C57BL/6 마우스에서 천연 식물성추출물(아벨모)의 발모효능 및 작용 메카니즘

박상오Sang-Oh Park,박병성Byung-Sung Park,노가영Ga-Yeong Noh 한국유화학회 2014 한국응용과학기술학회지 Vol.31 No.4

This study was determined the hair growth effect and mode of action of a complex extract (abelmo), extracted from various natural plants including Acorus calamus var. angustatus. 30 six-week old C57BL/6 mice were randomly assigned into three treatment groups with ten mice per treatment group repeatedly. The treatment group is a control group, and was classified into saline-applied, minoxidil 5%-applied, and abelmo-applied groups. Hair growth started from the abelmo-applied and minoxidil 5% -applied groups on the 9th day, compared to the saline-applied group. Hair growth rate was 17.06% and 19.15% in those two groups, respectively, and the abelmo-applied group s hair growth rate was higher. The density, length and thickness of hair were significantly higher in the order of abelmo-applied group, minoxidil 5%-applied group and saline-applied group on the 9th day, and hair root was strongly maintained in the abelmo-applied group. The density, length and thickness of hair in the abelmo-applied group were significantly higher by 599.8, 122.2 and 181.8% on the 9th day compared to the saline-applied group, and 166.7, 171.4 and 200.2% on the 12th day, and 136.6, 216.9 and 180.7%, respectively on the 15th day. As for hair follicle and the length of hair shaft from the dosal skin histopathology manifestation, the abelmo-applied group was more excellent than the saline-applied group and minoxidil 5%-applied group. This result actually confirmed the fact that abelmo promotes hair growth and strongly maintains hair root simultaneously.

소나무껍질 추출물(피타민)을 섭취한 닭고기의 품질 및 저장성

박병성,Park, Byung-Sung 한국축산식품학회 2009 한국축산식품학회지 Vol.29 No.4

A component of pine bark extract, pitamin, is known as an antioxidant and antimicrobial agent that exerts a variety of physiological effects; this compound has also been used widely in human beings. A 35-day trial was conducted to determine the influence of dietary pitamin premix via a sensory evaluation and evaluations of the TBARS, and meat quality in broiler chicken. We used 4 treatments groups: Control, Antibiotics, Pitamin premix 0.1%, and Pitamin premix 0.2%. The amino acid and protein contents in chicken breast muscle did not differ among the treatment groups. The pH of broilers fed on diets containing pitamin premix was lower (p<0.05) than broilers fed on the control and antibiotics diets, whereas the WHC was significantly higher in chicken breast muscles fed on the diet containing pitamin premix compared to the control and antibiotics groups (p<0.05). The TBARS is intended to be increased during the storage period (in days), and was significantly lower (p<0.05) in the chicken thigh muscles with skin from broilers fed on the diet containing the pitamin premix as compared to the control and antibiotics group (p<0.05). The sensory evaluation of boiled chicken, with the exception of the antibiotics group, revealed significantly better results from chickens fed on diets containing pitamin premix than the control group (p<0.05). These results suggest that dietary pitamin premix may improve the shelf life, flavor, taste, and meat quality in broiler chicken.

