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      • KCI등재

        Conjugation of Ginsenoside Rg3 with Gold Nanoparticles

        박유미,A-Rang Im,Eun Ji Joo,Jihye Lee,형근,강영화,Robert J. Linhardt,Yeong Shik Kim 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.1

        Ginsenoside Rg3 was reported to have important biological activities. We demonstrate conjugation and quantification procedures of ginsenoside Rg3 to gold nanoparticles for future biological and medical applications. Ginsenoside Rg3was conjugated to spherical gold nanoparticles using a bifunctional heptaethylene glycol linker. The sulfhydryl group of heptaethylene glycol was adsorbed onto gold nanoparticles, and carboxylic acid end of heptaethylene glycol was bonded through a hydroxyl group of Rg3 via ester bond formation. The conjugation of Rg3 was characterized with various spectroscopic techniques, high resolution-transmission electron microscopy, and using Rg3 monoclonal antibody. The Rg3- functionalized gold nanoparticles were 4.7 ± 1.0 nm in diameter with a surface charge of ‒4.12 mV. The total number of Rg3 molecules conjugated to a 3.6 mL solution of gold nanoparticle was determined to be 9.5 ×10^14 corresponding to ~6 molecules of Rg3/gold nanoparticle. These results suggest that ginsenoside Rg3 is successfully conjugated to gold nanoparticles via heptaethylene glycol linker. The quantification was performed by using Rg3monoclonal antibody without interference of gold’s intrinsic color.

      • KCI등재

        『三國遺事』 <惠通降龍> 설화의 공간과 인물 관계

        박유미 한민족어문학회 2014 韓民族語文學 Vol.0 No.68

        In “Hyetong Hangryong,” a folk tale in Samguk Yusa, the main characters Hyetong and a dragon leave their places in order to resolve their problems. While Hyetong's problems are resolved well, the dragon's problems are not easily resolved. They move in different directions, but they sometimes happen to meet. In the same space, they confront each other, pushing and being pushed. The one who pushes his opponent solves his problems, and the other one being pushed does not solve his problems. In order to resolve the problems of each of the characters, the spaces presented in the folk tale are classified into three parts: A, B and C. In A, the characters overpower the space. In this space, the status of one character rises while that of the other is downgraded. In B, where characters secure their power, the space overpowers the characters. The statuses of the two characters are secured, but fail to make harmony. However, in C, the two characters achieve harmony without their statuses being downgraded. The C space, after all, has turned out to be ideal through “Hyetong Hangryong” from Samguk Yusa. When this is applied to all the tales of dragons in Samguk Yusa, it is found that Ilyeon presents the C space, the space where high and low classes naturally achieve harmony based on Buddhism, through folk tales of dragons in Samguk Yusa. 『삼국유사』의 <혜통항룡> 설화에서 중심인물인 혜통과 용은 각자 그들에게 생긴 문제를 해결하기 위해 이동을 감행한다. 혜통의 문제는 잘 해결되는 데 비해 용의 문제는쉬이 해결되지 않는다. 각 인물의 행보는 차이가 있으나 만나게 되는 경우가 생긴다. 그들은 동일한 공간 안에서 서로 대치되어 밀어내고 밀려나간다. 밀어내는 인물은 문제를 해결하고 밀리는 인물은 문제를 해결하지 못한다. 각 인물들의 문제 해결을 통해 설화에 제시된 공간은 A, B, C로 나타났다. A공간은인물이 공간을 지배하는 경우이다. 이 공간에서는 한 인물의 위상이 높아지기는 했으나다른 인물의 위상은 격하되었다. 인물이 세력을 확보하는 경우인 B공간은 공간이 인물을지배하여 두 인물 모두의 위상이 확보되기는 했으나 서로 조화를 이룰 수 있는 공간은되지 못했다. 하지만 C공간에서는 두 인물의 위상을 떨어뜨리지 않으면서 서로 조화를이룰 수 있도록 하였다. 결국 『삼국유사』<혜통항룡>을 통해 C공간이 이상적임을 드러내 주었다. 이를『삼국유사』 용설화 전반에 적용시켜 보았다. 일연은 『삼국유사』 용설화를 통해 C공간 즉, 상층과 하층이 불교신앙을 중심으로 자연스럽게 조화를 이루는 공간을 제시하고 있었다.

