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정현우,김종석,세영배,서강현,김승훈,강성현,신동진,이창래,김규석,이영진 한국광학회 2016 Current Optics and Photonics Vol.20 No.6
In single-photon-emission computed tomography (SPECT) with a pixelated semiconductor detector(PSD), not only pinhole collimators but also parallel-hole collimators are often used in preclinicalnuclear-medicine imaging systems. The purpose of this study was to evaluate and compare pinhole andparallel-hole collimators in a PSD. For that purpose, we paired a PID 350 (Ajat Oy Ltd., Finland) CdTePSD with each of the four collimators most frequently used in preclinical nuclear medicine: (1) a pinholecollimator, and (2) low-energy high-resolution (LEHR), (3) low-energy general-purpose (LEGP), and (4)low-energy high-sensitivity (LEHS) parallel-hole collimators. The sensitivity and spatial resolution of eachcollimator was evaluated using a point source and a hot-rod phantom. The highest sensitivity was achievedusing LEHS, followed by LEGP, LEHR, and pinhole. Also, at a source-to-collimator distance of 2 cm,the spatial resolution was 1.63, 2.05, 2.79, and 3.45 mm using pinhole, LEHR, LEGP, and LEHS,respectively. The reconstructed hot-rod phantom images showed that the pinhole collimator and the LEHRparallel-hole collimator give a fine spatial resolution for preclinical SPECT with PSD. In conclusion, wesuccessfully compared different types of collimators for a preclinical pixelated semiconductor SPECTsystem.