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세 종류의 비구면 인공수정체 간의 술 후 구면수차, 대비감도 및 초점심도 정도의 비교
배형원,김응권,김태임 대한안과학회 2009 대한안과학회지 Vol.50 No.11
목적: 세 가지 종류의 비구면 인공수정체 삽입 후 구면수차, 대비감도 및 초점심도를 평가하고자 하였다. 대상과 방법: Akreos adapt Advanced Optics (AO) (18안), AcrySof IQ SN60WF (20안), Tecnis Acrylic IOL ZA9003 (18안), 총 48명 56안을 대상으로 술 후 3개월째 고위수차 및 구면수차를 포함한 안구 전체 및 안구 내 수차와 대비감도를 측정하고, 원거리시력을 교정 한 상태에서 33 cm 및 1 m 시력을 이용한 초점심도를 평가하였다. 결과: 전체 구면수차 및 안구 내 구면수차에 있어 AO를 삽입 받은 군이 다른 두 군에 비해 다소 높은 구면수차 값을 보였으나, 결과적 으로 대비감도 및 초점심도 정도에 있어서는 세 군간에 있어 유의한 차이는 발견되지 않았다. 결론: 세 군간 대비감도 및 초점심도에 유의한 차이를 보이지 못한 것은 세 군간 구면수차의 차이가 크지 않고 구면수차를 제외한 다른 요인들 간에 차이가 없어 대비감도 및 초점심도에 큰 영향을 주지 못한 것으로 생각된다. Purpose: To evaluate postoperative spherical aberration, contrast sensitivity and depth of focus after implanting 3 different aspheric intraocular lenses. Methods: Fifty-six eyes (18 eyes for Akreos adapt Advanced Optics (AO), 20 eyes for AcrySof IQ SN60WF and 18 eyes for Tecnis Acrylic IOL ZA9003) of 48 patients were evaluated. Internal ocular aberration including spherical aberration and higher-order aberration and contrast sensitivity were evaluated 3 months after lens implantation. In addition, visual acuities at 33 cm and 1 m distance were measured with the far vision corrected state to calculate depth of focus. Results: The total and internal ocular spherical aberration of the AO implanted group was slightly higher than the other groups with statistical significance. However, there was no statistically significant difference of contrast sensitivity and depth of focus among the 3 groups. Conclusions: A subtle difference of spherical aberration among the 3 groups without a statistically significant difference in other factors may not induce the differences of contrast sensitivities and depths of focus in each group.
배형원,이상엽,김상아,박찬금,이광현,김찬윤,성공제 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.1
Purpose: To assess whether the asymmetry in the peripapillary retinal nerve fiber layer (pRNFL) thickness between superior and inferior hemispheres on optical coherence tomography (OCT) is useful for early detection of glaucoma. Materials and Methods: The patient population consisted of Training set (a total of 60 subjects with early glaucoma and 59 normal subjects) and Validation set (30 subjects with early glaucoma and 30 normal subjects). Two kinds of ratios were employed to measurethe asymmetry between the superior and inferior pRNFL thickness using OCT. One was the ratio of the superior to inferior peak thicknesses (peak pRNFL thickness ratio; PTR), and the other was the ratio of the superior to inferior average thickness (averagepRNFL thickness ratio; ATR). The diagnostic abilities of the PTR and ATR were compared to the color code classification in OCT. Using the optimal cut-off values of the PTR and ATR obtained from the Training set, the two ratios were independently validatedfor diagnostic capability. Results: For the Training set, the sensitivities/specificities of the PTR, ATR, quadrants color code classification, and clock-hour color code classification were 81.7%/93.2%, 71.7%/74.6%, 75.0%/93.2%, and 75.0%/79.7%, respectively. The PTR showed a better diagnostic performance for early glaucoma detection than the ATR and the clock-hour color code classification in terms of areas under the receiver operating characteristic curves (AUCs) (0.898, 0.765, and 0.773, respectively). For the Validation set, the PTR also showed the best sensitivity and AUC. Conclusion: The PTR is a simple method with considerable diagnostic ability for early glaucoma detection. It can, therefore, be widely used as a new screening method for early glaucoma.
배형원,김지현,김상아,김민교,이나은,홍사민,성공제,김찬윤 고려인삼학회 2015 Journal of Ginseng Research Vol.39 No.1
Background: Many patients with glaucoma have difficulty using antiglaucoma eye drops because of dryeye symptom. In this prospective, randomized, double-blind, placebo-controlled study, we evaluated theeffect of Korean Red Ginseng on dry eye syndrome in patients with glaucoma treated with antiglaucomaeye drops. Methods: Forty-nine participants were allocated to the Korean Red Ginseng (3 g/day; n ¼ 24) or placebo(n ¼ 25) groups for 8 weeks. Tear film stability, fluorescein corneal staining, conjunctival hyperemia, tearproduction, grade of meibomian gland dysfunction, and dry eye questionnaire (Ocular Surface DiseaseIndex) were evaluated at baseline and on completion of the treatment. Results: Almost all patients displayed dry eye symptoms and signs at baseline. After the 8-week intervention,Korean Red Ginseng supplementation significantly improved the tear film stability and totalOcular Surface Disease Index score, as compared to placebo (p < 0.01). Conclusion: Korean Red Ginseng supplementation may provide an additional treatment option for dryeye and patients with glaucoma using antiglaucoma eye drops.