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자궁경부 세포진검사에서 비정형 편평세포의 질적 세분화의 임상적 의의
조미영(Mi Yeong Jo),박영한(Young Han Park),유희석(Hee Sug Ryu),주희재(Hee Jae Joo),이원종(Won Jong Lee),장기홍(Ki Hong Chang),이정필(Jung Pil Lee),오기석(Kie Suk Oh) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.11
N/A Objective : The Bethesda System (1991) recommended that the diagnosis of atypical squamous cells of undetermined significance (ASCUS) be qualified when possible to indicate whether a reactive process, or premalignant/malignant process, is favored. In order to evaluate the clinical significance of the qualification, we reviewed our hospital`s experience with cervicovaginal smears diagnosed as ASCUS. Method : A retrospective study from June 1994 to December 2000 was performed on all cervicovaginal smears with the diagnosis of ASCUS. 3759 cases were included in study group. The 1200 cases of 3759 were not followed up. Histopathologic diagnosis and cervicovaginal smear results were reviewed and compared according to the qualification of ASCUS. The Chi-square test was used. Results : Histopathologic diagnosis of low-grade squamous intraepithelial lesion (LGSIL) was seen in 46.1%, 47.8%, and 44.3% of the ASCUS FR, ASCUS FD and ASCUS NOS group, respectively. Histopathologic diagnosis of high-grade squamous intraepithelial lesion (HGSIL) was seen in 6.0%, 17.2% and 7.8% of the ASCUS FR, ASCUS FD and ASCUS NOS group, respectively. In ASCUS FR group, 1 invasive carcinoma was detected. In ASCUS FD group, 6 carcinoma in situ (CIS), 2 microinvasive carcinoma, 1 invasive carcinoma and 1 adenosquamous cell carcinoma were detected. In ASCUS NOS group, there were 20 CIS, 5 microinvasive carcinoma, 7 invasive carcinoma and 2 invasive adenocarcinoma. The ASCUS FD group demonstrated significant risk for SIL and more severe lesion but ASCUS FR and ASCUS NOS demonstrated no significant difference. Conclusion : ASCUS FD group has increased risk for detection of SIL or more severe lesion than ASCUS FR or ASCUS NOS group. But there were also significant number of SIL and even invasive cancer in ASCUS FR and ASCUS NOS group, so qualification of ASCUS was not useful for management and colposcopy-directed biopsy is advocated even in ASCUS FR group.
자궁경부 CIS (Carcinoma in Situ)에 있어서 Loop Electrosurgical Excision Procedure (LEEP)의 효용성
유혜리 ( Yu Hye Li ),박영한 ( Park Yeong Han ),김성주 ( Kim Seong Ju ),장봉림 ( Jang Bong Lim ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.10
목적 : 치료와 진단에 유용한 LEEP의 효과를 자궁경부 CIS에서 알아보고자 한다. 연구 방법 : 1999년 1월부터 2002년 4월까지 한림대학교 성심병원 산부인과에 내원하여 질세포진 검사나 조직 생검상 최종적으로 CIS로 진단된 94명의 환자를 대상으로 LEEP 후 질확대경하 조직생검과 LEEP의 조직소견의 비교, 전자궁적출술 후 잔여병변 결과를 비교하였다. 결과 : 1. punch biposy와 LEEP과의 관계로 일치도는 60%, LEEP에서 Objective : The purpose of this retrospective study is to evaluate the efficacy of Loop Electrosurgical Excision Procedure (LEEP) in the diagnosis and in the treatment of CIS (carcinoma in situ). Methods : Between Jan. 1999 and Apr. 2000, 94 patients with
알파 태아단백을 생성하는 난소의 Sertoli-Leydig Cell Tumor
김창모 ( Kim Chang Mo ),박영한 ( Park Yeong Han ),장봉림 ( Jang Bong Lim ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.8
The Sertoil-Leydig cell tumor (SLCT) is gonadal tumor of sex-cord type, similar to that seen in the various phase of testicular development in the male. It is the most common type of all virilizing ovarian tumors and account for less than 0.5% of all ovar