방사선조사가 하악과두에 미치는 영향에 관한 전자현미경적 연구

박명선,박태원,Park Myoung Seon,Park Tae Won 대한영상치의학회 1996 Imaging Science in Dentistry Vol.26 No.2

In attempt to determine radiation effect on the mandibular condyle of the growing rat, 27 white female rats (Sprague-Dawley) were divided into 3 groups and irradiated respectively 5Gy, 10Gy, 20Gy using MK Cell Irradiator. Mandibular condyles from rats on the day of 1, 7, 14 after the irradiation day were obtained, sectioned sagittally and examined by light microscopy, and thereafter middle portion through anteroposterior direction on the sagittal plane was selected to examine the ultrastructural change by transmission electron microscopy. The obtained results are followings. 1. In the proliferative zone some cells showed little organelles in case of 5Gy irradiation, in addition the number of degenerative cells increased and in case of 10Gy irradiation, and in case of 20 Gy irradiation total number of cells decreased. 2. In the hypertrophic zone, narrowing of width and partial disorder in hypertrophic process were noted in case of 5 Gy irradiation, and more prominent narrowing of width and more irregular disorder in hypertrophic process in case of both 10Gy and 20Gy irradiation. 3. In the upper hypertrophic zone some chondrocytes seemed to be dying and the polarity of nuclei could not be seen, if any. 4. The periodic observation showed the severest change at day 7 and the signs of recovery at day 14 after irradiation.

이면성 심초음파도에 의한 관상동맥 우회로술후 좌심실 국소 벽운동의 변화

원수연(Soo Yeon Won),전일문(Il Mun Jeon),박명선(Myoung Seon Park),장명규(Myoung Kyu Jang),유재규(Jae Kyu Ryu),정진원(Jin Won Jeong),박양규(Yang Kyu Park),박옥규(Ock Kyu Park),최종범(Jong Bum Choi) 대한내과학회 1993 대한내과학회지 Vol.45 No.6

N/A Objectives: Studies on the effect of Coronary Artery bypass Graft Surgery (CABG) on segmental left ventricular wall motion have yield conflicting results. So we assessed changes of segmental left ventricular wall motion in patients with coronary artery disease after CABG and advantage of 2dimensional echocardiography on evaluating its effectiveness. Methods: 20patients with coronary artery disease (12unstable angina pectoris, 8 acute myocardial infarction) were studied with 2-dimensional echocardiography before and early 8.3±3.3 (mean±SD) and late 204.5±105.9 days after CABG. The changes in segmental wall motion were assessed quantitatively by assigning a segmental wall motion score recommended by ASE (1: normal, 2: hypokinesia 3: akinesia, 4: dyskinesia, 5: aneurysm) to each of 16echocardiographically defined segments by 45-degree rotating apical 4-plane views (8 in basal, 8 in apical). Results: 1) The mean left ventricular segmental wall motion score did not change significantly (1, 10±0.37, l.25±0.47, 1.12±0.40; befror, early and late after CABG respectively). 2) There was a significant change in septal wall motion at early postoperative study [37 (46%) of the 80septal segments; 1.14±0.41, 1.59±0.59(p<0.001): before and early after CABG respectively], and the worsening segments were nearly normalized at late postoperative study [24(92%) of 26segments]. 3) The segments with normal motion preoperatively remained normal late postoperatively [169(99%) of 171normal segments preoperatively]. 4) Most of the preoperative abnormal segments [23(96%) of 24segments] were in patients with acute MI and a half of them (11segments) were normalized at late postoperative study. 5) While the anterior or anteroseptal preoperative abnormal segments were usually improved postoperatively, the posterior or inferior abnormal segments were not changed significantly. Conclusion: A part of the abnormal segmental left ventricular wall motion in coronary artery disease can be improved after CABG and 2-dimensional echocardiography may be beneficial to assessing not only the changes of segmental left ventricular wall motion motion quantitatively but also the effectiveness of CABG.

