「 성경 」에 실린 별들의 동정 (同定)

안상현,박창범,유경로 ( Sang Hyun Ahn,Chang Bom Park,Kyung Loh Yu ) 한국과학사학회 1996 한국과학사학회지 Vol.18 No.1

천년 전의 별똥비

안상현,배현진,조혜전,정성욱,AHN SANG-HYEON,BAE HYUN JIN,CHO HYE JEON,JUNG SUNG-WOOK 한국천문학회 2002 天文學論叢 Vol.17 No.1

별똥에는 분산 별똥(sporadic meteors)과 별똥비(meteor shower)에 속하는 별똥이 있다. 우리는 $\ulcorner$고려사$\lrcorner$ $\ulcorner$천문지$\lrcorner$에 적혀 있는 별똥 기록을 조사하여 10세기에서 14세기까지 지구 공전 궤도 상의 별찌(meteoroids)의 분포에 대해서 연구하였다 먼저 $\ulcorner$고려사$\lrcorner$ 에 나오는 별똥 기록의 간지날짜를 점검하여 교정하고 간추려서 자료를 만들었다. 별똥이 나타난 날짜를 조사하여 고려 시대의 별똥별의 특징을 살펴보았다. 고려 시대 별똥 기록은 각 시기에 유행한 철학 사조의 영향과 전쟁과 내란 등의 영향으로 기록 수가 변하는 것으로 추정하였다. 그러나 평소에 떨어지는 분산 별똥들의 계절적 개수 변화는 매우 자연스러웠다. 우리는 일년 중 특정한 날짜에 별똥별이 많이 떨어지는 시기가 몇 개 있음을 발견하였다. 우리는 이것을 별똥비로 보고, 한국$\cdot$일본$\cdot$중국$\cdot$아랍$\cdot$유럽의 역사 기록에 나오는 별똥 소나기 기록을 모두 조사한 다음, 이것을 $\ulcorner$고려사$\lrcorner$의 별똥 기록에서 구한 별똥비와 비교하였다. 우리는 뚜렷한 별똥비 셋과 약한 별똥비 서넛을 확인할 수 있었다. 뚜렷한 세 별똥비는 사자자리 별똥비, 페르세우스 별똥비, 핼리혜성이 남기는 두 별똥비 등의 요즘 별똥비와 각각 일치함을 알아냈다 또한 나머지 약한 별똥비들도 오늘날 관측되고 있는 약한 별똥비와 대체적으로 일치함을 보았다. 결론적으로 고려시대의 별똥비의 활동성은 오늘날의 그것과 크게 다르지 않았다. 이것은 오늘날 활발한 별똥비들의 수명의 하한을 주는 결과이다. 이러한 연구를 통해 별똥 관측에 있어서 우리나라 옛 사람들이 남긴 관측 기록은 실제 자연의 모습을 그대로 읽어낼 수 있을 정도로 꾸준하고 정밀하고 정직한 것이었음을 알 수 있었다. 또한 그러한 좋은 유산을 현대 천문학에 유용한 연구 자료로서 활용할 수 있었다. The spatial distribution of meteoroids or cometary debris along the orbit of the Earth is investigated by analyzing the meteoric records in the Chronicle of the Koryo dynasty (918-1392) which is called Koryosa. Sporadic meteors in this period show the seasonal variation in number, which is similar to the current meteors. We also found that there are a few spikes showing large accumulation of records around the same dates. We regard these spikes as meteor showers in the Koryo period. We compared the dates of meteor showers with those compiled from the historical records around the world including Korea, Japan, China, Arab, and European countries. We discovered three prominent showers and four weak showers. The prominent ones are the Leonids, the Perseids, and the Aquarids and the Orionids pair. The last pair is the remnants of Halley's comet. The astronomical records written in the history book of the Koryo dynasty are turned out to be accurate and written in a steady manner. We can also see that those records can be useful to contribute the development of modern astronomy and astrophysics.

