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상기도폐쇄 환자에 있어서 He-O2~혼합가스 흡입 후 류량기량곡선의 반응
심재두,김원동,강홍모,임선희,유지홍 대한내과학회 1986 대한내과학회지 Vol.31 No.3
In order to evaluate the ability of air and He-O2, maximal expiratory flow-volume curves to distinguish upper airway obstruction from peripheral airway obstruction of chronic obstructive pulmonary disease, the increase in expiratory flows at peak, 25, 50 and 75 per cent of forced vital capacity during He-O2 breathing compared to air breathing was determined in 10 normal control, 10 patients with chronic obstructive pulmonary disease and 10 patients with documented upper airway obstruction. 1) There was n significant difference in age and FVC, FEVFEU,/FVC and FEF 25 - 75% between the patients with chronic obstructive pulmonary disease and upper airway obstruction. 2) There was no significant difference in the increase of expiratory flows at 50 and 75 per cent of forced vital capacity between the patients with upper airway obstruction and normal controls. 3) There was significant difference in the in- crease of expiratory flows at 50 and 75 per cant of forced vital capacity between the patients with upper airway obstruction and chronic obstructive pulmonary disease. We conclude that upper airway obstruction can usually be identified by high helium responses and that upper airway obstruction can be identified even in the presence of more peripheral airway obstruction by a normal helium response at 50 and 75 percent of forced vital capacity.