돼지고기의 콜레스테롤 함량 감소에 관한 β-Cyclodextrin의 급여효과

박병성,Park, Byung-Sung 한국식품영양과학회 2006 한국식품영양과학회지 Vol.35 No.3

The main objective of the present study was to determine the effect of dietary ${\beta}-cyclodextrin\;({\beta}CD)$ on reducing the cholesterol content of pork. Twelve swine of 50 kg body weight were randomly distributed into four groups of three heads each and fed experimental diets for 9 weeks until they reached a market weight of 110 kg. They were assigned to the four experimental diets containing 0% (control), 1.5%, 3.0% or 5.0% pure ${\beta}CD$. Daily feed intake, body weight gain and feed efficiency were not significantly different between any of the four group. The plasma total lipid, triacylglycerol and total cholesterol content of the swine in the three ${\beta}CD$-fed groups were significantly (p<0.05) decreased when compared to those in the control group, and were significantly (p<0.05) reduced by 21.80%,55.58% and 27.69%, respectively, in the swine fed on 5% ${\beta}CD$. The cholesterol content of pork belly (mg/100g) was significantly (p<0.05) decreased by 5.33 mg, 12.70 mg and 15.23 mg in the swine maintained on 1.5%, 3.0% and 5.0% ${\beta}CD$, respectively. The cholesterol content of pork belly, when expressed as the rate of reduced cholesterol, was significantly (p<0.05) decreased by 6.44%, 15.36% and 18.42% in groups of 1.5%, 3.0% and 5.0% ${\beta}CD$, respectively, when compared to that of the control group. These results suggest that dietary ${\beta}CD$ may be classified as dietary fiber which can modulate cholesterol metabolism in swine. 본 연구의 주목적은 돼지고기의 콜레스테롤 함량 감소에 관한 사료 내 ${\beta}CD$의 급여 효과를 조사하는 것이었다. 생체중 50 kg의 3원교잡종 거세 수퇘지 12마리를 이용하여서 4처리구 3반복으로 완전임의배치한 후, 시판체중인 110 kg 도달시까지 약 9주 동안 실험사료를 급여하였다. 일일 사료섭취량, 일일 증체량 및 사료효율은 ${\beta}CD$를 첨가하지 않은 대조구와 비교할 때, ${\beta}CD$ 1.5%, 3.0% 및 5.0% 첨가구의 각 처리구간 통계적인 유의차가 나타나지 않았다. 혈액 총지질, 중성지방 및 총콜레스테롤 함량은 대조구와 비교할 때 ${\beta}CD$ 첨가구가 유의적으로 낮아졌으며, 특히 ${\beta}CD$ 5.0% 첨가구에서 각각의 감소율은 21.80%, 55.58% 및 27.69%로서 가장 높게 나타났다(p<0.05). 돼지고기 삼겹살의 콜레스테롤 함량은 대조구와 비교할 때 ${\beta}CD$ 1.5%, 3.0% 및 5.0% 첨가구에서 각각 5.33mg, 12.70mg및 15.23 mg의 유의적인 감소를 나타났으며, 특히 이 값을 콜레스테롤의 감소율로서 나타냈을 때 각각 6.44%, 15.36%, 18.42%로서 유의적인 차이를 나타냈다(p<0.05). 이 결과는 돼지에서 ${\beta}CD$첨가급여가 콜레스테롤 대사를 조절할 수 있는 식이섬유로서 사용될 수 있음을 시사해준다.

고지방식이 유도된 흰쥐의 혈액지질 및 간에 관한 파리유충 추출물의 효과

박병성(Park Byung Sung) 한국유화학회 2009 한국응용과학기술학회지 Vol.27 No.3

The bioactive effects of ethanol extracts from fly maggot (ME) on reduction of plasma lipids levels in rats fed high-fat diets (Expt. Ⅰ), and on liver function recovery of hepatotoxicity rats by intraperitoneal injection of carbon tetrachloride (CCl4) or by orally administration of alcohol (Expt. Ⅱ) were investigated. In expt. Ⅰ, twenty seven, male rat SDS(sprague dawley strain) were randomly assigned to three treated groups, including normal control group, HF (group with high fat diets which have no extracts) and HFE (HF plus orally administered doses of ME extract at 5.0 mg/100g of body weight). In expt. Ⅱ, forty five, male rats (SDS) were randomly assigned to each of the five groups: T1 (control), T2 (intraperitoneal injection of CCl4), T3 (intraperitoneal injection of CCl4 after orally administered with ME), T4 (orally administered with combination of ME and alcohol), T5 (orally administration of ME after orally administered with alcohol). There were significant decreases in plasma (TAG), (TC), (LDL-C) in the HFE group with orally administered doses of ME at 5.0 mg/100g of body weight, respectively, however, the (HDL-C) were significantly increased in HFE group as compared to HF group with high fat diets which have no extracts (p<0.05). The levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), γ-glutamyl transferse(γ-GTP) and bilirubin were highest in T2 or T3, and high in order T4 or T5, and lowest in T1 except for bilirubin which has same with T4, T5 (p<0.05). The high recovery of liver damage by CCl4 from the light microscopic appearance was observed in rats (T3) with extracts, and also high in T4 than T5 by orally administrated with alcohol. In conclusion, the ethanol extracts from fly maggot may have a bioactive effects to prevent for human lipids disorder and alcoholic disease.

