http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
급성 B 형 간염환자에 있어서 각종 체액내의 HBV Markers 의 발현빈도
조민구(Min Koo Cho),김철우(Cheol Woo Kim),김소연(So Yon Kim),김영중(Young Jung Kim),박병익(Beong Yik Park),강욱(Wook Kang),고창석(Chang Seok Koh),노순태(soon Tae Rho) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.4
N/A HBsAg has been identified in the variable body fluids of HBV-infected persons. In this studv, HBsAg, HBeAg, Anti HBe, & Anti HBc were sought by solidphase RIA in 60 patient with HBsAg-positive acute hepatitis. The results were summarized as follows: 1) In the semen, HBsAg-positive cases were 15 (25%) and HBeAg-positive cases were 6 (10%). 2) In the saliva, HBsAg-positive cases were 28 (46.7%) and HBeAg-positive cases vvere 9 (15%). Some specimens (33.3%) contained occult blood in the saliva, however the incidence of positive HBsAg were not significantly affected by presence of occult hlood. 3) In the urine, 59 cases (98.3%) were negative for HBsAg & HBeAg, but onlv one case (1.67%) with mild microscopic hematuria was positive for urine HBsAg & HBeAg 4)In the sweat, HBsAg & HBeAg were not detected in all the 60 patients.
HbsAg 양성 간질환에 있어서 혈청 IV 형 Collagen - 7S ( 7S domain ) 의 농도
이종봉(Jong Bong Lee),김진석(Jin Seok Kim),문희승(Hee Seung Moon),이석호(Suk Ho Lee),김소연(So Yon Kim),박병익(Beong Yik Park),조민구(Min Koo Cho),김우호(Woo Ho Kim) 대한내과학회 1992 대한내과학회지 Vol.43 No.1
N/A Background: The purpose of this investigation was to determine the usefulness of serum type IV collagen 7S domain in the evaluation of the extent of hepatic fibrosis. We compared the level of serum collagen 7S domain to the degree of collagen type IV staining of hepatic tissue in various liver diseases. Method: We evaluated 70 cases of HBsAg positive patients and 32 cases of normal controls. Serum 7S domains were measured by CGR gammatic 5310 and collagen type IV 7S kit and each hepatic tissue were stained with monoclonal mouse collagen IV (DAKO-COLLAGEN) staining. Result: 1) Compared to 32 normal volunteers (mean±S.D. = 2.8±1.4ng/ml), 7S domain concentrations were moderately elevated in patients with acute viral hepatitis (mean±S.D=5.4±1.8ng/ml; p<0.001) and chronic persistent hepatitis (meankS.D.=5.5±1.4ng/ml; p<0.001), and significantly elevated in chronic active hepatitis (mean+S.D.=8,4±2.3ng/ml; p<0,001) and liver cirrhosis (mean+S.D.=15,1±6.3ng/ml; p<0,001). 2) Compared to patients with acute viral hepatitis, 7S domain concentrations were not elevated in patients with chronic persistent hepatitis but moderately elevated in patients with chronic active hepatitis (p<0.001) and significantly elevated in patients with liver cirrhosis. 3) Compared to patients with chronic active hepatitis, 7S domain contrations were significantly elevated in patients wih liver cirrhosis. 4) The level of serum type IV collagen 75 domains were correlated to the degree of collagen type IV staining in hepatic tissues. Conclusion: These data suggest that 7S domain of collagen type IV serum levels reliably reflect the degree of hepatic fibrosis in patients with chronic liver disease.