두시 하태독법이 시행된 비만 생쥐에서 Th2 분화조절을 통한 알러지성 비염 유발 감소 효과

안상현,김기봉,Ahn, Sang Hyun,Kim, Ki Bong 대한한방소아과학회 2018 대한한방소아과학회지 Vol.32 No.2

Objectives This study investigated the effects of Hataedock treatment with Douchi on induction of allergic rhinitis in obese induced NC/Nga mice. Methods NC/Nga mice were divided into control group (Ctrl), allergic rhinitis induced obese mice group (ARE), and allergic rhinitis induced obese mice group with Douchi Hataedock treatment (FGT). The 3-week-old mice of the FGT group were given one 10 mg/kg dose of Douchi Hataedock extract and sensitized with allergic antigens at weeks 4, 5, and 6. After 1 week of final sensitization, allergic rhinitis was induced primarily in mice nasal cavities for five days. After one week of the completion with the first induction, the second induction was introduced by the same method. After 1 week, few samples of the nasal mucosal tissues of each group were prepared. The factor of Th2 differentiation and inflammation control such that IL-4, STAT6, CD40, $Fc{\varepsilon}RI$, substance P, MMP-9, $NF-{\kappa}B$ p65, p-IkB, iNOS and COX-2 were observed by immunohistochemistry. Also, the difference in nasal mucosal injury was observed by histochemical method (PAS staining). Results The FGT group showed that reduced IL-4 production, STAT6 expression and CD40 expression by regulating excessive Th2 differentiation. Also, production of substance P and MMP-9 and activity of $Fc{\varepsilon}RI$ in mast cells were decreased. Inhibition of $NF-{\kappa}B$ p65 activity was induced by inhibition of p-IkB, and the production of inflammatory enzymes iNOS and COX-2 were decreased. In addition, the damage of intramural respiratory epithelium was low and excessive mucin secretion in goblet cells was low. Conclusions This study confirmed the possibility of controlling the allergic rhinitis in obese children who are expected to have an overactive inflammation.

두시 하태독법의 IL-4 활성 조절이 D. farinae 유도 아토피유사피부염 발병 조절에 미치는 효과

안상현,김재규,천진홍,김기봉,Ahn, Sang Hyun,Kim, Jae Kyu,Cheon, Jin Hong,Kim, Ki Bong 대한한방소아과학회 2017 대한한방소아과학회지 Vol.31 No.1

Objectives Hataedock method is a Korean medical therapy which removes fetal toxin by orally administering herbal decoction to neonates. This study was to observe skin damage and anti-inflammatory effect via regulating IL-4 activity in NC/Nga mice which were induced atopic dermatitis (AD)-like skin lesion by Dermatophagoides (D.) farinae after applying Douchi Hataedock method. Methods NC/Nga mice with 3 weeks of gestational age were used. Each 10 mice were allocated to the control group (Ctrl), the AD-induced group (AE), and the group which induced AD after administering Douchi extract (GT). After 4 weeks from administering Douchi extract to the mice, the primary AD was induced by applying D. farinae extract 6 times per week for 3 weeks and then the secondary AD was induced by the same method after 1 week from the primary AD induction. To identify the skin damage and anti-inflammatory effect, we observed LxR, IL-4, Fc ${\varepsilon}$ receptor, substance P, and $NF-{\kappa}B$. Results The GT group showed alleviation of skin injury and decrease in capillary angiogenesis. Stratum corneum damage, epithelial cell hyperplasia, lymphocyte infiltration, and capillary distribution relatively decreased in the GT group. LxR-positive reaction in the GT group were increased by 53% than that of the AE group. IL-4 production, $Fc{\varepsilon}$ receptor activity, and substance P-positive reaction in the GT group were decreased by 82%, 42%, and 82% respectively compare to those of the AE group. $NF-{\kappa}B$-positive reaction in the GT group were decreased by 15% compare to that of the AE group. Conclusions Hataedock method with Douchi extract alleviated AD via reducing inflammatory cytokines secreted at the early stage of AD. Thus, Douchi Hataedock method has a beneficial effect for the prevention and treatment of AD.