현상처리된 치과용 방사선필름의 크롬 증강효과에 대하여

박명선,박태원 大韓口腔顎顔面 放射線學會 1990 Imaging Science in Dentistry Vol.20 No.2

This study was undertaken to determine (1) the usefulness of chromium intensifier to improve the dignostic quality of light radiograph; (2) the effect of chromium intensifier on density, contrast;and (3) the effect of various chemical concentrations on density. the following results obtained : 1. CHROMIUM INTENSIFIER is useful for intensifying and improving the diagnostic quality of a light dental radiograph. 2. The degree of intensification can be controlled by varying bleaching time, repeating the processing, varying the proportions of the potassium bicarbonate and hydrochloric acid solutions. 3. The image produced is black and permanent. 4. The intensifier increases density and contrast.

3대에 걸쳐 발생한 유전성 구상 적혈구증

장명규,유재규,박명선,이용구,윤귀현,조지현,문영회 大韓血液學會 1994 大韓血液學會誌 Vol.29 No.1

영양실조성 당뇨병 2 예

조정구,박명선,유광현,장명규,손성식,송승렬 대한내과학회 1994 대한내과학회지 Vol.46 No.2

Malnutrition-related diabetes mellitus is a form of diabetes peculiar to developing countries within the tropical belt, which comprises two subgroups, fibrocalculous pancreatic diabetes (FCPD) and protein-deficient pancreatic diabetes (PDPD). FCPD is a form of diabetes secondary to chronic calcific pancreatitis, which is not due to alcohol consumption and tend to affect younger people and characterized by insulin-requiring but ketosis-resistant and coexisting malnutrition or pancreatic duct stone. FCPD is diagnosed by demonstrating calculi and signs of chronic pancreatitis by radiographic or ultra-sound imaging, together with evidence of pancreatic exocrine insufficiency. We recently experienced the two cases of fibrocalculous pancreatic diabetes. MRDM deserves further study not only because it is now recognized as a major form of the disease but also because it may improve our understanding of other forms of diabetes.

피부 병변 및 전신임파선증을 동반한 급성 골수성 백혈병 환자 1 예

이용구,송승렬,박명선,유재규,강정성,원수연,전일문,장명규 대한내과학회 1993 대한내과학회지 Vol.45 No.6

We describe a patient with acute myelogenous leukemia who demonstrated striking leukemia infiltration in back and large cervical, axillary and inguinal 1ymphadenopathy, A 62-year-old man had visited to our hospital with complaints of sore throat, cervical lymphadenopathy and multiple nodules on the skin. Skin biopsy specimen showed diffuse dermal, subcutaneous and fat infiltration of abnormal cells that appeared to be leukemic cell in nature. Bone marrow biopsy and aspiration specimen showed findings of acute monocytic leukemia. Treatment was initiated with combination chemotherapy (Thioguanine, Daunorubicin and Cytarabine) and radiation therapy. We report one case of acute monocytic leukemia patient who had multiple leukemia infiltration on the skin and generalzed lymphadenopathy.

단일 관상동맥 1예

전일문,원수연,박명선,정진원,박양규,박옥규 圓光大學校 醫科學硏究所 1993 圓光醫科學 Vol.9 No.1-2

Single coronary artery is rare and occur in 0.03% to 0.4% of the population. In about 40% of the reported cases it is associated with other congenital anomalies. The prognosis for patients with a single coronary' artery varies from excellent with no decrease in life expectancy to sudden death. Single coronary artery may contribute to angina because a relatively small proximal vessel may either become diseased or make distal coronary arterial lesions more hemodynamically significant by reducing coronary blood flow. We report a case of single coronary artery originated from left single coronary ostium in a 37-year-old male with atypical chest pain.

과립구 집락촉진인자 ( G - CSF )에 의한 항갑상선제 유도 무과립세포증 치험 1 예

이용구,조정구,유광현,손성식,송승렬,박명선 대한내분비학회 1993 Endocrinology and metabolism Vol.8 No.3

Agranulocytosis represents a life-threatening complication of antithyroid therapy, occurring in 0. 1% to 1% of patients. Course and duration of agranulocytosis may be highly variable. Recently, recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF) and granulocyte colony stimulating factor (fhG-CSF) have proved useful in the treatment of idiopathic aplastic anemia, idiopathic neuropenia, and chemotherapy-associated agranulocytosis. That G-CSR might also be useful in drug-induced allergic-toxic agranulocytosis. We experienced successful rhG-CSF treatment of a 25-year-old woman who had propylthiouracil induced agrnulocytosis. The availability of G-CSF may help to shorten the course of agranulocytosis and to reduce its fatality rate (J Kor Soc Endocrinol 8:347~350, 1993).