삼씨유와 달맞이유의 급여가 계란 내 감마지방산 축적에 미치는 영향

박병성 ( Byung Sung Park ) 한국유화학회 2008 한국응용과학기술학회지 Vol.25 No.2

Effects of Dietary Inuloprebiotics on Egg Production and on the Microbial Ecology and Blood Lipid Profile of Laying Hens

Sang-Oh Park(박상오),Byung-Sung Park(박병성) 한국생명과학회 2012 생명과학회지 Vol.22 No.7

본 연구는 산란계 사료 내 항균성장촉진제로써 돼지감자(Helianthus tuberosus L.)로부터 추출, 제조한 이눌로프리바이오틱스(Inuloprebiotics, INP)의 고수준 첨가가 산란능력 및 계란품질에 미치는 영향을 조사하기 위해 실시 하였다. 29주령의 갈색산란계(Hyline brown) 320마리를 이용하여 처리구당 80마리씩 개체별, 반복구로 나누어서 완전임의 배치한 후 10주 동안 실험사료를 급여하였다. 실험처리구는 T1 (무첨가 대조군), T2 (INP 450 ppm 첨가군), T3 (INP 600 ppm 첨가군) 및 T4 (INP 750 ppm 첨가군)로 구분하였다. 산란율, 난중, 사료섭취량 및 계란의 호우유니트, 난각두께, 파란강도는 T1과 비교할 때 T2, T3, T4가 유의하게 높았으나(p<0.05) T2, T3, T4 사이의 통계적인 유의차는 인정되지 않았다. 계란의 콜레스테롤은 T1이 가장 높았고 T4, T3, T2 순서로 이눌로프리바이오틱스 첨가구에서 15.04-17.98%까지 유의하게 감소하였다(p<0.05). 계란 포화지방산 조성은 T2, T3, T4가 T1에 비해서 낮았으나 불포화지방산은 그 반대로 유의하게 높았다(p<0.05). 혈액 중성지방 및 총콜레스테롤은 T1과 비교할 때 T2, T3, T4에서 21.71-24.07% 및 27.17-30.36%로 유의하게 감소하였다(p<0.05). 맹장의 유익한 미생물, Bifidobacterium, Lactobacillus의 성장은 T2, T3, T4가 T1과 비교할 때 자극되었으나 유해한 Escherichia, Salmonella의 성장은 뚜렷하게 억제되었다(p<0.05). 본 연구결과는 이눌로프리바이오틱스 450 ppm을 산란계 사료 내 첨가해주면 산란성적 및 계란품질을 향상시킬 수 있음을 시사해준다. This study was carried out to investigate the effects of inuloprebiotics (INPs), an alternative antibacterial growth promotor, from Jerusalem artichoke extract (Helianthus tuberosus L.) on egg production and quality in Hyline brown laying hens. The hens were divided randomly into four treatment groups and housed in individual cages for 10 weeks: a control group (0 ppm INP) (T1), 450 ppm (T2), 600 ppm (T3), and 750 ppm (T4). Egg production, egg weight, Haugh unit, eggshell thickness, and breaking strength were significantly higher in all of the INP-treated groups compared with the control (p<0.05). Egg cholesterol was highest in the T1 group and decreased with INP addition from 15.04 to 17.98% (p<0.05). Compared with the T1 group, triglycerides in the blood and in total cholesterol decreased significantly in groups T2, T3, and T4 by 21.71-24.07% and 27.17-30.36%, respectively (p<0.05). The growth of cecum Bifidobacterium and Lactobacillus was stimulated in groups T2, T3, and T4 compared with T1, whereas the growth of Escherichia and Salmonella was clearly inhibited (p<0.05). The results suggest that the addition of 450 ppm INP to the diet of laying hens can improve egg production and egg quality.

안드로이드 기반 UI 장치 플러그인 기술 설계

박병성(Park Byung Sung),박경민(Park Kyung Min),최훈(Choi Hoon) 한국통신학회 2009 한국통신학회 학술대회논문집 Vol.2009 No.11

