http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
손동욱,이찬우,정영국,조래정,이혜경,김은실,이진수,정문현 대한감염학회 2007 Infection and Chemotherapy Vol.39 No.6
Meningococcal infection is a life threatening disease that leaves serious sequelae in spite of appropriate treatment, thus vaccination for high risk groups are important for the prevention of meningococcal diseases. However, the vaccine for Neisseria meningitidis has not been available in Korea until we introduced bivalent (serogroup A and C) polysaccharide vaccine for the first time for relief works in our university hospital. The vaccine was administered from January 2005 to March 2007 to 317 persons. Of the groups administered, the largest group among them were 133 (133/317, 42%) students who planned to study abroad and needed the vaccination for secure entrance to school dormitories. This group was followed by health care workers, travellers to the regions of the world with high risks of meningococcal diseases, and splenectomised patients. To rationalize the domestic use of meningococcal vaccine, the availability of vaccines first needs to be simplified by introducing them to the domestic market; for this to be possible, the approval system for vaccines should be reformed and epidemiogical studies need to be carried out.
Ventrally Located Cervical Dumbbell Ganglioneuroma Producing Spinal Cord Compression
손동욱,송근성,김영하,이상원 대한척추신경외과학회 2013 Neurospine Vol.10 No.4
Ganglioneuroma is an uncommon benign tumor and arise from neural crest cells or sympathetic and peripheral nerves. A 13-year-old boy was referred to our institute and presented with three-day history of right upper extremity weakness associated with neck pain for nearly one month. Magnetic resonance imaging showed right side dumbbell shaped extramedullary lesion at the C2-3 level extending outside through neural foramen. Paraspinal and posterior neck mass, cafe au lait spot was identified. We performed surgical decompression of the spinal cord by resection of intradural portion mass. Histopathological diagnosis was ganglioneuroma.
In vitro Synergism between Chloroquine and Antibiotics against Orientia tsutsugamushi
손동욱,정문현 대한감염학회 2014 Infection and Chemotherapy Vol.46 No.3
Background: To investigate whether chloroquine enhances the effect of antibiotics against Orientia tsutsugamushi, the causativeorganism of scrub typhus, we compared the effect of antibiotics in combination with chloroquine with the effect of antibioticsalone in vitro. Materials and Methods: The Boryong or AFSC-4 strain was inoculated into ECV304 cells, and incubated in medium containingdoxycycline (4 μg/mL), rifampin (4 μg/mL), azithromycin (0.5 μg/mL), chloroquine (1 μg/mL), and each of these antibiotics incombination with chloroquine for 7 d. Immunofluorescence (IF) staining for O. tsutsugamushi was performed 4 hr and 7 d afterinoculation of the bacteria, and IF-positive foci were enumerated. Results: Chloroquine inhibited the growth of O. tsutsugamushi by 15.5%. In combination with chloroquine, the antimicrobialeffects increased by 4.4% for doxycycline (a 92.9% reduction of bacterial numbers for doxycycline versus a 97.3% reductionfor doxycycline plus chloroquine), 4.6% for rifampin (90.0% versus 94.6%), and 8.3% for azithromycin (86.9% versus 95.2%). The antimicrobial effect of the antibiotics alone was significantly different compared to the combined effect of antibiotics andchloroquine (Wilcoxon signed-rank test, P = 0.001). Conclusions: The combined use of chloroquine with an antibiotic for the treatment of O. tsutsugamushi infections may be usefulfor increasing the efficacy of the antibiotics.
장딴지근의 근힘줄 조직특성에 대한 정적 스트레칭과 동적 스트레칭의 효과 비교
손동욱,심재훈 한국신경근육물리치료학회(구 한국신경근육재활학회) 2015 한국신경근육재활학회지 Vol.5 No.1
The objective of this study is to determine the effects of static and dynamic stretching exercises on the gastrocnemius muscle-tendon properties by use of ultrasonography. Twenty healthy adults participated in the present study. The subjects were asked to engage in static and dynamic stretching exercises of the gastrocnemius for 30 sec each in 2 sets. Ultrasonography to measure the displacement of the myotendinous junction (MTJ) was performed at the 0 sec, 30 sec, 60 sec, 180 sec, and 300 sec after the stretching exercises. A significant displacement of the static stretching was observed between the 0 sec and 30 sec, and between the 180 sec and 300 sec (p<0.05), with no significant changes between the 30 sec and 180 sec. And dynamic stretching exercise showed more significant displacement in the all conditions compared with static stretching (p<0.05). The displacement of the MTJ position was observed in proximal parts, and dynamic stretching appeared to make the change in distal parts. Therefore, static and dynamic stretching exercises of the gastrocnemius showed different change rate and position displacement direction.
손동욱,황수진 물리치료재활과학회 2017 Physical therapy rehabilitation science Vol.6 No.3
Objective: Robot assisted gait training is implemented as part of therapy for the recovery of gait patterns in recent clinical fields, and the scope of implications are continuously increasing. However clear therapy protocols of robot assisted gait training are insufficent. The purpose of this study was to investigate the effects of robot-assisted gait training applied with guidance force on balance and gait performance in persons with hemiparetic stroke. Design: Two group pre-test post-test design. Methods: Nineteen persons were diagnosed with hemiparesis following stroke participated in this study. The participants were randomly assigned to the unilateral guidance group or bilateral guidance group to conduct robot-assisted gait training. All participants underwent robot-assisted gait training for twelve sessions (30 min/d, 3 d/wk for 4 weeks). They were assessed with gait parameters (gait velocity, cadence, step length, stance phase, and swing phase) using Optogait. This study also measured the dynamic gait index (DGI), the Berg balance scale (BBS) score, and timed up and go (TUG). Results: After training, BBS scores were was significantly increased in the bilateral training group than in the unilateral guidance group (p<0.05). Spatiotemporal parameters were significantly changed in the bilateral training group (gait speed, swing phase ratio, and stance phase ratio) compared to the unilateral training group (p<0.05). Conclusions: The results of this study suggest that robot-assisted gait training show feasibility in facilitating improvements in balance and gait performance for subacute hemiparetic stroke patients.