Comparison of Perioperative Blood Loss in Primary Non-cemented Total Hip Arthroplasty for Rapidly Destructive Coxarthrosis and Osteonecrosis of the Femoral Head

송주현,한석구,이경훈,이재민,이기행 대한고관절학회 2015 Hip and Pelvis Vol.27 No.3

Purpose: The purpose of this study is to compare the perioperative blood loss in primary non-cemented total hip arthroplasty (THA) performed for rapidly destructive coxarthrosis (RDC) with the perioperative blood loss in primary non-cemented THA for typical osteonecrosis of the femoral head (ONFH). Materials and Methods: From January 2000 to December 2013, 19 patients were diagnosed with RDC (group 1) and 40 patients were diagnosed typical Ficat stage IV ONFH (group 2), comparison of perioperative blood loss between group 1 and group 2 in primary noncemented THA was done. Patients with preoperative usage of steroid or anticoagulants medication and with hemodynamic abnormal blood test results were excluded. The blood loss was measured up to the fifth post operation day and calculated with formula proposed by Mercuriali, Inghilleri and Nadler. Results: Non-compensated blood loss calculated in milliliters of red blood cells was 362 mL (standard deviation [SD], 187; range, 77-675) in group 1 and 180 mL (SD, 145; range, 53-519) in group 2. Compensated blood loss was 630 mL (SD, 180; range, 380-760) in group 1 and 503 mL (SD, 260; range, 190-1, 505) in group 2. The total blood loss after primary non-cemented THA is greater when surgery is performed for RDC than for ONFH, with the volume of 992 mL (SD, 300; range, 457-1, 434) in group 1 and 683 mL (SD, 360; range, 226-1, 975) in group 2 respectively. Conclusion: Total perioperative blood loss was significantly greater in RDC than in ONFH in primary noncemented THA.

학교 음악교육의 음악 교과 역량 연구

송주현 한국음악교육학회 2015 음악교육연구 Vol.44 No.4

본 연구는 최근 교육과정 개정의 쟁점으로 부각되고 있는 역량 중심 교육과정 동향에 발맞춰 우리나라 학교 음악교육 상황에 적합한 음악 교과 역량의 구조를 개발하는데 목적이 있다. 이를 위해 외국 초·중등학교 음악과 교육과정 문서 분석을 통해 음악 교과 역량 구조 개발 사례를 검토하였다. 이를 기반으로 국내 30여명의 음악교육 전문가를 대상으로 델파이 조사를 실시하여 음악 교과 역량 구조를 도출하고 전문가 협의회를 거쳐 재구성하였다. 연구 결과는 다음과 같다. 첫째, 음악 교과 역량은 ‘수용’, ‘표현’, ‘성찰’로 구성된다. 둘째, 국가수준에서 제시한 교과 공통의 핵심역량과 연계된 음악 교과 역량을 개발하였다.

1960년대 한국 현대소설에 나타난 자살의 윤리학

송주현 영남대학교 민족문화연구소 2014 민족문화논총 Vol.58 No.-

This paper maps and interprets Korean novels in the 1960s in respect of the ‘suicide’ motif. Suicide was an intrinsic literary form that characterized the Korean novel of the 1960s. Suicide provided the writers of the 1960s with a form to create and represent their own worlds and ethics. It represented their deliberate reflections on their relationships with themselves as well as others. More specifically, suicide was represented as a collective ritual that enabled the people in the 1960s to help overcome the chaos and scars of the war in the 1950s and return to everyday life. In addition, suicide was a symbol of anti-Oedipus towards quasi-father, which was embodied in modern people’s mind as a schizophrenic symptom that exhibited ambivalent and contradictory feelings between growth and resistance. Finally, it represented love and the open-wide future with a more positive interpretation and meaning-making in contrast to the conventional tragic and terminal images attached to suicide. The 1960s novel has often been interpreted in terms of ‘conflict and resolution’ (resistance, contradiction, overcoming, and sublation) or dialectics (thesis-antithesis-synthesis). Also, its meaning has often been interpreted from a generational perspective. In contrast, this paper tried to interpret the 1960s novel in terms of the ethics of ‘suicide’ in order to prepare a basis for new interpretations and meanings. 본 연구는 1960년대 소설에 나타난 ‘자살’ 모티프를 중심으로 당대의 소설에 대한 지형도를 그리고 그 의미를 논구한다. 자살은 1960년대 소설을 특징 짓는 하나의 문학적 형식이었으며 내적 표상이었다. 또한 자살은 60년대 문인들이 진정한 자기세계를 구축하고 내적 윤리를 표상하는 하나의 형식이 되었다. 구체적으로 그것은 첫째, 60년대인들이 50년대 겪었던 전쟁의 혼란과 상흔을 털고 일상인으로서의 삶으로 복귀하게 하는 집단적 제의의 표상이 되었다. 둘째, 60년대 소설에서 자살은 의사(疑似) 아버지에 대한 앙띠 오이디푸스의 상징물로 나타났는데 성장과 저항의 양가적・모순적 감정을 가지고 있는 근대인들에게 그것은 분열적 증상으로 구체화되었다. 셋째, 60년대 소설 속의 자살은 사랑과 미래적 개방성으로 나타났는데, 이는 비극적 결말의 표지가 아니라 가장 적극적 해석과 의미의 확산을 가져오는 계기가 되었다. 1960년대 소설에 대한 기존의 연구는 시대에 대한 저항, 극복, 모순, 지양 등과 같은 ‘대립과 극복’의 구도, 혹은 변증법의 구도를 떠올리게 하는 정반합의 논리로써 수행된 바가 많았다. 또한 세대론적 관점에 대한 고찰로써 당대 문학 작품들의 의미를 구획화 하는 경우가 많았다. 본 연구는 이 시기의 소설들에 대한 새로운 의미규정의 축을 ‘자살’의 ‘윤리학’으로 구체화함으로써 새로운 해석과 의미생산의 지점들을 마련해 보고자 하였다.