육계의 성장능력 향상을 위한 이눌로프리바이오틱스의 적정 첨가수준 결정

Byung-Sung Park(박병성) 한국생명과학회 2011 생명과학회지 Vol.21 No.5

본 연구는 브로일러의 성장능력을 촉진하기 위한 사료 내 이눌로프리바이오틱스의 적정 첨가수준을 결정하기 위하여 수행하였다. 부화 당일 로스계통(Ross 308)의 브로일러 수컷 320수를 4개의 처리구로 완전임의배치하여 35일 동안 사육하였다. 실험처리구는 대조구(무첨가구), 항생제 첨가구(avilamycin 8 ppm), 이눌로프리바이오틱스 200 ppm 첨가구 및 이눌로프리바이오틱스 250 ppm 첨가구로 구분하였다. 브로일러의 체중과 사료섭취량은 두개의 이눌로프리바이오틱스 첨가구가 대조구, 항생제 첨가구 보다도 높았고, 항생제 첨가구는 대조구에 비해서 높았으며 통계적인 유의차가 인정되었다. 전체 실험기간 동안 사료요구율은 대조구가 이눌로프리바이오틱스 첨가구와 비교할 때 유의하게 높았으나 항생제 첨가구와 이눌로프리바이오틱스 첨가구 사이의 통계적인 유의차는 없었다. 도체중, 도체율, 가슴살, 다리살의 무게는 이눌로프리바이오틱스 첨가구가 대조구, 항생제 첨가구에 비해서 유의하게 높았고, 이눌로프리바이오틱스 200 ppm, 250 ppm 첨가구 사이의 차이는 없었으나 항생제 첨가구는 대조구에 비해서 유의하게 높았다. 복강지방은 이눌로프리바이오틱스 첨가구가 유의하게 감소(19.08~23.30%)하였으며 혈액 면역물질과 흉선, F낭의 무게는 이눌로프리바이오틱스 첨가구가 대조구와 항생제 첨가구에 비해서 유의하게 증가하였다. 장내 유익한 Bifidobacteria와 Lactobacillu는 이눌로프리바이오틱스 첨가구가 대조구와 항생제 첨가구에 비해서 유의하게 증가하였으나 유해한 E. coli와 Salmonella는 그 반대로 나타났으며 통계적인 유의차가 인정되었다. 본 연구는 브로일러의 성장능력 향상을 위한 사료 내 이눌로프리바이오틱스의 적정 첨가수준은 200 ppm에서 결정될 수 있음을 보여준다. The present study furthered this research by determining the optimal level of inuloprebiotics derived from Korean Jerusalem artichoke to promote growth in broiler chickens. On hatch day, 320 male Ross 308 broilers were randomly allotted to four groups for a 35-day feeding regimen. The groups were a control (no supplementation), diet supplementation with antibiotics (8 ppm avilamycin), supplementation with 200 ppm inuloprebiotics, and supplementation with 250 ppm inuloprebiotics. Body weight and feed intake were comparably high in the two inuloprebiotics groups, and exceeded the values for the control and antibiotics groups. Body weight and feed intake was higher in chickens fed the antibiotics supplemented diet, compared to controls. There were significant differences among treatment groups. Feed conversion ratio during total experimental periods was significantly high in the control group compared to the inuloprebiotics-fed groups, but no significant difference was evident using antibiotics or inuloprebiotics dietary supplementation. Carcass weight, dressing percentage, and weight of breast and thigh muscle were significantly higher for inuloprebiotics-fed chickens, compared with control and antibiotic-fed chickens. Inuloprebiotics concentration was not significant, while antibiotics-fed chickens displayed significantly higher values than control chickens. Abdominal fat was significantly reduced (19.08%?23.30%) and blood immunoglobulin and the weight of the thymus and Bursa of Fabricius were significantly increased in chickens receiving inuloprebiotics-supplemented feed, compared to control and antibiotics fed groups. In the lower intestine, the viable counts of beneficial bacteria (Bifidobacteria and Lactobacillus) were significantly increased and counts of harmful bacteria (Escherichia coli and Salmonella sp.) were significantly decreased in the presence of the inuloprebiotics, compared to control and antibiotic. The present results support 200 ppm as an optimal level of Korean Jerusalem artichoke-derived inuloprebiotics as a dietary supplement to improve growth in broiler chickens.