백호탕 추출물의 지방장벽 손상 개선을 통한 상피 내 Th2 분화 조절 효과

안상현,김기봉,정아람,Ahn, Sang Hyun,Kim, Ki Bong,Jeong, Aram 대한한방소아과학회 2021 대한한방소아과학회지 Vol.35 No.4

Objectives The purpose of this study is to confirm the regulate effect of T helper (Th) 2 differentiation that Baekho-tang extract may produce to improves skin lipid barrier damages. Methods Four-weeks-old NC/Nga mice were divided into four groups: control group (Ctrl, n=10), lipid barrier eliminated group (LBE, n=10), Dexamethasone treatment after lipid barrier elimination group (DxT, n=10), and Baekho-tang extract treatment group after lipid barrier elimination group (BHTT, n=10). Baeko-tang extract was administered for 3 days after removal of the skin fat barrier in BHTT group. Then, we identified changes in external symptoms of the skin, factors affecting skin barrier such as potential of hydrogen (pH), filaggrin (FLG), transepidermal water loss (TEWL) and Th2 differentiation factors like Interleukin (IL)-4, Kallikrein Related Peptidase 7 (KLK7) and protease activated receptor 2 (PAR-2) through our immunohistochemistry. Results After lipid barrier elimination, the reduction of morphological skin inflammations was less in BHTT group than in LBE group and DxT group. Also, pH and TEWL were significantly decreased with BHTT group. However, FLG was significantly increased in BHTT group compared to LBE, DxT, and Ctrl group. All kinds of Th2 differentiation factors (IL-4, KLK7 and PAR-2) were also decreased in BHTT compared to the LBE and DxT. Conclusions As a result of this study, BHT administration decreased pH, TEWL, and increased FLG, thus participating in recovering damaged skin barrier. Since Th2 differentiation factors were decreased as well, BHT's regulatory effect in sequential immune reactions may be a possible explanation of how it enhances recovery of the damaged lipid barrier.

포스터 발표 - 무기재료분과 / 전기화학분과 / 촉매분과 : 인산형 연료전지의 가스확산전극의 구조개선과 전기화학적 특성평가

안상현,심재철,유덕영,김인,이주성 ( Sang Hyun Ahn,Jae Cheol Shim,Duck Young Yoo,In Kim,Ju Seong Lee ) 한국공업화학회 1997 한국공업화학회 연구논문 초록집 Vol.1990 No.3

황련추출물-ceramide 복합물의 지방장벽 형성 조절을 통한 상피 염증 완화 효과

안상현,김기봉,Ahn, Sang Hyun,Kim, Ki Bong 대한한방소아과학회 2021 대한한방소아과학회지 Vol.35 No.3

Objective The purpose of this study was to confirm the effectiveness of coptidis rhizoma extract-ceramide complex on skin barrier, transepidermal water loss (TEWL) and pH reduction, and inflammation of the skin. Methods Coptidis rhizoma extract-ceramide complex was applied in 6-week-old Balb/C mice after dermatitis was induced. To confirm the skin condition changes, TEWL and pH were observed, and filaggrin in the stratum corneum of the skin was observed. Kallikrein-related peptidase (KLK) 7, Protease activated receptor (PAR)-2, Thymic stromal lymphopoietin (TSLP), and IL-4 were observed in the stratum corneum to confirm the changes in the inflammatory response. Results Filaggrin positive reaction was increased in the experiment group compared to the control group. TEWL and pH were lower in the experiment group compared to the control group. KLK7, PAR2, TSLP, and IL-4 positive responses were decreased in the experiment group compared to the control group. Conclusions It was confirmed that the coptidis rhizoma extract-ceramide complex can relieve the inflammatory response of atopic dermatitis by restoring the skin lipid barrier damage.

강 슬리브 파단 직선 슬리브의 장력 및 열적 특성 분석 연구

안상현,김병걸,김상수,손홍관,박인표,김성규,Ahn, Sang-Hyun,Kim, Byung-Geol,Kim, Sang-Shu,Sohn, Hong-Kwan,Kim, In-Pyo,Kim, Sung-Kyu 한국전기전자재료학회 2008 전기전자재료학회논문지 Vol.21 No.11

According to previous report, aged sleeves of old transmission line showed several defaulted installation patterns, which was biased or corrosive-fractured of steel sleeve installed cases. These defects can cause serious accidents such as rapid increasing of sag or falling out of overhead conductor from sleeves. Consequently, the defects lead to the major power outage. Corrosion of steel sleeve is a typical defect by aging of sleeves. And it occupied almost 25 percent of investigated aged sleeves. This paper studied thermal properties and tension for ACSR conductor in case of fractured steel sleeve model by corrosion. The temperature distribution within overhead conductor has a specific gradient. Thermal properties of splice connectors(sleeve and clamp) showed normal behavior. However, mechanical properties were worse than normal sleeves. The detailed results were presented in the text.

