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Extrapulmonary Lymphangioleiomyoma: Clinicopathological Analysis of 4 Cases
송대현,한정호,최인호,하상윤,한강민,이재준,홍민의,최윤라,장기택,송상용,이진아 대한병리학회 2014 Journal of Pathology and Translational Medicine Vol.48 No.3
Background: Lymphangioleiomyomatosis (LAM) is a slowly progressive neoplastic disease that predominantly affects females. Usually, LAM affects the lung; it can also affect extrapulmonary sites, such as the mediastinum, the retroperitoneum, or the lymph nodes, although these locations are rare. A localized form of LAM can manifest as extrapulmonary lesions; this form is referred to as extrapulmonary lymphangioleiomyoma (E-LAM). Due to the rare occurrence of ELAM and its variable, atypical location, E-LAM is often difficult to diagnose. Herein, we report the clinicopathological information from four E-LAM cases, and also review previous articles investigating this disease. Methods: Four patients with E-LAM were identified at the Samsung Medical Center (Seoul, Korea) from 1995 to 2012. All E-LAM lesions underwent surgical excision. Results: All patients were females within the age range of 43 to 47 years. Two patients had para-aortic retroperitoneal masses, while the other two patients had pelvic lesions; two out of the four patients also had accompanying pulmonary LAM. In addition, no patient displayed any evidence of tuberous sclerosis. Histologically, two patients exhibited nuclear atypism with cytologic degeneration. Conclusions: E-LAM should be considered in the differential diagnosis of patients presenting with pelvic or para-aortic masses. We also conclude that further clinical and pathological evaluation is needed in patients with E-LAM and nuclear atypism.
" 노년기의 고독감 : 3 . ' 자녀와의 관계에서 파생된 고독감척도 ' 의 타당도 연구 "
송대현,윤가현 전남대학교 사회과학연구소 1990 현대사회과학연구 Vol.1 No.1
Content and sampling validity for the Youn loneliness scale (YLS), which is supposed to assess the perceived loneliness resulting from discordant relationship between aging Koreans and their offsprings, was found in this research. The sample consisted of 338 elderly Koreans between the ages of 50 and 85. Results was that the correlation between the YLS and Krause (1987) emotional support subscale of the social support items was -.433 (p$lt;.001) for the sample whereas the correlation between the YLS and Stones and Kozma (1989) happiness /depression subscale was -.478 (p$lt;.001). The YLS was interpreted as a useful tool for assessing aging Koeans' perceived loneliness resulting from the relationship between them and their offsprings.
아리스토텔레스의 『동물운동론』 10장에서 sumphuton pneuma
송대현 서강대학교 철학연구소 2011 철학논집 Vol.24 No.-
아리스토텔레스는 『동물운동론』 10장에서 "타고난 프네우마"(sumphuton pneuma)의 성격과 작용에 관하여 설명하고 있다. 이런 설명을 고찰하기 위하여 필자는 아리스토텔레스의 『동물운동론』, 703a4 -703a28에 대한 번역을 제시하면서 자세히 분석했다. 아리스토텔레스의 타고난 프네우마에 대한 빗나간 해석을 제거하기 위한 최선의 방법은 관련된 텍스트에 대한 정확한 독해라고 보았기 때문이다. 다음은 우리가 행한 분석과 독해의 요약이다. (1) 타고난 프네우마에 대한 일반적 규정을 제시한다. 타고난 프네우마는 운동을 하면서(운동을 겪으면서) 운동을 일으키는 것이다. 이것을 모든 동물들은 타고날 때부터 가지고 있고 이를 통해 힘을 얻어서 운동한다. (2) 타고난 프네우마는 심장에 있다는 것은 분명하다. 왜냐하면 운동의 근원은 심장에 있기 때문이다. (3) 타고난 프네우마는 다른 외적인 힘에 의하여 운동하지 않으며, 질적 변화를 통하지 않고 수축-증대를 통하여 운동을 일으킨다. (4) 타고난 프네우마는 질적 변화를 통하지 않고 요소들 간의 균형과 균형의 파괴에 의해서 운동을 일으킨다. 이런 분석을 통해서 우리가 확인한 것은, 아리스토텔레스에 의하면, 모든 동물이 타고날 때부터 가지게 되는 타고난 프네우마는 심장에 위치에 있으며, 자신이 운동을 겪으면서 수축-증대를 통하여 다른 것을 운동하게끔 하는 것이다. 이런 프네우마는 동물운동의 도구이며 물질적인 것으로 이해해야 한다. 또한 『동물운동론』 10장에서 언급되는 타고난 프네우마는 에테르 혹은 물과 동일시 될 수 없다는 것은 분명하다. 이런 동일시를 보증해주는 텍스트 전거를 우리는 발견할 수 없기 때문이다. Aristote explique la nature et le role du sumphuton pneuma (SP) dans son petit traite intitule De motu animalium, plus precisement au ch. 10, 703a4-28. Voici les resultats de notre analyse, qui permet de rejeter deux interpretations eloignees du texte aristotelicien, selon lesquelles le SP pourrait etre identifie soit a l'Ether, soit a l'Eau: (1) Le SP est le moteur mu qui produit les mouvements des autres parties du corps. (2) Le SP se trouve dans le cœur. (3) Le SP mets en mouvement les autres parties du corps en exercant d'une contraction et d'une dilation. (4) Le SP produit le mouvement a l'instar des interrelations d'entre les elements sublunaires sans qu'un changement qualitatif n'intervienne. Ces analyses se ramenent aux deux points suivants. D'une part, le SP localise dans le cœur provoque le mouvement des autres parties par l'intermediaire d'une contraction et d'une dilation; par consequent, il est evident que le SP est l'instrument corporel des mouvements. D'autre part, il n'est pas convaincant que, dans le De motu animalium, ch. 10, le SP soit identique a l'ether (aither) ou a l'Eau. En effet, le texte d'Aristote ne permet pas d'identifier le SP a l'un ou a l'autre.
Large Cell Calcifying Sertoli Cell Tumor of the Testis: A Case Study and Review of the Literature
송대현,이종실,정성묵,박종탁,윤각원,김병권 대한병리학회 2014 Journal of Pathology and Translational Medicine Vol.48 No.1
A 24-year-old man was admitted due to an incidentally detected mass in his left testis, which showed radiopaque calcification on plain X-ray film. Left orchiectomy was performed, and the resected testis contained a well-demarcated, hard mass measuring 1.1 cm. Histological analysis revealed that the tumor was composed of neoplastic cells, fibrotic stroma, and laminated or irregularly shaped calcific bodies. The individual cells had abundant eosinophilic or clear cytoplasm with round nuclei, each of which contained one or two conspicuous nucleoli. They were arranged in cords, trabeculae, clusters, and diffuse sheets. There were several foci of intra-tubular growth patterns, with thickening of the basal lamina. Immunohistochemically, the neoplastic cells were positive for S-100 protein and vimentin, focally positive for inhibin alpha, and negative for cytokeratin, CD10, and Melan-A. In addition to reporting this rare case, we also review the relevant literature regarding large cell calcifying Sertoli cell tumors.