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박수헌,김진일,정인식,김재광,정규원,한준열,선희식,손형선,방춘상,나종순 대한소화기학회 1998 대한소화기학회지 Vol.32 No.1
Background/Airns: Although patients with cirrhosis often complain the gastrointestinal symptoms such as indigestion, little attention has been paid to the possible effects of portal hypertension on gut function. Frequently, endoscopic feature of patients with cirrhosis included congestive gastropathy. However, it has not been shown that whether gastric emptying time is delayed in cirrhotic patients with congestive gastropathy. The aims of this study were to evaluate the gastric emptying in cirrhotic patients with congestive gastropathy and to understand the factors causing the delay of gastric emptying time in patients with cirrhosis. Methods: Between April 1996 and September 1996, 30 cirrhotic patients with congestive gastropathy, 27 cirrhotic patients without congestive gastropathy, and 15 controls were participated in this study at St, Mary Hospital. All patients were subjected to evaluation of gastrointestinal symptom score, endoscopy, Child-Pugh score, and gastric emptying time with solid meal. Results: The gastric emptying time was longer in cirrhotic patients with congestive gastropathy than in controls (105.6±9.58 vs 72.4±6.02 minutes), but there was no significant difference between cirrhotic patierits without congestive gastropathy and controls (93.7±7.93 vs 72.4±6.02 minutes). Among Factors influencing gastric emptying time in cirrhosis such as congestive gastropathy, ascites, gastric varix, AST, ALT, Child-Pugh score, prothrombin time, age, albumin level, esophageal varix, and bilirubin, only the congestive gastropathy was statistically significant (p$lt;0.05). Conclusions: The gastric emptying time was delayed in cirrhotic patients who had congestive gastropathy. Thus, congestive gastropathy may contribute to the pathogenesis of delayed gastric emptying in cirrhosis.
박수헌,정인식,박종원,정규원,김부성,최황,최명규,조세현,선희식,김춘추,한준열,김석은,김동집 대한내과학회 1995 대한내과학회지 Vol.49 No.2
Graft-versus-host disease(GVHD) is a major cause of morbidity and mortality following bone marrow transplantation(BMT). Moderate to severs GVHD occurs in nearly one half of recipients of HLA identical sibling BMT, and 10-30% of these patients die due to acute GVHD or its complications. Target organs injured by GVHD include the skin, liver, and gastrointestinal tract. The clinical staging and grading of acute GVHD are based on the degree of target organ damage. In Korea, the occurrence of GVHD is about 20%. We report four typical eases of histologically con- firmed GUHD after allogeneic BMT, and review the literature to compare the difference$quot; in primary ill-ness, clinical manifestations, and disease progression.
1996년도 제35차 대한소화기학회 추계학술대회 / 일반연제 : 위장관 ; 비궤양성소화불량환자에서 위배출시간지연과 자율신경기능실조의 임상적 의의
박수헌,김진일,나종순,채현석,김재광,한준열,최규용,정인식,정규원,선희식,박두호,손형선 ( Soo Heon Park,Jin Il Kim,Jon Soon Na,Hiun Suk Chae,Jae Kwang Kim,Jun Yul Han,Kyu Yong Choi,In Sik Chung,Kyu Won Chung,Hee Sik Sun,Doo Ho Park,Hyung Su 대한소화기학회 1996 대한소화기학회지 Vol.28 No.1
대장관 내압 상승으로 유발된 허혈성 대장염 15예의 분석
박수헌,김명훈,김기범,조세현,차상복,문성배,배상수,한원희,최규용,조환석 대한소화기내시경학회 1996 Clinical Endoscopy Vol.16 No.6
It was suggested that temporary vascular insufficiency within the wall of the colon causes iachemic colitis. So, motivated by this fact, we studied and analyzed 15 cases of iachemic colitis, which were confirmed by the diagnostic criteria of Nagasako(1982), through 32 months from January, 1993 to August, 1995 at Our Lady of Mercy Hospital, Incheon. The results were as follows: 1) Average age was 51.3 years(17 to 79 years), 10 of 15 cases were above 50 years and the rest were below 50 years. The ratio of men to women was 7:8. 2) The causes were 8 cases of enema, 3 cases' of taking laxative drugs, 3 cases of strain, and 1 case of having colonofiberscopy. 3) The symptoms were 15 cases of abdominal pain(100%), 15 cases of bloody stool (100%), and 7 cases of diarrhea(47%). The signs were 13 cases of abdominal tenderness(87%), 3 cases of fever(20%), and 11 cases of leukocytosis(above 10.0000/㎣)(73 %). 4) The involved sites were 13 cases in the sigpnoid colon(87%), 10 cases in the descending colon(67%), and 9 cases in the rectum(60%). 5) The colonafiberscopc findings were 15 cases of diffuse hyperemia(100%), 13 cases of erosions and hemorrhage(87%), 13 cased of edema(87%). 9 cases of exudate (60%), and 6 cases of ulcer(40%). The longitudinlal hyperemia or shallow ulceration, which are characteristic of colonofiberscopic findings of ischemic colitis, were found in 11 eases(73%). After a week, the follow-up endoscqpy showed that most of lesions were improved. And after another wek, sill cases had recovered. 6) All cases were improved by NPO and fluid therapy; the period of fluid therapy was 5.89 days. 7) The pathological findings were 11 cases of chronic ulceration(79%) and 1 cases each of erosion, superficial hemorrhage, melansis coli(7%). And only a patient was not biopsy.