감마 리놀렌산의 혈액 지질 대사

박병성(Byung Sung Park) 한국유화학회 2002 한국응용과학기술학회지 Vol.19 No.3

N/A The purpose of this study was to determine the effect of dietary γ-linolenic acid on plasma lipid metabolism and antithrombotic activity in male Sprague Dwaley Strain rats. Rats weighing an average of 100∼120g were fed a experimental diets containing 5% lard (saturated fatty acids), corn oil(linoleic acid), evening promise oil(EPO, 9% γ-linolenic acid) or borage oil(BO, 24% γ-linolenic acid) for 30days, respectively. Though there were no significant difference in the food intake among the groups, the body weight gain of the BO group was significantly lower than that of other group. The spleen weight of the lard group was significantly lower than that of other group. The bleeding time of the BO group was significantly longer than that of other group. The blood clotting time was significantly tended to long in EPO and BO groups compared with lard group. The plasma triacylglyceride and total cholesterol concentration were high in order of lard, corn oil, EPO and BO, groups and there were significant differences among the groups. The plasma HDL-C concentrations were high in order of BO, EPO, corn oil and lard groups and there were significant differences among the groups. The plasma LDL-C concentrations were significantly the highest in lard group, but the lowest in BO group. These data indicate that γ-linolenic acid has a antithrombotic activity, and decrease the plasma triacylglyceride, total cholesterol and LDL-C concentrations in rats.

닭고기의 품질 및 맛에 관한 계피 급여효과

박병성(Byung-Sung Park) 한국식품영양과학회 2008 한국식품영양과학회지 Vol.37 No.5

브로일러에서 계피의 첨가급여가 브로일러의 성장능력, 혈액지질, 도체특성, 닭고기의 품질특성 및 계피맛, 향과 관련한 닭고기의 맛에 미치는 영향을 연구하였다. 병아리는 CNP를 함유하지 않은 대조구, CNP 2.0%, CNP 3.0%, CNP 4.0% 및 CNP 5.0% 첨가구로 구분하였다. 브로일러의 사료 섭취량, 사료효율은 대조구와 비교할 때 처리구간 차이가 없었으나 체중은 CNP 3% 이상으로 첨가수준이 증가함에 따라서 유의적인 개선을 나타냈다(p<0.05). 혈액의 중성지방, HDL-C는 대조구에 비해서 CNP 첨가수준이 높아질수록 증가하는 경향을 나타냈으나, 총 콜레스테롤, LDL-C는 뚜렷하게 감소하였으며 각 처리구간 통계적 유의차가 있었다(p<0.05). 도체율은 CNP 첨가구가 대조구에 비해서 높았고, 닭 다리살은 CNP 3.0% 이상에서 증가하였으며, 닭 가슴살은 CNP 2.0%와 4.0% 첨가구가 높은 경향이었다(p<0.05). 닭 가슴살의 pH는 대조구와 비교하여 유의차가 없었으나, 보수력은 CNP 4% 이상 첨가수준이 높아질수록 증가하였고, TBARS는 CNP 3% 이상 첨가수준이 높아질수록 유의적으로 낮아졌다(p<0.05). 닭 가슴살의 육색은 CNP 첨가수준이 3% 이상 증가할수록 대조구에 비해서 더욱 밝은 색을 나타냈다(p<0.05). 닭 다리살 튀김과 삶은 닭 가슴살에서 계피와 관련한 맛, 향에 대한 관능평가 성적은 대조구와 비교할 때 CNP 첨가수준이 높아질수록 유의적으로 높게 나타났다(p<0.05). 본 실험에서 나타난 중요한 점은 브로일러 사료에 계피를 첨가 급여해줌으로써 닭고기의 도체특성과 맛을 개선할 수 있다는 사실이었다. A 35-day trial was carried out to determine the influence of dietary cinnamon powder (CNP) on the sensory evaluation and quality of chicken meat, carcass characteristics, plasma lipid level and growth performance of broiler chickens. There were 5 treatment groups: control; CNP 2.0%; CNP 3.0%; CNP 4.0%; and CNP 5.0%. The body weight of the broilers fed the diets containing 3.0% CNP was higher than the broilers fed the control feeds (p<0.05). The concentration of triacylglyceride, HDL-C was higher in the plasma from broiler chickens fed diets with CNP (p<0.05) but the concentrations of total cholesterol and LDL-C were significantly lower (p<0.05) compared to the control group. The carcass percentage, chicken breast and thigh weight were not different between the CNP and control groups. The WHC was significantly higher in the chickens fed 4% CNP diet, while the TBARS was significantly lower (p<0.05) in the chickens fed 3% CNP diet compared to the control group. The color of the breast muscle from the chickens fed 3% CNP diet was lighter than those from the control groups (p<0.05). The sensory evaluation of the taste and savor related to CNP in fried or boiled chicken meat were significantly better from the broiler chicken fed diets containing CNP than the control group (p<0.05). These results suggest that dietary cinnamon powder may improve savor and quality of chicken meat in broiler chickens.