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- 저자 : 성혜숙 ( Hae Sook Sung ) (검색결과 3 건)
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박해근,김광진,성혜숙,전병숙,Park, Hae-Kun,Kim, Kwang-Jin,Sung, Hae-Sook,Jeon, Byung-Sook 대한생리학회 1977 대한생리학회지 Vol.11 No.2
The maximum voluntary ventilation (MVV) is one of the most widely used pulmonary function test, but its measuring method was very difficult and unreliable. However, it is need to get more easy and simple measuring method of MVV. Therefore, this study was attempted to get more easy and simple measuring method of MVV by means of the forced expiratory volume $(FEV_{T})$. The young and healthy 1,000 Korean students(592 male and 408 female) were cheesed for this purpose and whose ages were from 8 to 20 years. A spirometer (9L, Collins Co.) was used for the MVV and FEV, and they were measured 3 times at standing position, and the highest value was used. In the measurements, the subjects for MVV were asked for the breath as fast and deeply as possible for 12 seconds, and for FEV were asked for the rapid and forceful exhalation after a maximal inhalation (forced expiratory curve). In the FEV measurements toward the end of the expiration, the subjects were exhaused to continue the effort until no further gas was expired. During these measurements, the investigator stood by the subject to give a constant encouragement. FEV were calculated in the volume exhaled during the one-half $(FEV_{0{\cdot}5,}\;ml)$, the first second $(FEV_{1{\cdot}0,}\;ml)$ and the percentage of the total vital capacity exhaled during the one-half second $(FEV_{0{\cdot}5,}\;%)$. The results are summarized as follows: 1) The values of MVV were increased linearly with ages until 20 in both sexes. The values of male at the age of 20 was $168.2{\pm}2.5L/min$, and female at the age of 17 was $112.3{\pm}3.0L/min$, respectively. 2) The values of FEV (ml) were increased linearly with ages until 20 in both sexes. The values of $FEV_{0{\cdot}5}$ were $2,797{\pm}65.7ml$ in the male of 20 years and were $2,088{\pm}54.6ml$ in the female of 17 years, and of $FEV_{1{\cdot}0$ were $4,119{\pm}68.2ml$ in the male of 20 years and were $2,897{\pm}65.9ml$ in the female of 17 years, respectively. 3) The correlation coefficients between MVV and $FEV_{0{\cdot}5}\;or\;FEV_{1{\cdot}0$ (ml) were 0.82 or 0.85 in the male, and 0.77 or 0.79 in the female, respectively. 4) The prediction formulae for MVV to be derived from above results were: For male: MVV (L/min) =7.19+$0.05{\times}FEV_{0\cdot5}(ml)$, MVV (L/min)=11.25+$0.04{\times}FEV_{1\cdot0}(ml)$ For female: MVV (L/min)=16.03+$0.05{\times}FEV_{0\cdot5}(ml)$, MVV (L/min)=9.47+$0.03{\times}FEV_{1\cdot0}(ml)$.
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成惠淑,金光鎭 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.1
Orostachys malacophyllus F. has been applied in Chinese medicine as well as in folk remedy. Its chemical composition and pharmacological actions have not reported yet. But, sometimes, it was used in treatment for the stomach or lung cancer. This study was attempted to investigate the effects of the water fraction separated from alcohol extract of the plant on the renal functions of rabbits. After cannulation of carotid artery, jugular vein and ureters were prepared for the recording of blood pressure, the infusion of the water extract(0.005%) or the hypotonic saline(0.45%), and the collection of the urine, respectively. The hypotonic saline was infused to hydrate the rabbits, and the mixed solution of hypotonic saline, PAH, and inulin was infused to measure the glomerular filtration rate(GFR) and renal plasma flow (RPF). After the hydration, the changes of urine volume were obsereved during the infusion of the water fraction for 1 hour, and during the infusion of hypotonic saline for 80min. And the concentration of PAH or inulin in the urine and blood was measured by the method of Smith and the method of Schreiner, electrolyte concentration by flamephotometer, and the osmolar conentration by osmometer, respectively. The results were summarized as follows: 1. Urine volume, GFR, and RPF were decreased significantly by the infusion of water fraction, and thery were not recovered to control values after the exchange to hypotonic saline. 2. Filtration fraction was increased by water fraction. 3. Water fraction decreased the plasma clearances of electrolytes and the osmolar substances, and increased the negative free water clearance. 4. Water fraction increased the reabsorptive rate(%)of potassium, and decreased the excretory amount of Na or K. And it was decreased the ratio of Na/K excretion. From the above results, it was suggested that water fraction has the antidiuretic effect and its mechanism is primarily caused by the change of the renal hemodynamics.
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