microscopic examinations, Glutaraldehyde treated pericardia had much regular and compact collagen fibers and preserved more normal structures, but there were no difference between the different concentration of the Glutaraldehyde. We concluded that 0.625% and 0.75 % Glutaraldehyde were the best concentration for preservation of bovine pericardium in our experiment.

심에코를 이용한 승모판막이식환자의 예후결정요소에 관한 임상적 고찰

안재호,서경필,An, Jae-Ho,Seo, Gyeong-Pil 대한흉부심장혈관외과학회 1983 Journal of Chest Surgery (J Chest Surg) Vol.16 No.1

A hundred and eleven patients of mitral valvular heart disease, who were operated at Seoul National University Hospital, were analysed with echocardiogram before and after operation during the period from November 1979 to February 1982. Twenty-eight patients had mitral stenosis and eighty-three mitral regurgitation. In patients with mitral stenosis, right ventricular end-diastolic volume was in normal range at preoperative and postoperative period. But the left ventricular end-systolic volume was slightly increased preoperatively to 35.4mm and decreased to 33.5mm on immediate postoperative period and 32.5mm after a year later. The left ventricular end-diastolic volume was 50.5mm preoperatively and fell to 46.8mm postoperatively. Ejection fraction was normal preoperatively and postoperatively without changes. Left atrial size fell significantly from 50ram to 37.6mm at the time of late follow-up study. With mitral regurgitation, right ventricular end-diastolic volume was also normal preoperatively and postoperatively. The left ventricular end-systolic volume was increased to 41.9mm and decreased to 31.6mm postoperatively with statistic significance. Left ventricular end-diastolic volume fell from 58.5mm to 45.7mm significantly at the time of late follow-up period. Ejection fraction was also within normal range and had no changes postoperatively. Left atrial size fell from 54.8mm to 45.5mm on a year later [ p value less than 0.01 ]. When atrial fibrillation, the left atrial dimension was increased as 54.9mm compared with 46.8mm of no atrial fibrillation patients.

청색심기형 교정술후 혼합정맥혈 산소분압과 심근상태 및 혈류역학치와의 상관관계 분석

안재호,김용진,An, Jae-Ho,Kim, Yong-Jin 대한흉부심장혈관외과학회 1989 Journal of Chest Surgery (J Chest Surg) Vol.22 No.2

We utilized pulmonary artery pressure monitoring system in risky patients for preventing the postoperative pulmonary hypertensive crisis and for sampling the mixed venous blood. And this mixed venous blood oxygen saturation [MVSO2] or partial pressure [MVPO2]tells us many meaningful patients state. We selected 59 cyanotic congenital heart diseased patients, who were operated in our hospital from Nov. 1987 to Oct. 1988, in the Department of Thoracic and Cardiovascular Surgery, Seoul National University Children\ulcorner Hospital, who had pulmonary artery pressure monitoring catheter and who made us know their mixed venous oxygen condition. We found that there was no close relationship between MVPO2 and Cardiac Index [C.I.] during early postoperative period, but on the first and second day after operation the correlation coefficient was increased as r=0.35[p=0.008], r=0.78[p=0.0001]. So we concluded that the correlation between MVPO2 and C.I. was more reliable with time going as hemodynamic stabilization. And we experienced no survivors whose MVPO2 was under 20 torr, but that was not the only factor for death. From these results, we conclude that we can consider the MVPO2 [or MVSO2] representing C.I. after stabilized postoperative condition of the open heart surgery patients, but during early postoperative period, in addition to this MVPO2, we should do also apply other parameter such as urine output, arterial blood pressure, left atrial pressure and pulmonary arterial pressure for exact estimation of the patients status.

