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      • KCI등재후보

        간흡충 감염가토의 간내 담관에 대한 병리조직학적 및 조직화학적 연구

        송근암(Geun Am Song),김진도(Jin Do Kim),이동완(Dong Wan Lee),손춘희(Choon Hee Son),양웅석(Ung Suk Yang),허윤(Yoon Hue),문한규(Han Gue Moon),유방현(Bang Hyun Liu),이선경(Sun Kyung Lee) 대한내과학회 1989 대한내과학회지 Vol.37 No.3

        N/A This study was undertaken to examine the histopathological changes of the bile duct in rabbits heavily infested with Clonorchis sinensis for 6-18 months, and then to investigate the histochemical properties and compositions of epithelial mucosubstances. In 9 rabbits, each rabbit was orally infested with about 500 metacercariae and was sacrificed when general conditions were poor. The specimens were stained with H-E, PAS, alcian blue (pH 2.5), alcian blue (pH 1.0), alcian blue (pH 2.5) -PAS, and FITC- conjugated lectins. The results obtained were as follow 1) The pathological changes in the infested rabbits were papillary and adenomatous hyperplasia, goblet cell and mucus-cell metaplasia, ductal wall fibrosis, and infiltration of eosinophils in the ductal wall, and then the metaplasia of ductal epithelium was more marked in the deep gland than in the surface. 2) The epithelial mucosubstances in the normal intrahepatic bile duct were produced in the border and supranuclear portion of the epithelium. The histochemical composition of these was a mixture of neutral and acid mucosubstances with a predominant acid group. 3) In infested rabbits, the epithelial mucosubstances were produced in the border and supranuclear portion of the covering epithelium, goblet cell, and hyperplasia and metaplasia cells of the deep gland. The mucosubstances were much more produced in the goblet cell, hyperplasia and metaplasia cell of deep gland, and the composition was mixture of neutral and acid substances with a predominance of the neutral group in goblet cell and adenomatous hyperplasia, and a predominance of the acid group in mucus-cell metaplasia of the deep gland. 4) In the normal intrahepatic bile duct, labeling of FITC-conjugated lectins of WGA and Con-A was weakly localized in the border of the epithelium and its grade was trace. 5) In infested rabbits, F1TC-WGA and FITC-Con-A labeling was seen in the border and supranuclear portion of the covering epithelium, goblet cell, and hyperplasia and metaplasia cells of the deep gland, but FITC-PNA and FITC-SBA labeling was graded from zero to trace. 6) Mucin secreting cell metaplasia stained by PAS and AB showed very significant labeling of E1TC-WGA and FITC-Con-A, which are lectins that are highly specific in their recognition of glycosylated residues.

      • SCOPUSKCI등재

        내시경적 담석 제거술의 임상적 고찰

        문한규,양웅석,유방현,송근암,이동완,허윤 대한소화기내시경학회 1988 Clinical Endoscopy Vol.8 No.2

        Endoscopic sphincterotomy (E.S.T.) has relatively low complications and is the theraphy of choice in patients with common bile duct stones. It is also an useful technique for decompression of biliary tract obstruction. Thirty two cases of patients were selected according to opedrative risks: old age, severe jaundice and recurrent or retained bile duct stones after cholecystecomy from 1986 to 1988. The results were as follows, 1) In thirty two cases nf E.S.T., male to female ratio was 1:1.46. Most frequent age was older than 40 years. (male, 84.6%, female, 84.2%). 2) Out of thirty two cases, 20 cases (62.5% were under post clholecystectomy state, 12 eases (37.5%) were obstructive jaundice. 3) Spontaneous stone passage after E.S.T. was 81.3% (26 cases), and total stone remoral rate was 87.5% (28 cases), 4) Complications of E.S.T. were noted in three cases. In the two cases of bleeding, it was spontaneously improved and a case of acute pancreatitis was treated by medical care.

      • KCI등재후보

        구조물의 변형률 측정을 위한 광섬유 TR-EFPI 센서의 개발

        최만용,문한규,권일범,김민수 한국센서학회 2000 센서학회지 Vol.9 No.2

        Fiber optic TR-EFPI(total reflected extrtinsic Fabry-Perot interferometric) sensor was developed to measure the strain of structures, such as building, bridge, aircraft, etc. It has been difficult to distinguish the increase and decrease of the strain from the conventional fiber optic EFPI sensor because their signals only have a sinusoidal wave pattern related to the change of strain. Also, the absolute strain could not be measured by the simple fiber optic EFPI sensor. In this study, in order to measure the magnitude of strain with the direction of strain, the fiber optic sensor was simply constructed with the total reflected EFPI sensor probe. This probe was manufactured with a single mode fiber and a mirror coated fiber in a silica glass capillary tube. The output signal of this fiber optic TR-EFPI sensor can give the information about the magnitude and the direction of strain. The loading-unloading test was performed by the universal testing machine with alluminum beam specimen to compare the strain from fiber optic TR-EFPI sensor with the value from electrical strain gauge. In the result of this experiment, the strain from fiber optic TR-EFPI sensor had a good agreement with the values from the electrical strain gauge.

      • KCI등재

        Fe-13Cr-5Ni-12Mn 합금의 탄성과 자성에 관한 연구

        이재옥,안병덕,문한규,송기영 대한금속재료학회(대한금속학회) 1991 대한금속·재료학회지 Vol.29 No.1

        Variation of elastic constants and magnetic susceptibility with temperature variation of austenitic Fe-_(13)C_r-_5N₁-_(12)M_6 stainless steel alloy were measured in the temperature range between 77K and 295K. The alloy showed the elastic costant anomalies at the same temperature as that for magnetic transition. Through the analysis of the sharp cusp on the susceptibility curve, the magnetic thermohysteresis, the spin order parameter, etc., it was confirmed that the magnetic transition occured in this alloy is the Ising mean field paramagnetic-spin glass transition of de Alemeida-Thouless type.

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