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실험적 간질을 유발한 흰쥐에서 선택적 편도핵절제술의 효과
성우현,성기원,이재수,최창락 대한신경외과학회 1991 Journal of Korean neurosurgical society Vol.20 No.5
In order to study the effects of stereotaxic destruction of distinct epileptogenic focus, the amygdala was destroyed with radiofrequency coagulator. A total of twenty Sprague-Dawley rats were divided into two groups : the control group which underwent craniectomy on the biparietal area and was instilled crytal penicillin solution into the right amygdala on the basis of sterotaxic coordinates(n=10), and the amygdalectomy group which was performed selective amygdalectomy with radiofrequency coagulator after confirmation of clinical and electroencephalographic epileptic features after proceeding same methods of control group(n=10). The experimental epileptic models in rats were obtained by selective instillation of crystal penicillin solution into the right amygdala. The effects of amygdalectomy were investigated by observation of the canges in behavior and electroencephalographic recordings. The results were as follows; 1) A typical behavioral seizure was shown in the control group and epilepticform discharge was prominent in crystal penicillin solution instilled side, but there was no bilateral synchronous epileptic discharges during ictal stages. 2) In comparision to two groups, the severity and the frequency of behavioral seizure were more decreased in the stereotaxic amygdalectomy group. 3) The amygdalectomy group was shwon a significant decrease in amplitude and frequency of spikes, especially during interictal stages, compared to the control group. From the results of electroencephalographic and behavioral analysis, selective amygdalectomy with radiofrequency coagulator seemed to be an effective method to treat the crystal penicillin solution induced epileptic rats.
완전 적출 후 조기 재발된 양성 뇌수막종 1례 : Case Report
성우현,박춘근,김문찬,김달수,강준기,송진언 대한신경외과학회 1986 Journal of Korean neurosurgical society Vol.15 No.1
The average interval from first operation to recurrence is about 4 years and the reported shortest interval of malignant meningioma is about 6 months. The authors reported a case of rapidly regrowing benign meningioma. located on the outer 1/3 of the right sphenoid wing. The patient was free of recurrence only at 4 months after the first surgery in spite of macroscopic complete removal of the tumor. Factors associated with recurrence of meningioma are also discussed.
성우현,이일우,조태훈,송진언 대한신경외과학회 1986 Journal of Korean neurosurgical society Vol.15 No.4
Intracranial lipomas are rare tumor which are usually found at or near the mid saggital plane, especially in the corpus callosum. 3 cases of intracranial lipomas, diagnosed by CT scanning, are presented. The first case was a lipoma involving the midline of occiput to the bilateral occipital lobes through the skull defect. There was a calcified area in this tumor. The second case presented a generalized convulsive seizure as clinical manifestation, and the lipoma was found to be located in the corpus callosum. In the third case, the lipoma was located near the third ventricle and the tumor was found incidentally after head trauma. The first case was operated and the tumor was completely removed, the others were managed with symptomatic treament. The literature on this rare tumor is reviewed and discussed.
Clinical Results of Radiosurgery in CUMC
성우현,윤세철,최창락,최규호,강준기,서태석,전신수,박춘근,김문찬 가톨릭중앙의료원 가톨릭암센터 1995 암심포지움 Vol.- No.1
가톨릭대학교 의과대학 강남성모병원에서는 1988년부터 진단방사선과, 치료방사선과 및 신경외과의 공동연구로서 Radiosurgery를 실시하였으며, 지난 7년간에 137예의 환자에 대해 6 McV Lincar accelerator를 이용한 치료를 시행하였다. 이중 67예에 대해 그 치료결과를 분석하였다.