      • KCI등재후보

        모성 상실을 경험한 여성의 조형양상

        박유미(朴裕美) 한국일본문화학회 2016 日本文化學報 Vol.0 No.71

        I analyzed the formative features of the characters in the Murakami Haruki short story 「Thailand」and 「Drive․My․Car」. Both stories are organized in a similar pattern and had women who lost their children, which is uncommon in Haruki"s novels. Satsuki in 「Thailand」has the distorted thinking between maternalism and feminity because of the experience of abortion in the past. In 「Drive․My․Car」, the death of Kafuku"s daughter from a congenital disease made his wife constrain her life as a woman and give up herself as mother. Whether it was willful or against her will, women who had lost their maternalism started to have distorted thoughts of maternalism and feminity while they obsessed about their feminity. The characters that lead the main characters in the way of healing are described as the characters who varied from the social norm and have both male and female tendencies. Therefore, they perform as the advisors role with their unbiased and balanced thought.

      • 낭성 담도 확장을 동반한 담도 유두종증 1예

        박유미,이광원,윤선옥,하지윤,소영,이정호,장성일 영남대학교 의과대학 2012 Journal of Yeungnam Medical Science Vol.29 No.2

        A 61-year-old male who complained of right upper quadrant pain was referred to the authors for evaluation after his computed tomography suggested biliary adenocarcinoma. The lesion consisted of multiple cysts with papillary mass and peri-ampullay mass. The patient underwent an operation due to a clinical suspicion of biliary cystadenocarcinoma, but the pathology confirmed biliary papillomatosis(BP) after diagnosing intrahepatic papillary neoplasm with high-grade dysplasia and invasive adenocarcinoma with papillary neoplasm from the distal common bile duct to the duodenum. BP is a disease characterized by multiple papillary masses. Its cause has yet to be discovered. It commonly manifests as bile duct dilation but rarely as a ductal cystic change. Under computed tomography or magnetic resonance imaging, both the BP and the cystic neoplasm can show bile duct dilation and a papillary mass, which makes their differential diagnosis difficult. A confirmative diagnosis can be made through a pathologic examination. BP is classified as a benign disease that can become malignant and may recur, though rarely. Its treatment of choice is surgical resection. Laser ablation or photodynamic therapy can be used for unresectable lesions. In the case featured in this paper, biliary papillomatosis was difficult to differentiate from cystic adenocarcinoma due to diffusely scattered multiple large cystic lesions in the liver, and it was histologically confirmed to have become malignant with cystic duct dilation after the operation. This case is reported herein with a literature review.

      • KCI등재

        구약에 나타난 혼외 자녀 연구를 통한 교회의 포용성 넓히기

        박유미 한국구약학회 2022 구약논단 Vol.28 No.2

        The purpose of this thesis is to present the basis for the church to take an inclusive stance toward children out of wedlock through the study of children out of wedlock in the Old Testament texts. For this purpose, I dealt with ‘Mamzer’ in Deuteronomy 23:2, the narrative of Jephthah (Judges 11), the narrative of Tamar (Genesis 38), and Isaiah 56. In chapter 2, it was concluded that the mamzer of Deuteronomy 23:2 should be limited to a special term for a child born through incest. In Chapter 3, through the study of the Jephthah and Tamar narratives, it was found that male out-of-married men are viewed negatively by the family or community, but are not discriminated against legally or in terms of property with their legitimate children. In contrast, if a woman conceives a child out of wedlock, the law of Deuteronomy applies and she is sentenced to death. Due to the patriarchal culture of the Old Testament, there is a very big difference in the status, rights, and social perceptions of the husband's children out of wedlock and the wife's children out of wedlock. In chapter 4, I tried to read Deuteronomy 23 in the light of Isaiah 56. Here, the stranger symbolizes a group of people with innate limitations, and the eunuch symbolizes a group of people with limitations due to acquired actions or factors. The condition for their acceptance into the community of Jehovah is that they do justice and righteousness, and keep Jehovah's law, covenant, and sabbath. In other words, if you make a covenant with Jehovah and keep that covenant, you will be recognized as God's people and accepted into Jehovah's community. In conclusion, as the church is a New Testament community that has opened a new era, we should no longer view unwed mothers and children out of wedlock negatively, exclude them from the church, criticize them, or do anything that disadvantages them.