양성 식도 협착

안재호,김주현,An, Jae-Ho,Kim, Ju-Hyeon 대한흉부심장혈관외과학회 1988 Journal of Chest Surgery (J Chest Surg) Vol.21 No.6

297 cases of military personnel and 7 cases of civilian were operated in K.A.F.C.H. from January 1982 to October 1988 due to cardiovascular disease, which consist of 202 cases [66.4%] of vascular disease, 91 cases [29.9%] of cardiac disease, and 11 cases [3.6%] of pericardial disease. Mean age was 25.8*7.2[2S.D.] year of age and nearly all patients were male except 4 cases of female patient in civilian. Of the 253 cases [83.2%] of acquired disease, vascular diseases were 149 cases [583%], traumatic cardiovascular 54 [21.3%], cardiac 40 [15.8%], and pericardial 10 [4.0%]. Of the 51 cases [16.8%] of congenital diseases, cardiac anomalies were 48 cases [94.1%], vascular 2 [3.9%] and pericardial 1 [2.0%]. Open heart surgery was done in 83 cases of cardiac disease, which consists of 39 cases [46.9%] of valvular heart disease, 22 cases [26.59o] of ASD, 14 cases [16.9%] of VSD, 2 cases [2.4%] of partial ECD, and so on. Of the 6 cases [2.0%] of over-all mortality, operative death in open heart surgery was 4 cases[4.8%].

류마치스성 심장질환 환자에서 대동맥판막치환

안재호,이영균,An, Jae-Ho,Lee, Yeong-Gyun 대한흉부심장혈관외과학회 1984 Journal of Chest Surgery (J Chest Surg) Vol.17 No.3

77 cases of Aortic Valve Replacement, which were composed of 64 rheumatic valvular heart disease and 13 combined congenital heart disease, were operated at Seoul National University Hospital for Aortic valvular disease during the period from June 1968 to December 1983. Among these 64 rheumatic aortic valvular heart disease cases, 8 patients were expired during and immediate after operation and overall mortality rate was 12.5%. For more precise remarks, these patients were divided into two periodic groups, 1st period [from 1968 to 1976] and 2nd [from 1977 to 1983] when annual open heart surgery were over 100 cases, and in 1st period three of four patients were died and in 2nd period five of sixty patients were died and its mortality rate was 8.3%. There were 12 cases of postoperative complication, which were 3 cases of remaining other valvular heart disease required MVR, 2 paravalvular leaks [one of them got Redo AVR], 4 thromboembolism or problem of anticoagulant therapy, 2 late death due to SBE with replaced valve failure and one functional AS with small sized valve. Operative death was affected by pump-time and aortic cross-clamping time, heart size, Ejection Fraction, LVEDP and symptom duration, and other many factors may influence the survival rate. Improved operative technique and myocardial protection and meticulous evaluation of the preoperative patient status will make the AVR safer.