건설사업관리(CM) 관리인력 규모산정을 위한 사례연구 - 공공공사 건축공사 사례를 중심으로 -

안상현,김진대,Ahn, Sang-Hyun,Kim, Jin-Dae 한국건설관리학회 2013 한국건설관리학회 논문집 Vol.14 No.4

국내 CM현장은 경기침체로 인해 성장이 다소 둔화되고 있지만 최근 공공기관 이전사업 등으로 인해 CM시장은 꾸준한 규모를 보이고 있다. CM제도가 도입된 이래로 다수의 발주기관들이 건설사업관리 역량을 점차 보유하고 있지만 이에 대한 건설사업관리 조직 규모 산정을 위한 노력은 미흡한 실정이다. 본 연구에서는 공공공사 건축공사 10개소 사례를 바탕으로 통계분석과 관리인력당 사업비를 활용하여 건설사업의 관리업무를 수행하는 전체 관리조직의 규모 산정 방법을 도출하였고 Case Study를 통해 활용성을 검토하고자 하였다. 이를 통해 적정 관리인력 규모 산정 및 투입으로 건설사업의 원활한 업무수행과 성공적으로 사업을 수행하는데 기여하고자 하였다. While growth of domestic CM market has slowed down due to economic recession, it recently shows sign of scale as some public agencies are relocating their headquarters. Since the introduction of CM system, a number of client organizations have acquired construction project management capabilities, however, sufficient efforts are not made to estimate the size of construction project management organization. This study drew a method for estimating the size of the organization managing construction project by utilizing statics analysis and project costs per member based on 10 public construction projects and tried to review applicability through case studies. With this study, we would like to make a contribution to achieving smoother work performance and success of the construction project by estimating and allocating proper scale of management workforce.

PKC 활성 조절을 통한 두시 하태독법의 항염증작용이 Mite 항원 유도 아토피유사피부염 발병 조절에 미치는 효과

안상현,김기봉,Ahn, Sang Hyun,Kim, Ki Bong 대한한방소아과학회 2016 대한한방소아과학회지 Vol.30 No.4

Objectives Hataedock (HTD) is an oral Korean herbal medical oral treatment that removes fetal toxic heat and meconium from new born babies. The purpose of this study is to evaluate whether Hataedock treatment of Duchi extracts has anti-inflammation effects in atopic dermatitis-like skin lesions in House Dust Mite-Induced NC/Nga Mice. Methods The mice were divided into 3 groups (n=10 per group) as follows: the control group (Ctrl group), AD-induced group (AE group), AD-induced with HTD treatment group (DT group). 3-week-old NC/Nga mice were introduced to Hataedock treatment, made of Duchi extract. After 4 weeks, House Dust Mite-Induced application was used six times per week for 3 weeks to induce the first atopic dermatitis, and second AD in 7 weeks after. To examine skin injuries and anti-inflammatory effect, PKC, MMP-9, iNOS immunohistochemistry were used. Results The alleviate effect of the skin damage and angiogenesis was observed in DT group. The damage of stratum corneum, hyperplasia, edema, infiltration of lymphocytes and distribution of capillary were decreased in DT group. Also, the study results suggested that Hataedock treatment made of Duchi extracts in DT group remarkably decreased skin damages by 51% (p < 0.001), as well as PKC by 91%, MMP-9 by 48% (p < 0.001), iNOS by 51% (p < 0.001). Conclusions Based on the study results, we observed that Hataedock treatment of Duchi extracts alleviates AD by diminishing various inflammatory cytokines, initial steps of AD development, in the skin lesions. Potential applications for prevention and treatment of atopic dermatitis are expected.