장애인 관계법령에 따른 메뉴얼 및 지침서에 대한 비교연구 : 일본의 동경도 복지거리 만들기 조례와 한국의 장애인·노인·임산부 등의 편의증진보장에 관한 법률을 중심으로 Focusing on Tokyo Welfare Street Making Regulation in Japan and Facilities Advancement Security Act for Disabled People, the Elderly and Pregnant Women in Korea

송주현,김신원 韓國植物ㆍ人間ㆍ環境學會 2001 인간식물환경학회지 Vol.4 No.3

To establish the disabled facilities required by national laws, reference has been made to Tokyo welfare street making regulation in Japan and facilities advancement security act for disabled people, the elderly and pregnant women in Korea. My study has compared the differing standards relating to buildings and facilities, outdoor spaces and other amenities such as parking areas, doors, ramps, stairs etc, provided for the convenience of disabled people in both of countries. The objective of national laws has been to provide facilities suited to the special needs of disabled people and to remove barriers that would otherwise exclude them from areas or activities. Accordingly, the principal study has been to estimate about valuable guide disabled people as well as the general people then to make indiscriminate outdoor space so that disabled people must to travel provided facilities easily.

학교 숲 체험 활동 프로그램이 초등학생의 과학탐구능력과 과학에 대한 태도에 미치는 효과

송주현,이형철 대한지구과학교육학회 2018 대한지구과학교육학회지 Vol.11 No.3

본 연구는 학교 숲 체험 프로그램이 초등학교 학생의 과학탐구능력 및 과학에 대한 태도에 미치는 영향을 알 아보고 학교 숲 프로그램 개발 및 보급에 도움이 될 시사 점을 제시하는데 목적이 있다. 연구의 목적을 달성하기 위하여 실험반과 비교반을 정하고 사전검사 후, 실험반 은 자체 개발한 학교 숲 체험 활동 프로그램 10차시를, 비교반은 같은 차시 동안 사진 자료와 교사의 설명, 학습 지를 활용한 수업을 실시하였다. 수업 후 사후검사를 하 였고 실험반은 학교 숲 체험 활동 프로그램을 경험한 소 감을 인터뷰 형식으로 조사하였다. 본 연구의 결과는 다 음과 같다: 첫째, 학교 숲 체험 활동 프로그램이 학생들 의 과학탐구능력의 평균 점수에 있어서의 향상 폭이 비 교반 보다 더 크긴 했지만 그것이 유의미한 결과는 아닌 것으로 나타났다. 둘째, 학교 숲 체험활동 프로그램이 학 생들의 과학에 대한 태도 향상에 유의미한 효과를 나타 냄을 알 수 있었다. ‘과학의 사회적 의의’, ‘과학자의 평 범성’, ‘과학탐구에 대한 태도’, ‘과학 수업의 즐거움’, ‘과 학에 대한 취미로서의 관심’, ‘과학에 대한 직업으로서의 관심’ 등 모든 하위 영역에서 유의미한 효과가 나타났다. 그리고 인터뷰를 통하여 학생들은 학교 숲 체험 활동 프 로그램에 대해서 흥미롭게 생각했으며 만족도 또한 높았 음을 알 수 있었고 그것이 과학에 대한 태도가 긍정적으 로 향상하는데 기여했을 것으로 판단된다. The purpose of this study was to examine the effects of school forest activities program on elementary students’ science process skill and attitude toward science to make suggestions to help develop and extend the program. The subjects of the study were 49 students of two classes. One class of 24 students, experimental class, took developed 10 periods of school forest activities program. While the other class of 25 students, comparative class, took ordinary teacher driven periods using photo materials and study papers. Before and after the program, pre and post test were done. The results of this study can be summarized as follows: First, the school forest activities program didn’t have a meaningful effect on students' science process skill. Second, the school forest activities program had a meaningful effect on the improvement of students' attitude toward science. From the interview with experimental class, we could know that students had a favorable impression and high satisfaction level about the activities program.