간경변증 환자에서 혈청 4형 Collagen-7S의 의의
차경석(Kyoung Seok Cha),한영찬(Young Chan Han),김영태(Young Tae Kim),이숭구(Sung Ku Lee),서대원(Dae Won Seo),김영중(Young Jung Kim),박병익(Beong Yik Park),조민구(Min Koo Cho) 대한소화기학회 1995 대한소화기학회지 Vol.27 No.3
N/A Background/Aims: Cirrhosis is defined anatomically as a diffuse process with fibrosis and nodule formation. Although liver biopsy provides the evaluation of the degree of fibrosis, a simpler diagnostic method would be helpful for its invasive nature. The serum type IV collagen is known recently to indicate the activity of collagen synthesis in the process of fibrosis. This study aims to evaluate the usefulness of serum type IV collagen with the clinical and laboratory findings. Methods: A number of abnormalities were found to be statistically associated with the levels of serum type IV collagen. Included among the clinical abnormalities were pitting edema, ascites, splenomegaly, jaundice, and encephalopathy. The laboratory tests include albumin, tota1 bilirubin, prothrombin time, and alkaline phosphatase. Results: Significant correlations were found between the serum type IV collagen and the grade of the modified Childs classification(p0.05: between class A and B, class B and C, respectively), as well as the CCLI(comhined clinical and laboratory index, r=0.74, Y=6.78 +0.71X, p0.001). Conclusions: These results suggest that the serum type IV collagen may be a sensitive marker of fibrotic process and may reflect the present state and prognosis in cirrhosis. (Korean J Gastroenterol 1995;27:331 337)
조민구(Min Koo Cho),강남영(Nam Yeong Kang),신화식(Hwa Sig Shin),김철우(Cheol Woo Kim),정순영(Sun Young chung),김소연(So Yon Kim),김영중(Young Jung Kim),박병익(Beong Yik Park),강진국(Jin Kook Kang) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.2
A case of carcinoma associated with choledochal cyst in a 25 year-old male is presented. The choledochal cyst is relatively rare lesion in the biliary system, moreover the carcinoma developed in the choledochal cyst has been reported rarely. The patient has complained of epigastric pain, fever and chill. Abdominal CT scan and ultrasonography showed markedly dilated left intrahepatic duct and common bile duct. At operation, grossly there was a true cystic dilatation from left intrahepatic duct to common bile duct and a hard nodular mass at the posterior wall of the dilated common bile duct. Microscopically this was moderately well differentiated adenocarcinorna surrounded by desmoplastic reaction at the infiltrated wall of the extrahepatic duct.
김학수,김영중,오영하,노영호,안민,박병익,차영학,김윤권,전종구,안현석 대한신장학회 1999 Kidney Research and Clinical Practice Vol.18 No.2
Alport's syndrome is a hereditary disorder whose incidence is 1 in 10,000 in general population, and, majority are developed in childhood, so it is rare to develop in adults. This syndrome consists of hematuria, sensorineural hearing loss, and lenticonus, in classic form. However, there are many atypical forms which have not all clinical manifestations. Although most asymptomatic hematuria in adults results from IgA nephropathy(Berger's disease) or thin basement disease(benign hematuria), Alport's syndrome should be considered as a cause of hematuria. The authors experienced a case of Alport's syndrome in a 21-year-old man who showed only hematuria and proteinuria, and who was diagnosed by history, family history, audiogram, and kidney needle biopsy. So, we report this case with a review of literature.
김홍남,류광현,김소연,시석,김진욱,최동섭,황인섭,박병익,최병진,김학수,김윤권 대한감염학회 1997 감염 Vol.29 No.3
저자들은 안면부 등의 경화를 주소로 내원한 28세 남자환자에서 당뇨병 등의 동반 질환이 없이 급성 상기도 감염에 속발하여 발생한 경화부종 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Scleredema is a rare connective tissue disease of unknown etiology and characterized by nonpitting thickening of subcutaneous tissue of the neck, face, head, upper trunk and arms. We present a 28 year-oldman with extensive skin changes following upper respiratory infection, who have not any concurrent disorders such as diabetes mellitus. Histopathological findings of skin showed normal epidermis with a widening of spaces between collagen bundles by infiltration of acid mucopolysaccharide in the dermis.