      • KCI등재후보

        열왕기서에서의 이방여성에 대한 재평가

        박유미 한국복음주의구약신학회 2019 구약논집 Vol.15 No.-

        This paper studies four foreign women appearing in the first Book of the Kings. I opposes the traditional view that all foreign women are seducers who make them worship idols. A study of four foreign women appearing in the first Book of the Kings found that not all of them were painted negatively. The queen of Sheba was the one who tested and recognized Solomon's wisdom. Then the widow of Sarbat acknowledged that Elijah was a true prophet of Jehovah and saved Elijah's life. So the queen of Sheba and the widow of Sarbat are all positive figures, and they acknowledge that Jehovah is the true God and praise him for his glory. But Solomon's wives and Jezebel brought the Gentiles to Israel, and made his husband worship idols and idolatry flourish in Israel. In particular, Jezebel was the most negative figure. Because she killed Jehovah's prophet and killed Naboth and helped Ahab take possession of Naboth's vineyard. But But more importantly, it is Solomon and Ahab's role in bringing the Gentile woman into Israel. They married foreign princesses for economic and military benefits and brought idols to Israel. The first Book of the Kings shows a balanced view of foreign women by featuring two positive foreign women and two negative foreign women. In other words, the book does not view the existence of foreign women negatively. But among the foreign women, they are wary of the wives of kings who married kings and brought the Gentiles into Israel. And through these warning, they warn Israel men that they should be careful about marrying foreign women. 이 논문은 열왕기상에 나타나는 4명의 이방여성들에 대해 연구하고 있다. 이방여성은 모두 우상을 섬기게 만드는 유혹자로 보는 전통적인 견해에 반대하며 열왕기상에 나타나는 네 명의 이방여성에 대한 연구를 통해 이방여성이 모두 부정적으로 그려지고 있지 않다는 것을 발견하였다. 스바의 여왕은 솔로몬의 지혜를 시험하고 인정한 인물이다. 그리고 사르밧 과부는 엘리야가 진정한 여호와의 선지자라는 것을 인정하였고 엘리야의 생명을 살려주었다. 이렇게 스바의 여왕과 사르밧 과부는 긍정적인 인물로 모두 여호와가 진정한 하나님이라는 것을 인정하고 그의 영광을 찬양한다. 하지만 솔로몬의 아내들과 이세벨은 이스라엘 땅에 이방신을 가져오고 자신의 남편이 우상을 섬기게 하고 이스라엘 땅에 우상 숭배가 성행하게 만들었다. 특히 이세벨은 여호와의 선지자를 죽였고 나봇을 죽이고 아합이 나봇의 포도원을 차지할 수 있도록 도운 부정적인 인물이다. 하지만 여기서 더 중요한 것은 이방여성을 이스라엘로 들어오게 한 솔로몬과 아합의 불 신앙적 태도이다. 이들은 경제적, 군사적 이익을 위해 이방의 공주들과 결혼하고 우상을 이스라엘에 들여왔던 것이다. 이렇게 열왕기상은 2명의 긍정적인 이방여성과 2명의 부정적인 이방여성을 등장시킴으로 이방여성에 대한 균형 잡힌 시각을 보여준다. 즉, 열왕기서 화자는 이방여성이라는 존재에 대해 부정적으로 보지 않는다. 다만 이방여성들 중에 왕들과 결혼하며 이방신을 이스라엘 땅으로 가지고 들어온 왕의 부인들에 대해서 경계를 하고 있는 것이다. 그리고 이런 경계를 통해서 이방여성과의 결혼에 대해서 신중해야 한다고 이스라엘 남성들에게 경고를 보내는 것이다.

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