中國 双砣子3期土器의 基礎的編年

安在晧(Ahn Jae ho) 한국상고사학회 2015 한국상고사학보 Vol.90 No.-

双砣子文化는 중국 요동반도 청동기시대의 개시기이면서, 한반도 청동기시대의 형성에 결정적인 영향을 미쳤다. 본고는 주거지가 많이 검출된 쌍타자3기문화의 편년을 위하여 작성되었다. 대상유적은 공반유물이 많고 보고가 충실한 双砣子遺蹟과 大嘴子遺蹟에 국한하였다. 편년을 위하여 우선 壺와 甕을 규격과 형태를 통하여 21개의 기종으로 나누었다. 연구방법은 型式學的屬性分析法을 사용하였으며, 그러기 위해서는 유물의 수량이 다소 존재하는 기종 8개만을 대상으로 삼을 수밖에 없었다. 분류는 주로 구연 동체 대각 등의 형태를 속성으로 삼았으며, 분석을 통하여 시간적 속성을 찾아내었다. 이렇게 각 기종마다 상대연대가 만들어졌는데, 이것을 다시 順序配곢補充法에 따라 종합하여서 총19군(단계) 7개의 분기로 편년되었다. 그 결과는 1단계=쌍타자1기, 2-3단계=쌍타자2기, 4-5단계=쌍타자3a기, 6-9단계=쌍타자3b기, 10-12단계=쌍타자3c기, 13-15단계=쌍타자3d기, 16-19단계=3e기로 설정하였다. 문양은 區劃文과 主文으로 나누어 고찰하였는데, 시간성을 가지는 것은 구획문이었고 단순화의 과정으로 변천하였다. 쌍타자문화에서 한반도 청동기시대와 관련있는 돌대문은 쌍타자2기에 악석문화의 영향으로 나타난 것임을 다시 확인하였다. 주거지는 중첩된 경우가 있는데, 주거지 사이의 층서관계도 본 편년안과 정합성을 가지는 것을 확인하였다. Shuangtuozi culture has a significance not only as the beginning of the Bronze Age in Liaotung Peninsula but as what had a decisive influence on the formation of the Bronze Age in Korea Peninsula. The aim of this paper is to make a chronology of the third period of Shuangtuozi culture, many dwelling sites of which were already excavated. The artifacts of the study were restricted to Shuangtuozi and Dazuizi sites and the pots and urns from these sites were sorted into 21 categories based on their size and form. In order to apply Typological Attributes Analysis methods, 9 categories with an enough number of samples were chosen out of these 21 categories. Through the analysis of the typology taking the forms of earthenwares' rim, body and leg as its attributes, certain temporal attributes of the artifacts were identified, thus, the relative dates of each pot and urn could be specified. As a result of the application of Supplement Seriation methods to these relative dates, the chronology with total 19 stages and 7 periods was produced. The first stage was assigned to “the first period” of Shuangtuozi culture, the 2nd-3rd stage were to “the second period,” the 4th-19th stage were to “the third period,” of Shuangtuozi. The decoration was studied in terms of division patterns and main patterns(主文), and what showed temporal attributes were the division patterns, which had transformed into simpler ones.

IPCC 방법을 이용한 시화 · 반월 산업단지의 온실가스 배출량 산정 연구

안재호(An, Jae-Ho) 한국생태환경건축학회 2011 한국생태환경건축학회 논문집 Vol.11 No.2

호굉(胡宏)의 성체심용설(性體心用說) 천석(淺析)

안재호 ( Ahn Jae-ho ) 한국동서철학회 2017 동서철학연구 Vol.0 No.83

호굉의 사상에 있어 性 개념은 물론 중요하다. 그러나 그것만이 근본은 아니며 더구나 성 자체의 공부를 말하지 않았기 때문에, 그의 유학사상을 “性本論”이나 “性學”이라고 규정하는 것은 적절하지 않은 것 같다. 오히려 호굉의 선명한 주장, 즉 性體心用과 에 따른 盡心成性 등의 명제에 근거해서 기존과는 다른 형태의 `心性學`이라고 부르는 것이 더욱 타당할 것이다. 호굉의 이런 `심성학` 체계는 북송 유학자들이 강조한 본체, 즉 중용 역전에 근거한 우주본체를 선진유학, 특히 맹자의 논리 형식인 卽心言性을 계승한 것으로 유학사에 상당한 공헌이 있다고 평가할 수 있다. In Hu Hong`s Confucian thoughts, Xing(性) is an important notion. However, I think it is not proper interpretation for his philosophy to call it as Xingbenlun(性本 論) or Xingxue(性學), because he has never suggested cultivation to Xing directly. I argue that Hu Hong`s theory of Xing should be considered as different type of Xinxingxue(心性學) with neo-confucian works, because of his core propositions like Xingtixinyong(性體心用), Jinxinchengxing(盡心成性). This new structure of Xinxingxue has succeeded the notion in Benti(本體) which is based on the Doctrine of Mean, Commentary on the Book of Changes through Jixinyanxing(卽心言性) which is logical form of Mencius. Therefore, the evaluation of this study is that Hu Hong`s theory has made a big contribution to the history of confucianism.