The Effect of Agmatine on Expression of IL-1β and TLX Which Promotes Neuronal Differentiation in Lipopolysaccharide-Treated Neural Progenitors

송주현,이원택,박경아,강소망,Bokara Kiran Kumar,이종은 한국뇌신경과학회 2013 Experimental Neurobiology Vol.22 No.4

Differentiation of neural progenitor cells (NPCs) is important for protecting neural cells and brain tissue during inflammation. Interleukin-1 beta (IL-1β) is the most common pro- inflammatory cytokine in brain inflammation, and increased IL-1β levels candecrease the proliferation of NPCs. We aimed to investigate whether agmatine (Agm), a primary polyamine that protects neural cells,could trigger differentiation of NPCs by activating IL-1β in vitro. The cortex of ICR mouse embryos (E14) was dissociated to cultureNPCs. NPCs were stimulated by lipopolysaccharide (LPS). After 6 days, protein expression of stem cell markers and differentiationsignal factors was confirmed by using western blot analysis. Also, immunocytochemistry was used to confirm the cell fate. Agmtreatment activated NPC differentiation significantly more than in the control group, which was evident by the increased expressionof a neuronal marker, MAP2, in the LPS-induced, Agm-treated group. Differentiation of LPS-induced, Agm-treated NPCs wasregulated by the MAPK pathway and is thought to be related to IL-1β activation and decreased expression of TLX, a transcriptionfactor that regulates NPC differentiation. Our results reveal that Agm can promote NPC differentiation to neural stem cells bymodulating IL-1β expression under inflammatory condition, and they suggest that Agm may be a novel therapeutic strategy forneuroinflammatory diseases.

교통사고로 인한 편타성 손상 환자의 瘀血方 치료 효능에 관한 임상적 연구

송주현,조재희,이효은,강인,임명장,문자영,장형석 대한침구의학회 2007 대한침구의학회지 Vol.24 No.5

Objectives : The purpose of this study is to investigate the effect of eo-hyeol bang for patients with whiplash injury caused by a traffic accident. Methods : 60 patients were divided into two groups, Group A and Group B, of 30 patients each. Group A was treated with eo-hyeol bang twice per week for four weeks. Group B was treated with general acupuncture treatment twice per week for four weeks. Results : Between the two groups there was no significant difference in the VNRS score and the Neck disability index. Also, the study did not show significant difference between three variations of motion pattern induced pain and four stages based on the trauma duration of Group A. Conclusions : For patients with whiplash injury, eo-hyeol bang has not proven to be more effective than general acupuncture treatment.

Synthesis and Antiepileptic Activity Evaluation of Valproic Acid Derivatives by Niche Chemistry

송주현,배송미,Whae Ran Bae,Jin Sun Huh,Yu Chen,Il Soo Jeong,정대일 대한화학회 2020 Bulletin of the Korean Chemical Society Vol.41 No.5

In order to prepare new antiepileptic drugs with a broader clinical application and lower toxic side effects, we have employed esterification and condensation reactions (we call it Niche Chemistry) to reduce the use of valproic acid as the target molecule. In combination with the study of a broad-spectrum of novel anticonvulsants, we have synthesized two valeric acid derivative compounds [(4-acetamidophenyl 2-propylvalerate (1), and (E)-5-(4-((2-propylpentanoyl)oxy)styryl)-1,3-phenylene bis(2-propylvalerate) (2) by an esterification reaction. The maximum shock seizure test for products 1 and 2 has been successfully carried out, and their cytotoxic activity and survival effects have also been carefully investigated.

Spiro-β-lactams Synthesized from Imines Derived from 8-Azabicyclo[3.2.1]octan-3-ones

송주현,Yeon-geun Kwon,Hyun-Ok Lee,정대일,한정태 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.12

인공 고관절 치환술의 예방적 항생제 사용에 대한 진료가이드

송주현 건강보험심사평가원 심사평가연구소 2008 HIRA 정책동향 Vol.2 No.6